The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Clinical trials-related knowledge, attitudes, and behaviors among Black and Latina women: A randomized controlled trial of the Women United: Clinical Trials and the Fight Against Breast Cancer Program
Abstract
Black and Latino adult cancer patients are underrepresented in cancer clinical trials, which limits generalizability of findings and amplifies disparities in healthcare access and outcomes. Community-level education programs designed to address barriers to participation could improve representation in cancer clinical trials. Through a community-campus partner framework, this study evaluated the Women United: Clinical Trials and the Fight Against Breast Cancer Program in Spanish and English. Participants were 422 women (141 Black, 140 Latina Spanish preference, 141 Latina English preference) who were randomized to view either the intervention (n = 215) or a control (n = 207) program. Assessments of clinical trials knowledge and barriers to clinical trials participation were taken before and after viewing. Results suggested that clinical trials knowledge increased and perceived barriers to participation decreased for those who viewed the educational program. More specifically, those in the intervention condition perceived fewer barriers related to personal benefits, mistrust, and familiarity of clinical trials. As expected, there were no differences in perceived barriers related to community support for either condition. Participants in both conditions were equally likely to join a subsequent study or a clinical trials community ambassador program. There were no differences in any of the outcomes across ethnicity or language, suggesting the program works equivalently across groups. This program is easy to administer and can be recommended for use among Black and Latina women to address factors related to clinical trials participation.
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Seven included studies centred on the recruitment of Hispanic or Latin American individuals.
“Although 7 studies centred on the recruitment of Hispanic or Latin American individuals [12, 15, 36, 50, 51, 57, 66], most of them did not differentiate between the terms Hispanic”
From Enablers and barriers of clinical trial participation in adult patients from minority ethnic groups: a systematic review (2025) · cites this paper as [51]
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Metadata
- Authors
- Merz, E. L., Riley, N. E., Malcarne, V. L., & Sadler, G. R.
- Affiliations
- California State University, Dominguez Hills (US)
- Vista Community Clinic (US)
- San Diego State University (US)
- Corresponding author
- Merz, Erin L.
- Venue
- Journal of Cancer Education
- Published
- 2022-04-07
- Volume
- 37
- Issue
- 3
- Pages
- 874-881
- ISSN
- 0885-8195 (ISSN-L)
- 1543-0154
- OpenAlex
- W4224295158
- Cited by
- 6
- References
- 18
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Update notices
- correction (2022-04-25)
- Open access
- closed
- Locations
- Journal of Cancer Education (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- california breast cancer research program (13AB-3500, 14BB-2601)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Keywords
- clinical trial participation, breast cancer, Black women, Hispanic women, underrepresentation in clinical trials, community education programs, barriers to clinical trial participation, community support, language differences, university-community collaboration
- MeSH terms
- Black or African American, Breast Neoplasms, Clinical Trials as Topic, Female, Health Education, Hispanic or Latino, Humans, Health Knowledge, Attitudes, Practice
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