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Extraction of bioactive compounds from mango (Mangifera indica L. var. Carabao) seed kernel with ethanol–water binary solvent systems
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Mango seed kernel, a by-product of the processing industry, can be valorized as a potential source of bioactive compounds. Binary mixtures of ethanol and water, used in solid-liquid extraction (SLE), have drawn interest as an effective means of recovering phytochemicals from plant materials because these solvents can be used in food applications and their synergistic effect makes them a superior solvent over their pure counterparts. Total phenolic content (TPC) and HPLC chromatograms of each ethanolic extract revealed that ethanol concentration had a significant effect on phenolic compound recovery, wherein, TPC of mango kernel varied from 18.19 to 101.68 mg gallic acid equivalence (GAE) per gram of sample. Subsequently, the antioxidant activities (AOAc) of the extracts, measured by scavenging activities with the DPPH+ (1,1-diphenyl-2-picrylhydrazyl) radical and ferric reducing antioxidant power (FRAP) assay, ranged from 8.19 to 85.45 mmol/L and 3.82-55.61 mmol/L Trolox equivalence, respectively. The solvent containing 50% (w/w) ethanol-water had the highest TPC and exhibited the most potent reducing and radical scavenging activities. With the use of an HPLC-UV/Vis, gallic acid, caffeic acid, rutin and penta-O-galloyl-β-d-glucose were identified to be present in the mango seed kernel. Results show that the mango seed kernel is a viable source of bioactive compounds which can be recovered with water-ethanol binary solvent systems.
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“One study evaluated the effect of ethanol concentration on the extraction of phenolic compounds from mango seed kernel and concluded that increasing the ethanol content from 75% to 100% resulted in a decrease in the recovery of gallic acid [40].”
From On the Path to Sustainable Cosmetics: Development of a Value-Added Formulation of Solid Shampoo Incorporating Mango Peel Extract (2023) · cites this paper as [40]
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Acceptability of Mango Seed Kernel (Mangifera Indica) as Potential Tea Source
Alican, R. P. (2024) · Journal of Healthcare and Biomedical Science · doi:10.31098/jhbs.v3i1.2706 · Cited by 1
Evaluation of the phytochemical constituents and proximate analysis of stem bark of Mangifera indica
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(2021) · International journal of research studies in biosciences · doi:10.20431/2349-0365.0902003 · Cited by 1
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Fatores socioeconômicos e saúde de crianças em contexto de violência - DOI 10.29327/226091.54.1-10
Aquino, E. V. D. O., de Ataíde, B. D. G., Oliveira, I. A., Lima, B. M. Y., Machado, H. C. P., & de Faria, M. R. G. V. (2021) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
A Novel Mango (Mangifera indica L.) Seed Waste-Based Biorefinery Scheme
Bello, F., & Chimphango, A. F. A. (2023) · Springer eBooks · doi:10.1007/978-981-19-7481-6_12
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Subprodutos industriais de tomate ("Solanum lycopersicum" L.)
da Silva, L. C. (2023) · doi:10.47749/t/unicamp.2023.1378220
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Valorization of Subtropical Fruit Wastes as Sources of Bioactive Compounds
Chamorro, F., Álvarez, J. E., Pereira, A. G., Silva, A., Seyyedi-Mansour, S., Donn, P., Perez-Vazquez, A., Barciela, P., Carpena, M., & Prieto, M. A. (2026) · Springer eBooks · doi:10.1007/978-3-642-36202-6_286-1
Radical Scavenging and Anticancer Activities of Lebanese Sarcopoterium spinosum Fruit Extracts
Ghsein, A., Fatfat, Z., Fatfat, M., Khalife, H. K., & Gali‐Muhtasib, H. U. (2026) · Natural Product Communications · doi:10.1177/1934578x261451347
Metadata
- Authors
- Lim, K. J. A., Cabajar, A. A., Lobarbio, C. F. Y., Taboada, E. B., & Lacks, D. J.
- Affiliations
- Case Western Reserve University (US)
- University of San Carlos (PH)
- ORCID
- Lacks, Daniel J.
- Venue
- Journal of Food Science and Technology
- Published
- 2019-04-01
- Volume
- 56
- Issue
- 5
- Pages
- 2536-2544
- ISSN
- 0022-1155 (ISSN-L)
- 0975-8402
- PMC
- PMC6525705
- OpenAlex
- W2928536096
- Cited by
- 114
- References
- 36
- Citations by year
- 2026: 25 · 2025: 17 · 2024: 18 · 2023: 23 · 2022: 11 · 2021: 14 · 2020: 6
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Food Science and Technology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- USAID-STRIDE
- DOST-ERDT
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Keywords
- mango seed kernel, mango, Carabao mango, solid-liquid extraction, phenolic compounds, antioxidant activity, gallic acid, caffeic acid, rutin, penta-O-galloyl-β-D-glucose, bioactive compounds, fruit waste valorization
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