The DOI matches its Crossref record; 21 of the 22 references it cites were found in a registry or an index.
Investigation of effect of non-ionic surfactant on preparation of griseofulvin non-aqueous nanoemulsion
Open accessAbstract
Generally emulsions are water-in-oil or oil-in-water type, but emulsions may contain polar liquid as one of the phase. Non-aqueous emulsions are useful in many situations where presence of water is not desirable, and formulation of active ingredients which undergo hydrolysis or oxidation in the presence of water. The study was to design a stable non-aqueous nanoemulsion (NANE) using cosmetically approved ingredients as a vehicle for the water-sensitive active ingredients. Non-aqueous nanoemulsion was designed to increase the dermal penetration and permeation and study solubility and dermal bioavailability of griseofulvin. For better compliance, the NANEs will be incorporated in cosmetics or personal care products. A non-aqueous system was obtained with glycerin and olive oil stabilized by glycerol monosterate with co-surfactant. It was observed that emulsification behavior is completely unpredictable and conventional theories of emulsification and HLB system cannot be applied here. An optimized NANE was obtained through implementation of pseudo-ternary phase diagram. Pseudo-ternary phase diagram was constructed using surfactant and co-surfactant ratio (1:1, 2:1, 3:1, 4:1) and nanoemulsion region was determined and further characterized for pH, rheology, globule size analysis, zeta potential and stability. Stability studies (agitation, centrifugation, freeze thaw cycle, accelerated stability) were carried out at 5, 25 and 40 °C. Cream was stable at 5 and 25. Results proved that NANE can be used as vehicle for the poorly water-soluble drug, suspension vehicles and oleogels.
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“Lecithin (phosphatidylcholine) [36], sodium deoxycholate (bile salt) [37], polyoxyethlene sorbitan monolaurate (Tween 20, 40, 60, 80) [38] and sorbitan monolaurate (Span 20, 40, 60, 80) [39] are commonly employed in the preparation of NEs. Other surfactants proposed are poloxamers [40], sodium dodecyl sulfate [41], amphiphilic proteins like casein [42], polysaccharides (starch derivatives, gums) [”
From Nanoemulsions for “Nose-to-Brain” Drug Delivery (2019) · cites this paper as [39]
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Microemulsion-based media as novel drug delivery systems
Lawrence, M. J., & Rees, G. D. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00103-4 · Cited by 2,044
Pharmaceutics : the science of dosage form design
Aulton, M. E. (2002) · Churchill Livingstone eBooks · Cited by 1,329
Microemulsions: A Potential Drug Delivery System
Ghosh, P., & Murthy, R. (2006) · Current Drug Delivery · doi:10.2174/156720106776359168 · Cited by 232
Aggarwal, N., Goindi, S., & Khurana, R. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.01.004 · Cited by 109
Stability of Nonaqueous Emulsions
Imhof, A., & Pine, D. J. (1997) · Journal of Colloid and Interface Science · doi:10.1006/jcis.1997.5020 · Cited by 83
Rheological responses of oil-in-oil emulsions in an electric field
Ha, J., & Yang, S. (2000) · Journal of Rheology · doi:10.1122/1.551084 · Cited by 72
Non-aqueous high internal phase emulsions. Preparation and stability
Cameron, N. R., & Sherrington, D. C. (1996) · Journal of the Chemical Society Faraday Transactions · doi:10.1039/ft9969201543 · Cited by 61
Novel anhydrous emulsions: Formulation as controlled release vehicles
Suitthimeathegorn, O., Jaitely, V., & Florence, A. T. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.03.028 · Cited by 42
Intramuscular absorption and biodistribution of dexamethasone from non-aqueous emulsions in the rat
Suitthimeathegorn, O., Turton, J. A., MIZUUCHI, H., & Florence, A. T. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.11.062 · Cited by 33
Voigt, M., Koerber, M., & Bodmeier, R. A. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.05.029 · Cited by 28
Research works printed but not linked: 9
- Suitthimeathegorn, O., Jaitely, V., Florence, A.T.: Exploring the possibilities of stable anhydrous emulsions. Adv. Drug Deliv. Rev. 4(5), 5–10 (2008)
- Sakthivel, T., Wan, K.W., Florence, A.T.: Formulation of nonaqueous emulsions. Pharm. Sci. 1(Suppl 1), 681–685 (1999)
- Patel, P., Monpara, M.: Formulation and evaluation of microemulsion based gel of itraconazole. Pharmagene. 1(2), 32–36 (2013)
- Moghimipour, E.: Permeability assessment of griseofulvin microemulsion through rat skin. Int. J. Pharm. Chem. Bio. Sci. 3(4), 1061–1065 (2013)
- Jadhav, C., Kate, V.K., Payghan, S. A.: Formulation and evaluation of antifungal non-aqueous microemulsion for topical drug delivery of griseofulvin. Inventi Rapid. 2014 (4), 1–13 (2014)
- Payghan. S.A., Mane, Y.V., Kate, V.K., Tamboli, Z.J.: Anhydrous emulsion: vehicles for topical delivery of ketoconazole. Inventi Rapid. 2014(4), 1–11(2014)
- Payghan, S.A., Kate, V.K., Purohit, S., Bhandari, A.: Goodness of fit model dependent approach for release kinetics and in vitro release of piroxicam from PEGS based non aqueous emulsion. Inventi Rapid 2012(3), 1–8 (2012)
- Payghan, S.A., Kate, V.K., Purohit, S., Bhandari, A.: Effect of aging conditions on the dissolution and diffusion stability of non aqueous emulsion. Inventi Rapid 3, 1–7 (2012)
- Jadhav, C.M., Kate, V.K., Payghan, S.A.: Formulation and evaluation of antifungal non-aqueous microemulsion for topical drug delivery of griseofulvin. Inventi Rapid 2014(4), 1–13 (2014)
Cited by
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Nanoemulsion: Concepts, development and applications in drug delivery
Singh, Y., Meher, J. G., Raval, K., Khan, F. A., Chaurasia, M., Jain, N. K., & Chourasia, M. K. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.03.008 · Cited by 1,358
Nanoemulsions for “Nose-to-Brain” Drug Delivery
Bonferoni, M. C., Rossi, S., Sandri, G., Ferrari, F., Gavini, E., Rassu, G., & Giunchedi, P. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11020084 · Cited by 269
Safaya, M., & Rotliwala, Y. C. (2019) · Materials Today Proceedings · doi:10.1016/j.matpr.2019.11.267 · Cited by 143
Dye‐Loaded Nanoemulsions: Biomimetic Fluorescent Nanocarriers for Bioimaging and Nanomedicine
Klymchenko, A. S., Liu, F., Collot, M., & Anton, N. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202001289 · Cited by 103
Bashir, M., Ahmad, J., Asif, M., Khan, S.-U.-D., Irfan, M., Ibrahim, A. Y., Asghar, S., Khan, I. U., Iqbal, M. S., Haseeb, A., et al. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s294653 · Cited by 76
Metadata
- Authors
- Jadhav, C., Kate, V., & Payghan, S. A.
- Corresponding author
- Payghan, Santosh A.
- ORCID
- Payghan, Santosh A.
- Venue
- Journal of nanostructure in chemistry
- Published
- 2014-12-18
- Volume
- 5
- Issue
- 1
- Pages
- 107-113
- ISSN
- 2008-9244 (ISSN-L)
- 2193-8865
- OpenAlex
- W2068504124
- Cited by
- 78
- References
- 22
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 11 · 2023: 7 · 2022: 9 · 2021: 12 · 2020: 6 · 2019: 7 · 2018: 6 · 2017: 5 · 2016: 8 · 2015: 2
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of nanostructure in chemistry (publishedVersion, cc-by)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Surfactants and Colloidal Systems
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
- Keywords
- griseofulvin, nonionic surfactants, glyceryl monostearate, pseudo-ternary phase diagram, emulsion stability, skin penetration, poorly water-soluble drugs, emulsification, rheology, zeta potential, globule size, cosmetic formulation, personal care products
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