The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics
Open accessAbstract
Exosomes have emerged as prominent mediators of neurodegenerative diseases where they have been shown to carry disease particles such as beta amyloid and prions from their cells of origin to other cells. Their simple structure and ability to cross the blood–brain barrier allow great opportunity to design a “makeup” with drugs and genetic elements, such as siRNA or miRNA, and use them as delivery vehicles for neurotherapeutics. Their role in neuroprotection is evident by the fact that they are involved in the regeneration of peripheral nerves and repair of neuronal injuries. This review is focused on the role of exosomes in mediating neurodegeneration and neuroprotection.
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1 retracted
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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
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Role for a bidentate ribonuclease in the initiation step of RNA interference
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Membrane vesicles as conveyors of immune responses
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Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
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Cited by
Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
Kim, M. S., Haney, M. J., Zhao, Y., Mahajan, V., Deygen, I., Klyachko, N. L., Inskoe, E., Piroyan, A., Sokolsky, M., Okolie, O., et al. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.10.012 · Cited by 1,410
Ha, D., Yang, N., & Nadithe, V. (2016) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2016.02.001 · Cited by 1,346
Using exosomes, naturally-equipped nanocarriers, for drug delivery
Batrakova, E. V., & Kim, M. S. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.07.030 · Cited by 1,041
Elucidation of Exosome Migration Across the Blood–Brain Barrier Model In Vitro
Chen, C. C., Liu, L., Ma, F., Wong, C. W., Guo, X. E., Chacko, J. V., Farhoodi, H. P., Zhang, S. X., Zimak, J., Ségaliny, A., et al. (2016) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-016-0458-3 · Cited by 537
The potential of endurance exercise-derived exosomes to treat metabolic diseases
Safdar, A., Saleem, A., & Tarnopolsky, M. A. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.76 · Cited by 463
Metadata
- Authors
- Kalani, A., Tyagi, A., & Tyagi, N.
- Venue
- Molecular Neurobiology
- Published
- 2013-09-03
- Volume
- 49
- Issue
- 1
- Pages
- 590-600
- ISSN
- 0893-7648 (ISSN-L)
- 1559-1182
- OpenAlex
- W2006645013
- Cited by
- 332
- References
- 112
- Type
- book review
- Language
- en
- Open access
- green
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- Kalani, A., Tyagi, A., & Tyagi, N. (2014). Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics. Molecular Neurobiology. https://doi.org/10.1007/s12035-013-8544-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
