Graphene and graphene oxide as nanomaterials for medicine and biology application
Open accessAbstract
Graphene- and graphene oxide-based nanomaterials have gained broad interests in research because of their unique physiochemical properties. The 2D allotropic structure allows it to be used in various biological fields. The biomedical applications of graphene and its composite include its use in gene and small molecular drug delivery. It is further used for biofunctionalization of protein, in anticancer therapy, as an antimicrobial agent for bone and teeth implantation. The biocompatibility of the newly synthesized nanomaterials allows its substantial use in medicine and biology. The current review summarizes the chemical structure and biological application of graphene in various fields.
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NGOs are biocompatible and have immunomodulatory effects.
“Owing to their biocompatibility and immunomodulatory effects, significant progress has been made in adopting NGOs for biomedical purposes23,24.”
From Bioengineered liver crosslinked with nano-graphene oxide enables efficient liver regeneration via MMP suppression and immunomodulation (2023) · cites this paper as [24]
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“Moreover, the degradation of these materials may cause induction of an autocatalytic ester breakdown that lowers the pH, which is not suitable for cell viability [129, 130].”
BackgroundUsing Graphene Oxide High Near‐Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
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Kim, D.-H., Kim, M.-J., Kwak, S.-Y., Jeong, J., Choi, D., Choi, S. W., Ryu, J., & Kang, K.-S. (2023) · Nature Communications · doi:10.1038/s41467-023-35941-2 · Cited by 53 · see citing works
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- Authors
- Priyadarsini, S., Mohanty, S., Mukherjee, S., Basu, S., & Mishra, M.
- Affiliations
- National Institute of Technology Rourkela (IN)
- Biju Patnaik University of Technology (IN)
- Corresponding author
- Mishra, Monalisa
- Venue
- Journal of Nanostructure in Chemistry
- Published
- 2018-06
- Volume
- 8
- Issue
- 2
- Pages
- 123-137
- ISSN
- 2008-9244 (ISSN-L)
- 2193-8865
- OpenAlex
- W2805157846
- Cited by
- 570
- References
- 4
- Citations by year
- 2026: 37 · 2025: 61 · 2024: 91 · 2023: 104 · 2022: 106 · 2021: 87 · 2020: 54 · 2019: 27 · 2018: 3
- FWCI
- 17.11
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of nanostructure in chemistry (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Department of Biotechnology , Ministry of Science and Technology (BT/PR21857/NNT/28/1238/2017)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Graphene and Nanomaterials Applications
- Physical Sciences › Materials Science › Materials Chemistry › Graphene research and applications
- Physical Sciences › Engineering › Biomedical Engineering › Nanotechnology research and applications
- Keywords
- graphene, graphene oxide, nanomaterials, biomedical applications, drug delivery, gene delivery, cancer therapy, antimicrobial agents, biocompatibility, two-dimensional materials
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