Validity of digital assessments in screening for HIV-related cognitive impairment: a review
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Purpose of review While traditional neuropsychological tests are the gold standard in screening for HIV-related cognitive impairment, computerized neuropsychological assessment devices (CNADs) offer an alternative to these time- and resource-intensive batteries and may prove to be particularly useful for remote assessments or longitudinal monitoring. This review seeks to describe the benefits, limitations, and validity of CNADs in the evaluation of HIV-associated neurocognitive disorder (HAND).Recent findings We identified eight CNADs that have undergone validity testing for cognitive impairment in the setting of HIV. Included among these are batteries that have been modeled after the traditional neuropsychological exam, as well as others that implement new technologies, such as simulated reality and daily ecological assessments in their testing. Currently, these digital batteries do not yet have the ability to supplant gold standard neuropsychological tests in screening for HAND. However, many have the potential to become effective clinical screening tools.
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Digital cognitive assessment tools have been developed to replace and improve upon traditional cognitive measures, but their development remains in the early stages.
“Digital cognitive assessment tools have been developed to replace and improve upon traditional cognitive measures, but their development remains in the early stages (30).”
From Research on digital tool in cognitive assessment: a bibliometric analysis (2023) · cites this paper as [30]
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Robbins, R. N., Nanteza, A., Gumikiriza‐Onoria, J. L., Santoro, A. F., Ferraris, C. M., Karungi, C., Tsapalas, D., Asiedu, N., Kirsch, C., Tan, M., et al. (2026) · JMIR mhealth and uhealth · doi:10.2196/103288
- Authors
- Wilson, S., Milanini, B., Javandel, S., Nyamayaro, P., & Valcour, V.
- Affiliations
- University of California, San Francisco (US)
- University of Zimbabwe (ZW)
- Corresponding author
- Valcour, Victor
- Venue
- Current HIV/AIDS Reports
- Published
- 2021-11-25
- Volume
- 18
- Issue
- 6
- Pages
- 581-592
- ISSN
- 1548-3568 (ISSN-L)
- 1548-3576
- PMC
- PMC8612826
- OpenAlex
- W3216760998
- Cited by
- 10
- References
- 84
- Citations by year
- 2026: 2 · 2024: 3 · 2023: 2 · 2022: 3
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Current HIV/AIDS Reports (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH113406)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- HIV-associated neurocognitive disorders, computerized neuropsychological assessment, cognitive screening, remote assessment, long-term monitoring, simulated reality, ecological assessment, neuropsychological assessment
- MeSH terms
- Humans, Mass Screening, Neuropsychological Tests, HIV Infections, Neurocognitive Disorders, Cognitive Dysfunction
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