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Nuclear reprogramming and epigenetic rejuvenation
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The idea of inducing epigenetic transition to a 'youthful' state without the loss of cell identity, defined as 'epigenetic rejuvenation', was proposed for the first time in 2010.
“The idea of inducing epigenetic transition to a 'youthful' state without the loss of cell identity, defined as 'epigenetic rejuvenation', was proposed for the first time in 2010 (refs.99-101).”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [101]
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Cites
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“Currently, these are lacking although the presence of partially reprogrammed or ‘metastable’ pluripotent states found in iPS cell studies (Hanna et al. 2009a, b; Chan et al. 2009) may provide a rich source of material for the study of factors that reprogramme characteristic features of aged cells such as SAHF.”
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Research works printed but not linked: 25
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Sorted by citations
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming
Cipriano, A., Moqri, M., Maybury-Lewis, S. Y., Rogers-Hammond, R., de Jong, T. A., Parker, A., Rasouli, S., Schöler, H. R., Sinclair, D. A., & Sebastiano, V. (2023) · Nature Aging · doi:10.1038/s43587-023-00539-2 · Cited by 66
Promises of reprogramming-induced rejuvenation
Simpson, D. J., Arif, N., Suwanlikit, Y., Kirschner, K., & Chandra, T. (2026) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2026.102484 · Cited by 2
Metadata
- Authors
- Singh, P. B., & Zacouto, F.
- Venue
- Journal of Biosciences
- Published
- 2010-04-19
- Volume
- 35
- Issue
- 2
- Pages
- 315-319
- ISSN
- 0250-5991
- 0973-7138
- Cited by
- 23
- References
- 1
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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