The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
SegAN: Adversarial Network with Multi-scale L1 Loss for Medical Image Segmentation
Open accessAbstract
Inspired by classic Generative Adversarial Networks (GANs), we propose a novel end-to-end adversarial neural network, called SegAN, for the task of medical image segmentation. Since image segmentation requires dense, pixel-level labeling, the single scalar real/fake output of a classic GAN’s discriminator may be ineffective in producing stable and sufficient gradient feedback to the networks. Instead, we use a fully convolutional neural network as the segmentor to generate segmentation label maps, and propose a novel adversarial critic network with a multi-scale L1 loss function to force the critic and segmentor to learn both global and local features that capture long- and short-range spatial relationships between pixels. In our SegAN framework, the segmentor and critic networks are trained in an alternating fashion in a min-max game: The critic is trained by maximizing a multi-scale loss function, while the segmentor is trained with only gradients passed along by the critic, with the aim to minimize the multi-scale loss function. We show that such a SegAN framework is more effective and stable for the segmentation task, and it leads to better performance than the state-of-the-art U-net segmentation method. We tested our SegAN method using datasets from the MICCAI BRATS brain tumor segmentation challenge. Extensive experimental results demonstrate the effectiveness of the proposed SegAN with multi-scale loss: on BRATS 2013 SegAN gives performance comparable to the state-of-the-art for whole tumor and tumor core segmentation while achieves better precision and sensitivity for Gd-enhance tumor core segmentation; on BRATS 2015 SegAN achieves better performance than the state-of-the-art in both dice score and precision.
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Cites
U-Net: Convolutional Networks for Biomedical Image Segmentation
Ronneberger, O., Fischer, P., & Brox, T. (2015) · Lecture notes in computer science · doi:10.1007/978-3-319-24574-4_28 · Cited by 99,404
A Computational Approach to Edge Detection
Canny, J. (1986) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.1986.4767851 · Cited by 30,004
Image-to-Image Translation with Conditional Adversarial Networks
Isola, P., Zhu, J.-Y., Zhou, T., & Efros, A. A. (2017) · 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2017.632 · Cited by 22,930
Unsupervised representation learning with deep convolutional generative adversarial networks
Radford, A., Metz, L., & Chintala, S. (2015) · arXiv · doi:10.48550/arxiv.1511.06434 · Cited by 12,235
Improved Techniques for Training GANs
Salimans, T., Goodfellow, I., Zaremba, W., Cheung, V., Radford, A., & Chen, X. (2016) · arXiv · doi:10.48550/arxiv.1606.03498 · Cited by 6,965
Semantic Image Segmentation with Deep Convolutional Nets and Fully Connected CRFs
Chen, L.-C., Papandreou, G., Kokkinos, I., Murphy, K., & Yuille, A. L. (2014) · arXiv · doi:10.48550/arxiv.1412.7062 · Cited by 4,213
Efficient multi-scale 3D CNN with fully connected CRF for accurate brain lesion segmentation
Kamnitsas, K., Ledig, C., Newcombe, V. F. J., Simpson, J. P., Kane, A. D., Menon, D. K., Rueckert, D., & Glocker, B. (2017) · Medical Image Analysis · doi:10.1016/j.media.2016.10.004 · Cited by 3,498 · cited 3×
“In this subsection, we compare the proposed method, our S3-3C SegAN model, with other state-of-the-art methods on the BRATS 2013 Leaderboard [11, 26] Test and the BRATS 2015 Test [13].”
MethodBrain tumor segmentation with Deep Neural Networks
Havaei, M., Davy, A., Warde-Farley, D., Biard, A., Courville, A., Bengio, Y., Pal, C., Jodoin, P.-M., & Larochelle, H. (2017) · Medical Image Analysis · doi:10.1016/j.media.2016.05.004 · Cited by 3,278
Brain Tumor Segmentation Using Convolutional Neural Networks in MRI Images
Pereira, S., Pinto, A., Alves, V., & Silva, C. A. (2016) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2016.2538465 · Cited by 2,735
Efficient Piecewise Training of Deep Structured Models for Semantic Segmentation
Lin, G., Shen, C., van den Hengel, A., & Reid, I. (2016) · 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr.2016.348 · Cited by 862
Cited by
Image segmentation using deep learning: A survey
Minaee, S., Boykov, Y. Y., Porikli, F., Plaza, A. J., Kehtarnavaz, N., & Terzopoulos, D. (2021) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.2021.3059968 · Cited by 3,796
A Review on Generative Adversarial Networks: Algorithms, Theory, and Applications
Gui, J., Sun, Z., Wen, Y., Tao, D., & Ye, J. (2023) · IEEE Transactions on Knowledge and Data Engineering · doi:10.1109/tkde.2021.3130191 · Cited by 1,231
Bandi, A., Adapa, P. V. S. R., & Kuchi, Y. E. V. P. K. (2023) · Future Internet · doi:10.3390/fi15080260 · Cited by 638
Durall, R., Keuper, M., & Keuper, J. (2020) · 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr42600.2020.00791 · Cited by 26
Shifting machine learning for healthcare from development to deployment and from models to data
Zhang, A., Xing, L., Zou, J., & Wu, J. C. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-022-00898-y · Cited by 420
Metadata
- Authors
- Xue, Y., Xu, T., Zhang, H., Long, L. R., & Huang, X.
- Venue
- Neuroinformatics
- Published
- 2018-05-03
- Volume
- 16
- Issue
- 3-4
- Pages
- 383-392
- ISSN
- 1539-2791 (ISSN-L)
- 1559-0089
- OpenAlex
- W2622064152
- Cited by
- 605
- References
- 10
- FWCI
- 36.64
- Type
- journal article
- Language
- en
- Open access
- green
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