Are sleep-related breathing disorders important contributing factors to the production of essential hypertension?
Abstract
About 50% of all patients with essential hypertension have obstructive sleep apnea (OSA), and another 40% of essential hypertension patients are habitual snorers, but without OSA. There is now convincing evidence that both OSA and habitual snoring are independent risk factors for essential hypertension, and that treatment of OSA will reduce the blood pressure. There is also some evidence that treatment of habitual snoring will also reduce the blood pressure. If this is the case, then we postulate a unifying hypothesis: that these two sleep-related breathing disorders (SRBD) (OSA and habitual snoring) are very common contributing factors to what is called "essential hypertension." The many epidemiologic, clinical, hematologic, biochemical, and physiologic findings seen in essential hypertension could also be due to the associated SRBD. A routine search for SRBD by asking a few simple questions of all patients (especially those with hypertension) and their bed partners could increase the number of patients detected and treated significantly. Successful treatment of SRBD would improve sleep quality and the associated excessive daytime sleepiness, and thus improve the quality of life. In addition, there is a good chance that the hypertension will improve as well.
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Epidemiologic studies support a strong relationship between OSA and hypertension.
“Epidemiologic studies support the strong relationship between OSA and hypertension.(112)”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [112]
The prevalence of OSA in individuals with hypertension is estimated to be about 40-50% and approaches 83% in patients with resistant hypertension.
“The prevalence of OSA in individuals with hypertension is estimated to be about 40-50%(112) and approaches 83% in patients with resistant hypertension(86).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [112]
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- Authors
- Silverberg, D. S., & Oksenberg, A.
- Affiliations
- Tel Aviv Sourasky Medical Center (IL)
- Venue
- Current Hypertension Reports
- Published
- 2001-06
- Volume
- 3
- Issue
- 3
- Pages
- 209-215
- ISSN
- 1522-6417 (ISSN-L)
- 1534-3111
- OpenAlex
- W2055930891
- Cited by
- 97
- References
- 61
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 10 · 2022: 6 · 2021: 6 · 2020: 4 · 2019: 7 · 2018: 6 · 2017: 4 · 2016: 2 · 2015: 8 · 2014: 2 · 2013: 2 · 2012: 2
- FWCI
- 0.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Hypertension Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- essential hypertension, obstructive sleep apnea, habitual snoring, sleep-disordered breathing, hypertension risk factors, blood pressure reduction, OSA treatment, excessive daytime sleepiness, sleep quality
- MeSH terms
- Blood Pressure, Circadian Rhythm, Humans, Hypertension, Risk Factors, Sleep Apnea Syndromes, Snoring, Sleep Apnea, Obstructive
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