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Designing a drug delivery system for improved tumor treatment and targeting by functionalization of a cell-penetrating peptide

Al-azzawi, Shafq, Masheta, Dhafir·2019·Journal of Pharmaceutical Investigation
DOI 10.1007/s40005-018-00424-w
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  1. Al-Azzawi S, Masheta D, Guildford AL, Phillips G, Santin M (2018) Dendrimeric poly(epsilon-lysine) delivery systems for the enhanced permeability of flurbiprofen across the blood-brain barrier in Alzheimer’s disease. Int J Mol Sci. https://doi.org/10.3390/ijms19103224 · DOI · Paper page
  2. Bechara C, Sagan S (2013) Cell-penetrating peptides: 20 years later, where do we stand? FEBS Lett 587(12):1693–1702. https://doi.org/10.1016/j.febslet.2013.04.031 · DOI
  3. Bolhassani A, Jafarzade B, Mardani G (2017) In vitro and in vivo delivery of therapeutic proteins using cell penetrating peptides. Peptides 87:50–63. https://doi.org/10.1016/j.peptides.2016.11.011 · DOI
  4. Chung EJ, Cheng Y, Morshed R, Nord K, Han Y et al (2014) Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma. Biomaterials 35(4):1249–1256. https://doi.org/10.1016/j.biomaterials.2013.10.064 · DOI
  5. Cooley C, Wender P, Geihe E (2012) Beyond cell penetrating peptides: designed molecular transporters. Dr Discov Today Technol 9(1):e49–e55. https://doi.org/10.1016/j.ddtec.2011.07.004 · DOI
  6. D’souza AJ, Topp EM (2004) Release from polymeric prodrugs: linkages and their degradation. J Pharm Sci 93(8):1962–1979. https://doi.org/10.1002/jps.20096 · DOI
  7. Diop N, Zhao R, Visentin M, Goldman ID (2011) Mechanisms of membrane transport of folates into cells and across epithelia. Ann Rev Nutr. https://doi.org/10.1146/annurev-nutr-072610-145133 · DOI
  8. Dissanayake S, Denny WA, Gamage S, Sarojini V (2017) Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides. J Control Rel 250:62–76. https://doi.org/10.1016/j.jconrel.2017.02.006 · DOI
  9. Dubikovskaya A, Thorne H, Pillow H, Contag H, Wender A (2008) Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters. Proc Natl Acad Sci 105(34):12128–12133. https://doi.org/10.1073/pnas.0805374105 · DOI
  10. Garg N, Singh B, Jain A, Nirbhavane P, Sharma R et al (2016) Fucose decorated solid-lipid nanocarriers mediate efficient delivery of methotrexate in breast cancer therapeutics. Colloids Surf B Biointerfaces 146:114–126. https://doi.org/10.1016/j.colsurfb.2016.05.051 · DOI
  11. Ghaz A, Abbaspour F, Anarjan N, Berenjian A, Jafarizadeh H (2015) Application of chitosan-based nanocarriers in tumor-targeted drug delivery. Mol Biotechnol 57(3):201–218. https://doi.org/10.1007/s12033-014-9816-3 · DOI
  12. Guidotti G, Brambilla L, Rossi D (2017) Cell-penetrating peptides: from basic research to clinics. Trends Pharmacol Sci 38(4):406–424. https://doi.org/10.1016/j.tips.2017.01.003 · DOI
  13. Guo Y, Zhao Y, Li R, Wang T, Han M et al (2016) Methotrexate nanoparticles prepared with codendrimer from polyamidoamine (PAMAM) and oligoethylene glycols (OEG) dendrons: antitumor efficacy in vitro and in vivo. Scientific Reports 6:28983. https://doi.org/10.1038/srep28983 · DOI
  14. Guterstam P, Madani F, Hirose H, Takeuchi T, Futaki S et al (2009) Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate. Biochim Biophys Acta 1788(12):2509–2517. https://doi.org/10.1016/j.bbamem.2009.09.014 · DOI
  15. Hutchinson J, Muller W (2000) Transgenic mouse models of human breast cancer. Oncogene 19(53):6130–6137. https://doi.org/10.1038/sj.onc.1203970 · DOI
  16. Joncour V, Laakkonen P (2018) Seek & Destroy, use of targeting peptides for cancer detection and drug delivery. Bioorg Med Chem 26(10):2797–2806. https://doi.org/10.1016/j.bmc.2017.08.052 · DOI
  17. Kebebe D, Liu Y, Wu Y, Vilakhamxay M, Liu Z et al (2018) Tumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers. Int J Nanomed 13:1425–1442. https://doi.org/10.2147/ijn.s156616 · DOI
  18. Kersemans V, Cornelissen B (2010) Targeting the tumour: cell penetrating peptides for molecular imaging and radiotherapy. Pharmaceuticals 3(3):600–620. https://doi.org/10.3390/ph3030600 · DOI
  19. Lee H, Dubikovskaya E, Hwang H, Semyonov A, Wang H et al (2008) Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells. J Am Chem Soc 130(29):9364–9370. https://doi.org/10.1021/ja710798b · DOI
  20. Lindgren M, Rosenthal-Aizman K, Saar K, Eiriksdottir E, Jiang Y et al (2006) Overcoming methotrexate resistance in breast cancer tumour cells by the use of a new cell-penetrating peptide. Biochem Pharmacol 71(4):416–425. https://doi.org/10.1016/j.bcp.2005.10.048 · DOI
  21. Ma DX, Qi XR (2010) Comparison of mechanisms and cellular uptake of cell-penetrating peptide on different cell lines. Yao Xue Xue Bao 45(9):1165–1169
  22. Madani F, Lindberg S, Langel L et al (2011) Mechanisms of cellular uptake of cell-penetrating peptides. J Biophys. https://doi.org/10.1155/2011/414729 · DOI
  23. Mäe M, Myrberg H, El-Andaloussi S (2009) Design of a tumor homing cell-penetrating peptide for drug delivery. Int J Pept Res Ther 15(11):11 · DOI
  24. Meikle S, Perugini V, Guildford AL, Santin M (2011) Synthesis, characterisation and in vitro anti-angiogenic potential of dendron VEGF blockers. Macromol Biosci 11(12):1761–1765. https://doi.org/10.1002/mabi.201100267 · DOI
  25. Merrifield RB (1965) Automated synthesis of peptides. Science 150(3693):178–185. https://doi.org/10.1126/science.150.3693.178 · DOI · Paper page
  26. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65(1–2):55–63 · DOI · Paper page
  27. Myrberg H, Zhang L, Mae M, Langel U (2008) Design of a tumor-homing cell-penetrating peptide. Bioconjug Chem 19(1):70–75. https://doi.org/10.1021/bc0701139 · DOI
  28. Najlah M, D’emanuele A (2006) Crossing cellular barriers using dendrimer nanotechnologies. Curr Opin Pharmacol 6(5):522–527. https://doi.org/10.1016/j.coph.2006.05.004 · DOI
  29. Park J, Ryu J, Kim K, Lee H, Bahn J et al (2002) Mutational analysis of a human immunodeficiency virus type 1 Tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J G Virol 83(5):1173–1181. https://doi.org/10.1099/0022-1317-83-5-1173 · DOI
  30. Perez E, Fernandez A (2015) Advanced targeted therapies in cancer: drug nanocarriers, the future of chemotherapy. Eur J Pharm Biopharm 93:52–79. https://doi.org/10.1016/j.ejpb.2015.03.018 · DOI
  31. Pilch J, Brown D, Komatsu M, Järvinen T, Yang M et al (2006) Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds. Proc Natl Acad Sci USA 103(8):2800–2804. https://doi.org/10.1073/pnas.0511219103 · DOI
  32. Ramsey D, Flynn H (2015) Cell-penetrating peptides transport therapeutics into cells. Pharmacol Ther 154:78–86. https://doi.org/10.1016/j.pharmthera.2015.07.003 · DOI
  33. Raucher D, Ryu J (2015) Cell-penetrating peptides: strategies for anticancer treatment. Trends Mol Med 21(9):560–570. https://doi.org/10.1016/j.molmed.2015.06.005 · DOI
  34. Regberg J, Srimanee A, Langel U (2012) Applications of cell-penetrating peptides for tumor targeting and future cancer therapies. Pharmaceuticals (Basel) 5(9):991–1007. https://doi.org/10.3390/ph5090991 · DOI
  35. Richard JP, Melikov K, Brooks H, Prevot P, Lebleu B et al (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 280(15):15300–15306. https://doi.org/10.1074/jbc.M401604200 · DOI
  36. Rodríguez H, Suarez M, Albericio F (2010) A convenient microwave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides. J Pep Sci 16(3):136–140. https://doi.org/10.1002/psc.1209 doi · DOI
  37. Ruoslahti E (2017) Tumor penetrating peptides for improved drug delivery. Adv Drug Deliv Rev 110–111:3–12. https://doi.org/10.1016/j.addr.2016.03.008 · DOI
  38. Shin M, Zhang J, Min K, Lee K, Byun Y et al (2014) Cell-penetrating peptides: achievements and challenges in application for cancer treatment. J Biomed Mater Res A 102(2):575–587. https://doi.org/10.1002/jbm.a.34859 · DOI
  39. Silverman R, Holladay M (2014) The organic chemistry of drug design and drug action, 3rd ed. Elsevier, Oxford
  40. Simberg D, Duza T, Park JH, Essler M, Pilch J et al (2007) Biomimetic amplification of nanoparticle homing to tumors. Proc Natl Acad Sci USA 104(3):932–936. https://doi.org/10.1073/pnas.0610298104 · DOI
  41. Soler M, Gonzalez-Bartulos M, Figueras E, Ribas X, Costas M et al (2015) Enzyme-triggered delivery of chlorambucil from conjugates based on the cell-penetrating peptide BP16. Org Biomol Chem 13(5):1470–1480. https://doi.org/10.1039/c4ob01875c · DOI
  42. Soriano D, Soler M, González-Bártulos M, Ribas X, Costas M et al (2014) Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. Org Biomol Chem 12(10):1652–1663. https://doi.org/10.1039/C3OB42422G · DOI
  43. Stanzl E, Trantow B, Vargas J, Wender P (2013) Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applications. Acc Chem Res 46(12):2944–2954. https://doi.org/10.1021/ar4000554 · DOI
  44. Torchilin V, Levchenko T, Rammohan R, Volodina N, Papahadjopoulos-Sternberg B et al (2003) Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes. Proc Natl Acad Sci USA 100(4):1972–1977. https://doi.org/10.1073/pnas.0435906100 · DOI
  45. Vargas JR, Stanzl EG, Teng NN, Wender PA (2014) Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance. Mol Pharm 11(8):2553–2565. https://doi.org/10.1021/mp500161z · DOI
  46. Vives E, Brodin P, Lebleu B (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 272(25):16010–16017 · DOI
  47. Wender P, Mitchell D, Pattabiraman K, Pelkey E, Steinman L et al (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci USA 97(24):13003–13008. https://doi.org/10.1073/pnas.97.24.13003 · DOI
  48. Xu L, Zhang H, Wu Y (2014) Dendrimer advances for the central nervous system delivery of therapeutics. ACS Chem Neurosci 5(1):2–13. https://doi.org/10.1021/cn400182z · DOI

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Metadata

Authors
Al-azzawi, S., & Masheta, D.
Venue
Journal of Pharmaceutical Investigation
Publisher
Springer Science and Business Media LLC
Published
2019-01-24
Volume
49
Issue
6
Pages
643-654
ISSN
  • 2093-5552
  • 2093-6214
DOI
10.1007/s40005-018-00424-w
Cited by
28
References
1
Language
en
Licence
www.springer.com/tdm (tdm)

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Al-azzawi, S., & Masheta, D. (2019). Designing a drug delivery system for improved tumor treatment and targeting by functionalization of a cell-penetrating peptide. Journal of Pharmaceutical Investigation. https://doi.org/10.1007/s40005-018-00424-w