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Cited by 538

The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.

Treatment of Tendinopathy: What Works, What Does Not, and What is on the Horizon

Open access
Andres, Brett M., Murrell, George A. C.·2008·Clinical Orthopaedics & Related Research
DOI 10.1007/s11999-008-0260-1
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Abstract

UNLABELLED: Tendinopathy is a broad term encompassing painful conditions occurring in and around tendons in response to overuse. Recent basic science research suggests little or no inflammation is present in these conditions. Thus, traditional treatment modalities aimed at controlling inflammation such as corticosteroid injections and nonsteroidal antiinflammatory medications (NSAIDS) may not be the most effective options. We performed a systematic review of the literature to determine the best treatment options for tendinopathy. We evaluated the effectiveness of NSAIDS, corticosteroid injections, exercise-based physical therapy, physical therapy modalities, shock wave therapy, sclerotherapy, nitric oxide patches, surgery, growth factors, and stem cell treatment. NSAIDS and corticosteroids appear to provide pain relief in the short term, but their effectiveness in the long term has not been demonstrated. We identified inconsistent results with shock wave therapy and physical therapy modalities such as ultrasound, iontophoresis and low-level laser therapy. Current data support the use of eccentric strengthening protocols, sclerotherapy, and nitric oxide patches, but larger, multicenter trials are needed to confirm the early results with these treatments. Preliminary work with growth factors and stem cells is promising, but further study is required in these fields. Surgery remains the last option due to the morbidity and inconsistent outcomes. The ideal treatment for tendinopathy remains unclear. LEVEL OF EVIDENCE: Level II, systematic review.

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Crossref · 10.1007/s11999-008-0260-1

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Metadata

Authors
Andres, B. M., & Murrell, G. A. C.
Venue
Clinical Orthopaedics & Related Research
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2008-07
Volume
466
Issue
7
Pages
1539-1554
ISSN
0009-921X (ISSN-L)
DOI
10.1007/s11999-008-0260-1
OpenAlex
W2021499515
Cited by
538
References
126
FWCI
16.61
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Treatment of Tendinopathy: What Works, What Does Not, and What is on the Horizon. https://app.cochat.ai/papers/10.1007/s11999-008-0260-1
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Andres, B. M., & Murrell, G. A. C. (2008). Treatment of Tendinopathy: What Works, What Does Not, and What is on the Horizon. Clinical Orthopaedics & Related Research. https://doi.org/10.1007/s11999-008-0260-1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.