The selective androgen receptor modulator GTx‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double‐blind, placebo‐controlled phase II trial

Dalton, James T.; Barnette, Kester G.; Bohl, Casey E.; Hancock, Michael L.; Rodriguez, Domingo; Dodson, Shontelle T.; Morton, Ronald A.; Steiner, Mitchell S.

doi:10.1007/s13539-011-0034-6

The selective androgen receptor modulator GTx‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double‐blind, placebo‐controlled phase II trial

BackgroundCachexia, also known as muscle wasting, is a complex metabolic condition characterized by loss of skeletal muscle and a decline in physical function. Muscle wasting is associated with cancer, sarcopenia, chronic obstructive pulmonary disease, end-stage renal disease, and other chronic c…