The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Two-photon-excited near-infrared emissive carbon dots as multifunctional agents for fluorescence imaging and photothermal therapy
Abstract
C dots (CDs) have shown great potential in bioimaging and phototherapy. However, it is challenging to manipulate their fluorescent properties and therapeutic efficacy to satisfy the requirements for clinic applications. In this study, we prepared S, Se-codoped CDs via a hydrothermal method and demonstrated that the doping resulted in excitation wavelength-independent near-infrared (NIR) emissions of the CDs, with peaks at 731 and 820 nm. Significantly, the CDs exhibited a photothermal conversion efficiency of ~58.2%, which is the highest reported value for C nanostructures and is comparable to that of Au nanostructures. Moreover, the CDs had a large two-photon absorption cross section (~30,045 GM), which allowed NIR emissions and the photothermal conversion of the CDs through the two-photon excitation (TPE) mechanism. In vitro and in vivo tests suggested that CDs can function as new multifunctional phototheranostic agents for the TPE fluorescence imaging and photothermal therapy of cancer cells.
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Cites
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Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications
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Self-citationA multifunctional chemical toolbox to engineer carbon dots for biomedical and energy applications
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Metadata
- Authors
- Lan, M., Zhao, S., Zhang, Z., Yan, L., Guo, L., Niu, G., Zhang, J., Zhao, J., Zhang, H., Wang, P., Zhu, G., Lee, C.-S., & Zhang, W.
- Venue
- Nano Research
- Publisher
- Tsinghua University Press
- Published
- 2017-05-11
- Volume
- 10
- Issue
- 9
- Pages
- 3113-3123
- ISSN
- 1998-0000 (ISSN-L)
- 1998-0124
- OpenAlex
- W2612674108
- Cited by
- 305
- References
- 49
- FWCI
- 11.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lan, M., Zhao, S., Zhang, Z., Yan, L., Guo, L., Niu, G., Zhang, J., Zhao, J., Zhang, H., Wang, P., Zhu, G., Lee, C.-S., & Zhang, W. (2017). Two-photon-excited near-infrared emissive carbon dots as multifunctional agents for fluorescence imaging and photothermal therapy. Nano Research. https://doi.org/10.1007/s12274-017-1528-0
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