Cited by 162Nutrition and Health in AgingBody Composition Measurement TechniquesFrailty in Older Adults

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Clinical Implications of Sarcopenic Obesity in Cancer

Carneiro, Isabella P., Mazurak, Vera C., Prado, Carla M.·2016·Current Oncology Reports

DOI 10.1007/s11912-016-0546-5

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Abstract

Sarcopenia has been associated with several negative clinical outcomes in cancer. However, the consequences of sarcopenic obesity, a condition of combined sarcopenia and obesity burden, have been less extensively investigated. The aim of this paper was to review the current evidence on the prevalence and clinical implications of sarcopenic obesity in cancer. A total of 14 studies linking sarcopenic obesity to a clinical outcome in cancer were included. There is considerable inconsistency in methods used to evaluate body composition as well as in the criteria used to define sarcopenic obesity, which limits comparison among studies. Therefore, the prevalence of sarcopenic obesity varied substantially: between 1 and 29 % in studies including individuals from all body mass index categories and between 15 and 36 % for those including obese individuals only. Negative clinical outcomes reported to be associated with sarcopenic obesity included higher risk of dose-limiting toxicity, surgical complications, physical disability, and shorter survival.

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“[33] reviewed the clinical implications of SO in cancer reporting negative clinical outcomes associated with SO.”
Background
Diabetes and Sarcopenic Obesity: Pathogenesis, Diagnosis, and Treatments
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“Other complications associated with sarcopenic obesity include poor functional status, worse postoperative outcomes, prolonged hospitalization, and shorter survival.(47) Among patients with cancer, prevalence of sarcopenia ranges from 12%–51% when diagnosed with both body composition and functional assessment tools an…”
Background

See all 162

Authors: Carneiro, I. P., Mazurak, V. C., & Prado, C. M.
Affiliations: University of Alberta (CA)
Corresponding author: Prado, Carla M.
ORCID: Mazurak, Vera C.
Prado, Carla M.
Venue: Current Oncology Reports
Publisher: Springer Science and Business Media LLC
Published: 2016-08-19
Volume: 18
Issue: 10
Pages: 62-62
ISSN: 1523-3790 (ISSN-L)
1534-6269
DOI: 10.1007/s11912-016-0546-5
OpenAlex: W2518082324
Cited by: 162
References: 77
Citations by year: 2026: 9 · 2025: 13 · 2024: 15 · 2023: 19 · 2022: 15 · 2021: 23 · 2020: 22 · 2019: 19 · 2018: 17 · 2017: 9 · 2016: 1
FWCI: 1.80
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (unspecified)
Locations: Current Oncology Reports (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Keywords: sarcopenic obesity, sarcopenia, obesity, cancer, body composition, prevalence, dose-limiting toxicity, surgical complications, physical disability, survival, clinical outcomes
MeSH terms: Antineoplastic Combined Chemotherapy Protocols, Body Composition, Dose-Response Relationship, Drug, Humans, Neoplasms, Obesity, Prevalence, Survival Analysis, Treatment Outcome, Sarcopenia

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Clinical Implications of Sarcopenic Obesity in Cancer

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