Automated Synthesis of Peptides: Solid-phase peptide synthesis, a simple and rapid synthetic method, has now been automated.
Abstract
3949MetricsTotal Downloads394Last 6 Months53Last 12 Months104Total Citations9Last 6 Months0Last 12 Months1View all metrics
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Producing one kilogram of peptide would generate tons of chemical waste.
“In fact, it has been reported that producing just one kilogram of peptide would generate tons of chemical waste.13”
From Ynamide Coupling Reagents: Origin and Advances (2024) · cites this paper as [13]
Cited by
Sorted by citations
Principles that Govern the Folding of Protein Chains
Anfinsen, C. B. (1973) · Science · doi:10.1126/science.181.4096.223 · Cited by 7,096 · see citing works
Histones: At the Crossroads of Peptide and Protein Chemistry
Müller, M. M., & Muir, T. W. (2015) · Chemical Reviews · doi:10.1021/cr5003529 · Cited by 247 · see citing works
Ynamide Coupling Reagents: Origin and Advances
Hu, L., & Zhao, J. (2024) · Accounts of Chemical Research · doi:10.1021/acs.accounts.3c00743 · Cited by 89 · see citing works
- Authors
- Merrifield, R. B.
- Affiliations
- Rockefeller University (US)
- Corresponding author
- Merrifield, R. B.
- Venue
- Science
- Published
- 1965-10-08
- Volume
- 150
- Issue
- 3693
- Pages
- 178-185
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2018161329
- Cited by
- 540
- References
- 0
- Citations by year
- 2026: 8 · 2025: 23 · 2024: 17 · 2023: 21 · 2022: 18 · 2021: 12 · 2020: 10 · 2019: 12 · 2018: 14 · 2017: 10 · 2016: 2 · 2015: 7 · 2014: 12 · 2013: 12 · 2012: 8
- FWCI
- 7.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chemical Synthesis and Analysis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Structural Characterization
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Keywords
- peptide synthesis, automated synthesis
- MeSH terms
- Automation, Chemistry, Peptides, Chemical Phenomena
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
