Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts
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Fluorescent light-excited zinc meta N-methylpyridylporphyrin induces oxidative DNA damage in human colon carcinoma LS174T cells, tentatively assigned as 8-oxoGua.
“Fluorescent light-excited zinc meta N-methylpyridylporphyrin has been shown to induce oxidatively generated damage to DNA of human colon carcinoma LS174T cells, tentatively assigned as 8-oxoGua (184) on the basis of somewhat questionable immunodetection (185).”
From Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions<sup>†</sup> (2012) · cites this paper as [185]
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References 269 · Cited by 38
- Authors
- Cadet, J., Douki, T., Ravanat, J.-L., & Wagner, J. R.
- Affiliations
- Université de Sherbrooke (CA)
- Université Joseph Fourier (FR)
- Corresponding author
- Cadet, Jean
- Venue
- Bioanalytical Reviews
- Published
- 2012-03-27
- Volume
- 4
- Issue
- 2-4
- Pages
- 55-74
- ISSN
- 1867-2086 (ISSN-L)
- 1867-2094
- OpenAlex
- W1994712179
- Cited by
- 38
- References
- 269
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 7 · 2016: 3 · 2014: 6 · 2013: 4 · 2012: 1
- FWCI
- 1.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Bioanalytical reviews (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Keywords
- DNA oxidation, HPLC-MS/MS, HPLC-electrochemical detection, interstrand cross-links, DNA repair enzymes, alkaline comet assay, alkaline elution, immunoassay cross-reactivity, 5-hydroxymethylcytosine, mitochondrial DNA, nuclear DNA
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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