Using qualitative comparative analysis to understand and quantify translation and implementation
Open accessAbstract
Understanding the factors that facilitate implementation of behavioral medicine programs into practice can advance translational science. Often, translation or implementation studies use case study methods with small sample sizes. Methodological approaches that systematize findings from these types of studies are needed to improve rigor and advance the field. Qualitative comparative analysis (QCA) is a method and analytical approach that can advance implementation science. QCA offers an approach for rigorously conducting translational and implementation research limited by a small number of cases. We describe the methodological and analytic approach for using QCA and provide examples of its use in the health and health services literature. QCA brings together qualitative or quantitative data derived from cases to identify necessary and sufficient conditions for an outcome. QCA offers advantages for researchers interested in analyzing complex programs and for practitioners interested in developing programs that achieve successful health outcomes.
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QCA can examine complex combinations of explanatory factors across differing contexts and produce externally valid results even among a smaller sample.
“QCA can examine complex combinations of explanatory factors (or pathways) across differing contexts and produce externally valid results even among a smaller sample [39–41].”
From Using qualitative comparative analysis to uncover multiple pathways to program sustainment: implications for community-based youth substance misuse prevention (2022) · cites this paper as [40]
The Advantages and Limitations of QCA section says QCA examines combinations of conditions while retaining each case’s context, and can support small-N studies. It does not say that results from small samples are externally valid; it also cautions that too few cases can leave possible configurations unrepresented. No page number is available in our copy. (LLM, conf=0.88)
Experimental — accuracy not yet measuredCrisp-set QCA can improve interpretation and provide clearer practice implications.
“as noted by several implementation researchers, crisp-set QCA can improve interpretation and provide clearer practice implications [33, 40].”
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Percentages, sums and reported differences re-computed from the paper’s own numbers.
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Masters, C., Carandang, R. R., Lewis, J. B., Hagaman, A. K., Metrick, R., Ickovics, J. R., & Cunningham, S. D. (2024) · Implementation Science Communications · doi:10.1186/s43058-024-00556-1 · Cited by 3 · see citing works
Advancing Implementation: Toward an Inclusive View of Research in Behavioral Medicine
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Competencies of Bridge Managers for Facilitating Global R&D Projects
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Applying qualitative comparative analysis in a systematic review: Lessons learned
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Abduction in the Assessment of Special Educational Needs - Learning Disability
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- Authors
- Kane, H., Lewis, M. A., Williams, P. A., & Kahwati, L. C.
- Affiliations
- RTI International (US)
- Corresponding author
- Kane, Heather
- Venue
- Translational Behavioral Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-01-22
- Volume
- 4
- Issue
- 2
- Pages
- 201-208
- ISSN
- 1613-9860 (ISSN-L)
- 1869-6716
- PMC
- PMC4041929
- OpenAlex
- W2065088369
- Cited by
- 124
- References
- 27
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 15 · 2023: 21 · 2022: 14 · 2021: 13 · 2020: 9 · 2019: 14 · 2018: 12 · 2017: 10 · 2016: 5 · 2015: 1
- FWCI
- 17.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Translational Behavioral Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Sociology and Political Science › Qualitative Comparative Analysis Research
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Education › Qualitative Research Methods and Applications
- Keywords
- qualitative comparative analysis, implementation science, translational research, program implementation, necessary and sufficient conditions, health services research
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