Using Graphene Oxide High Near‐Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
Abstract
A novel strategy to dissociate amyloid aggregation is presented, using localised heat generation from a clinically used amyloid staining dye, thioflavin-S (ThS)-modified graphene oxide (GO) under NIR laser irradiation. Compared to traditional chemotherapies, photothermal therapy shows reduced side effects and improved selectivity and safety.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The second approach-external stimulus-triggered mode switching-employs graphene oxide functionalized with thioflavin-S.
“The second approach—external stimulus-triggered mode switching—employs graphene oxide functionalized with thioflavin-S (ThS).”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
Continuous diagnostics enable real-time efficacy monitoring while minimizing systemic toxicity.
“Continuous diagnostics enable real-time efficacy monitoring while minimizing systemic toxicity [30].”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
ThS specifically binds amyloid fibrils and fluoresces, providing continuous diagnostic signaling.
“ThS specifically binds amyloid fibrils and fluoresces, providing continuous diagnostic signaling.”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
Therapeutic action activates via NIR irradiation: graphene oxide absorbs NIR light, generating localized heat to disassemble fibrils.
“Therapeutic action activates via near-infrared (NIR) irradiation: graphene oxide absorbs NIR light, generating localized heat to disassemble fibrils.”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
Cites
Preparation of Graphitic Oxide
Hummers, W. S., & Offeman, R. E. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01539a017 · Cited by 29,962 · see citing works
Alzheimer's Disease: Genes, Proteins, and Therapy
Selkoe, D. J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.741 · Cited by 6,063 · see citing works
Preparation and characterization of graphene oxide paper
Dikin, D. A., Stankovich, S., Zimney, E. J., Piner, R. D., Dommett, G., Evmenenko, G., Nguyen, S. T., & Ruoff, R. S. (2007) · Nature · doi:10.1038/nature06016 · Cited by 5,582 · see citing works
Chemically Derived, Ultrasmooth Graphene Nanoribbon Semiconductors
Li, X., Wang, X., Zhang, L., Lee, S., & Dai, H. (2008) · Science · doi:10.1126/science.1150878 · Cited by 4,796 · see citing works
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Hirsch, L. R., Stafford, R. J., Bankson, J. A., Sershen, S. R., Rivera, B., Price, R. E., Hazle, J. D., Halas, N. J., & West, J. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2232479100 · Cited by 3,961 · see citing works
PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs
Liu, Z., Robinson, J. T., Sun, X., & Dai, H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja803688x · Cited by 3,593 · see citing works
Nano-graphene oxide for cellular imaging and drug delivery
Sun, X., Liu, Z., Welsher, K., Robinson, J. T., Goodwin, A. P., Zaric, S., & Dai, H. (2008) · Nano Research · doi:10.1007/s12274-008-8021-8 · Cited by 3,296 · see citing works
Kovtyukhova, N. I., Ollivier, P. J., Martin, B. R., Mallouk, T. E., Чижик, С. А., Buzaneva, E. V., & Gorchinskiy, A. (1999) · Chemistry of Materials · doi:10.1021/cm981085u · Cited by 3,247 · see citing works
Blennow, K., de Leon, M. J., & Zetterberg, H. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69113-7 · Cited by 3,134 · see citing works
Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy
Yang, K., Zhang, S., Zhang, G., Sun, X., Lee, S., & Liu, Z. (2010) · Nano Letters · doi:10.1021/nl100996u · Cited by 2,406 · see citing works
Kam, N. W. S., O’Connell, M. J., Wisdom, J. A., & Dai, H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502680102 · Cited by 2,300 · see citing works
Graphene/Polyaniline Nanofiber Composites as Supercapacitor Electrodes
Zhang, K., Zhang, L., Zhao, X., & Wu, J. (2010) · Chemistry of Materials · doi:10.1021/cm902876u · Cited by 2,238 · see citing works
Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy
Robinson, J. T., Tabakman, S. M., Liang, Y., Wang, H., Casalongue, H. S., Vinh, D., & Dai, H. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2010175 · Cited by 2,099 · see citing works
Hyperthermia in combined treatment of cancer
Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H. B., FELIX, R., & Schlag, P. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00818-5 · Cited by 2,002 · see citing works
Gaggelli, E., Kozlowski, H., Valensin, D., & Valensin, G. (2006) · Chemical Reviews · doi:10.1021/cr040410w · Cited by 1,729 · see citing works
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
Ehrnhoefer, D. E., Bieschke, J., Boeddrich, A., Herbst, M., Masino, L., Lurz, R., Engemann, S., Pastore, A., & Wanker, E. (2008) · Nature Structural &Molecular Biology · doi:10.1038/nsmb.1437 · Cited by 1,424 · see citing works
Computationally Guided Photothermal Tumor Therapy Using Long-Circulating Gold Nanorod Antennas
von Maltzahn, G., Park, J., Agrawal, A., Bandaru, N. K., Das, S. K., Sailor, M. J., & Bhatia, S. N. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4242 · Cited by 1,047 · see citing works
In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis
Stine, W. B., Dahlgren, K. N., Krafft, G. A., & LaDu, M. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210207200 · Cited by 1,015 · see citing works
Serio, T., Cashikar, A., Kowal, A., Sawicki, G., Moslehi, J., Serpell, L., Arnsdorf, M., & Lindquist, S. (2000) · Science · doi:10.1126/science.289.5483.1317 · Cited by 988 · see citing works
Soto, C. A., Sigurdsson, E. M., Morelli, L., Kumar, R., Castaño, E. M., & Frangione, B. (1998) · Nature Medicine · doi:10.1038/nm0798-822 · Cited by 877 · see citing works
Alzheimer's Disease: From Pathology to Therapeutic Approaches
Jakob‐Roetne, R., & Jacobsen, H. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200802808 · Cited by 626 · see citing works
Hyperthermic Effects of Gold Nanorods on Tumor Cells
Huff, T. B., Tong, L., Zhao, Y., Hansen, M., Cheng, J., & Wei, A. (2007) · Nanomedicine · doi:10.2217/17435889.2.1.125 · Cited by 568 · see citing works
Marković, Z. M., Harhaji-Trajkovic, L. M., Marković, B. M. T., Kepić, D., Arsikin, K. M., Jovanović, S., Pantovic, A., Dramićanin, M. D., & Trajković, V. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.10.030 · Cited by 560 · see citing works
Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles
Cabaleiro-Lago, C., Quinlan-Pluck, F., Lynch, I., Lindman, S., Minogue, A. M., Thulin, E., Walsh, D. M., Dawson, K. A., & Linse, S. S. (2008) · Journal of the American Chemical Society · doi:10.1021/ja8041806 · Cited by 547 · see citing works
Feng, L., Chen, Y., Ren, J., & Qu, X. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.01.002 · Cited by 476 · see citing works
Self-citationThe effect of macromolecular crowding on protein aggregation and amyloid fibril formation
Munishkina, L. A., Cooper, E. M., Uversky, V. N., & Fink, A. L. (2004) · Journal of Molecular Recognition · doi:10.1002/jmr.699 · Cited by 352 · see citing works
Scott, L. E., & Orvig, C. (2009) · Chemical Reviews · doi:10.1021/cr9000176 · Cited by 332 · see citing works
Nanoparticle-Mediated Local and Remote Manipulation of Protein Aggregation
Kogan, M. J., Bastús, N. G., Amigo, R., Grillo‐Bosch, D., Araya, E., Turiel, A., Labarta, A., Giralt, E., & Puntes, V. (2005) · Nano Letters · doi:10.1021/nl0516862 · Cited by 322 · see citing works
Yoo, S. I., Yang, M., Brender, J., Vivekanandan, S., Sun, K., Joo, N. E., Jeong, S., Ramamoorthy, A., & Kotov, N. A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007824 · Cited by 268 · see citing works
Zhang, P., Hong, Z., Yu, T., Chen, X., & Jing, X. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.08.041 · Cited by 268 · see citing works
Ghosh, S., Dutta, S., Gomes, E., Carroll, D., D’Agostino, R., Olson, J. D., Guthold, M., & Gmeiner, W. H. (2009) · ACS Nano · doi:10.1021/nn900368b · Cited by 260 · see citing works
Geng, J., Li, M., Ren, J., Wang, E., & Qu, X. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007067 · Cited by 238 · see citing works
Self-citationUrbanc, B., Cruz, L., Le, R., Sanders, J., Ashe, K. H., Duff, K., Stanley, H. E., Irizarry, M. C., & Hyman, B. T. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222433299 · Cited by 237 · see citing works
Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease
Barnham, K. J., Kenche, V. B., Ciccotosto, G. D., Smith, D. P., Tew, D. J., Liu, X., Perez, K. A., Cranston, G. A., Johanssen, T., Volitakis, I., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800712105 · Cited by 210 · see citing works
Song, Y., Chen, Y., Feng, L., Ren, J., & Qu, X. (2011) · Chemical Communications · doi:10.1039/c0cc05533f · Cited by 181 · see citing works
Self-citationFilamentous phage as vector-mediated antibody delivery to the brain
Frenkel, D., & Solomon, B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072027199 · Cited by 178 · see citing works
Foguel, D., Suarez, M. C., Gonzales, A. D. F., Porto, T. C. R., Palmieri, L. D. C., Einsiedler, C. M., de Andrade, L. R., Lashuel, H. A., Lansbury, P. T., Kelly, J. W., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1734009100 · Cited by 177 · see citing works
Barten, D. M., Guss, V. L., Corsa, J. A., Loo, A., Hansel, S. B., Zheng, M., Munoz, B., Srinivasan, K., Wang, B., Robertson, B. J., et al. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.075408 · Cited by 159 · see citing works
Frydman‐Marom, A., Rechter, M., Shefler, I., Bram, Y., Shalev, D. E., & Gazit, E. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200802123 · Cited by 145 · see citing works
Gursky, O., & Aleshkov, S. B. (2000) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(99)00228-9 · Cited by 140 · see citing works
Wang, X., Wang, C., Qu, K., Song, Y., Ren, J., Miyoshi, D., Sugimoto, N., & Qu, X. (2010) · Advanced Functional Materials · doi:10.1002/adfm.201001118 · Cited by 131 · see citing works
Self-citationWang, X., Wang, C., Qu, K., Song, Y., Ren, J., Miyoshi, D., Sugimoto, N., & Qu, X. (2010) · Advanced Functional Materials · doi:10.1002/adfm.201090103 · Cited by 121 · see citing works
Self-citationAmyloid β -Protein Assembly as a Therapeutic Target of Alzheimers Disease
Yamin, G., Ono, K., Inayathullah, M., & Teplow, D. B. (2008) · Current Pharmaceutical Design · doi:10.2174/138161208786404137 · Cited by 111 · see citing works
Shuttle‐Mediated Drug Delivery to the Brain
Malakoutikhah, M., Teixidò, M., & Giralt, E. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201006565 · Cited by 85 · see citing works
Ouberai, M. M., Dumy, P., Chierici, S., & Garcia, J. (2009) · Bioconjugate Chemistry · doi:10.1021/bc900281b · Cited by 61 · see citing works
Characteristics of the binding of thioflavin S to tau paired helical filaments
Santa‐María, I., Pérez, M., Hernández, F., Ávila, J., & Moreno, F. J. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-9307 · Cited by 53 · see citing works
Polymerization of human prion peptide HuPrP 106–126 to amyloid in nucleic acid solution
Nandi, P. (1998) · Archives of Virology · doi:10.1007/s007050050373 · Cited by 43 · see citing works
Boshuizen, R. S., Langeveld, J., Salmona, M., Williams, A., Meloen, R. H., & Langedijk, J. P. M. (2004) · Analytical Biochemistry · doi:10.1016/j.ab.2004.06.011 · Cited by 25 · see citing works
Flagged first, then by citations
1 of the 49 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
Huang, Y., Ren, J., & Qu, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00672 · Cited by 3,565 · see citing works
Self-citationFunctional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,432 · see citing works
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
Hong, G., Diao, S., Antaris, A. L., & Dai, H. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00008 · Cited by 1,394 · see citing works
Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents
Sun, Z., Xie, H., Tang, S., Yu, X., Guo, Z., Shao, J., Zhang, H., Huang, H., Wang, H., & Chu, P. K.-H. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201506154 · Cited by 1,135 · see citing works
Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy
Shao, J., Xie, H., Huang, H., Li, Z., Sun, Z., Xu, Y., Xiao, Q., Yu, X., Zhao, Y., Zhang, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms12967 · Cited by 1,012 · see citing works
Recent Advances in Nanozyme Research
Wang, H., Wan, K., & Shi, X. (2018) · Advanced Materials · doi:10.1002/adma.201805368 · Cited by 979 · see citing works
Two-dimensional graphene analogues for biomedical applications
Chen, Y., Tan, C., Zhang, H., & Wang, L. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00300d · Cited by 897 · see citing works
Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents
Sun, Z., Xie, H., Tang, S., Yu, X., Guo, Z., Shao, J., Zhang, H., Huang, H., Wang, H., & Chu, P. K.-H. (2015) · Angewandte Chemie · doi:10.1002/ange.201506154 · Cited by 881 · see citing works
Qiu, M., Wang, D., Liang, W., Liu, L., Zhang, Y., Chen, X., Sang, D. K., Xing, C., Li, Z., Dong, B., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1714421115 · Cited by 814 · see citing works
Nguyen, P. H., Ramamoorthy, A., Sahoo, B. R., Zheng, J., Faller, P., Straub, J. E., Domı́nguez, L., Shea, J., Dokholyan, N. V., Simone, A. D., et al. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01122 · Cited by 676 · see citing works
Self-citationHan, L., Lu, X., Wang, M., Gan, D., Deng, W., Wang, K., Fang, L., Liu, K., Chan, C. W., Tang, Y., et al. (2017) · Small · doi:10.1002/smll.201601916 · Cited by 699 · see citing works
Graphene based materials for biomedical applications
Yang, Y., Asiri, A. M., Tang, Z., Du, D., & Lin, Y. (2013) · Materials Today · doi:10.1016/j.mattod.2013.09.004 · Cited by 653 · see citing works
New Horizons for Diagnostics and Therapeutic Applications of Graphene and Graphene Oxide
Feng, L., Wu, L. J., & Qu, X. (2012) · Advanced Materials · doi:10.1002/adma.201203229 · Cited by 633 · see citing works
Self-citationComparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatment
Wang, Y., Black, K. C. L., Luehmann, H. P., Li, W., Zhang, Y. S., Cai, X., Wan, D., Liu, S.-Y., Li, M., Kim, P. M., et al. (2013) · ACS Nano · doi:10.1021/nn304332s · Cited by 616 · see citing works
Self-citationGraphene oxide for photonics, electronics and optoelectronics
Wu, J., Lin, H., Moss, D., Loh, K. P., & Jia, B. (2023) · Nature Reviews Chemistry · doi:10.1038/s41570-022-00458-7 · Cited by 622 · see citing works
Graphene and graphene oxide as nanomaterials for medicine and biology application
Priyadarsini, S., Mohanty, S., Mukherjee, S., Basu, S., & Mishra, M. (2018) · Journal of Nanostructure in Chemistry · doi:10.1007/s40097-018-0265-6 · Cited by 570 · see citing works
Antibacterial applications of graphene-based nanomaterials: Recent achievements and challenges
Ji, H., Sun, H., & Qu, X. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.009 · Cited by 553 · see citing works
Self-citationWang, Y., Wang, K., Zhao, J., Liu, X., Bu, J., Yan, X., & Huang, R. (2013) · Journal of the American Chemical Society · doi:10.1021/ja312221g · Cited by 528 · see citing works
Liu, T., Zhang, M., Liu, W., Zeng, X., Song, X., Yang, X., Zhang, X., & Feng, J. X. (2018) · ACS Nano · doi:10.1021/acsnano.8b01456 · Cited by 517 · see citing works
Self-citationInorganic nanomaterials with rapid clearance for biomedical applications
Wang, X., Zhong, X., Li, J., Liu, Z., & Cheng, L. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00461h · Cited by 509 · see citing works
Functionalized graphene nanocomposites for enhancing photothermal therapy in tumor treatment
Chen, Y., Su, Y.-L., Hu, S., & Chen, S. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.05.022 · Cited by 468 · see citing works
Piao, J., Wang, L., Gao, F., You, Y., Xiong, Y., & Yang, L. (2014) · ACS Nano · doi:10.1021/nn503779d · Cited by 427 · see citing works
Wu, X., Chen, G. Y., Owens, G., Chu, D., & Xu, H. (2019) · Materials Today Energy · doi:10.1016/j.mtener.2019.02.001 · Cited by 420 · see citing works
Electrically Controlled Drug Delivery from Graphene Oxide Nanocomposite Films
Weaver, C. L., LaRosa, J. M., Luo, X., & Cui, X. T. (2014) · ACS Nano · doi:10.1021/nn406223e · Cited by 421 · see citing works
Kim, H., Lee, D., Kim, J., Kim, T.-I., & Kim, W. J. (2013) · ACS Nano · doi:10.1021/nn403096s · Cited by 420 · see citing works
Feng, L., Yang, X., Shi, X., Tan, X., Peng, R., Wang, J., & Liu, Z. (2013) · Small · doi:10.1002/smll.201202538 · Cited by 414 · see citing works
Self-citationChen, Z., Wang, Q., Wang, H., Zhang, L., Song, G., Song, L., Hu, J., Wang, H., Liu, J., Zhu, M., et al. (2013) · Advanced Materials · doi:10.1002/adma.201204616 · Cited by 377 · see citing works
Oriented collagen fibers direct tumor cell intravasation
Han, W., Chen, S., Yuan, W., Fan, Q., Tian, J., Wang, X., Chen, L., Zhang, X., Wei, W., Liu, R., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1610347113 · Cited by 376 · see citing works
Wang, Y., Wang, H., Liu, D., Song, S., Wang, X., & Zhang, H. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.06.045 · Cited by 373 · see citing works
Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering
Zhao, H., Ding, R., Zhao, X., Li, Y., Qu, L., Pei, H., Yildirimer, L., Wu, Z., & Zhang, W. (2017) · Drug Discovery Today · doi:10.1016/j.drudis.2017.04.002 · Cited by 336 · see citing works
Graphene‐Based Smart Platforms for Combined Cancer Therapy
Gu, Z., Zhu, S., Yan, L., Zhao, F., & Zhao, Y. (2018) · Advanced Materials · doi:10.1002/adma.201800662 · Cited by 334 · see citing works
Pan, S., Yin, J., Yu, L., Zhang, C., Zhu, Y., Gao, Y., & Chen, Y. (2019) · Advanced Science · doi:10.1002/advs.201901511 · Cited by 319 · see citing works
Near-infrared light control of bone regeneration with biodegradable photothermal osteoimplant
Tong, L., Liao, Q., Zhao, Y., Huang, H., Gao, A., Zhang, W., Gao, X., Wei, W., Guan, M., Chu, P. K.-H., et al. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.12.008 · Cited by 305 · see citing works
Small gold nanorods laden macrophages for enhanced tumor coverage in photothermal therapy
Li, Z., Huang, H., Tang, S., Li, Y., Yu, X., Wang, H., Li, P., Sun, Z., Zhang, H., Liu, C., et al. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.09.038 · Cited by 282 · see citing works
Song, X., Gong, H., Yin, S., Cheng, L., Wang, C., Li, Z., Li, Y., Wang, X., Liu, G., & Liu, Z. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201302463 · Cited by 281 · see citing works
Photothermal Contribution to Enhanced Photocatalytic Performance of Graphene-Based Nanocomposites
Gan, Z., Wu, X., Meng, M., Zhu, X., Yang, L., & Chu, P. K.-H. (2014) · ACS Nano · doi:10.1021/nn503249c · Cited by 280 · see citing works
Qu, G., Xia, T., Zhou, W., Zhang, X., Zhang, H., Hu, L., Shi, J., Yu, X., & Jiang, G. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00445 · Cited by 276 · see citing works
Multifunctional phototheranostic nanomedicine for cancer imaging and treatment
Gao, D., Guo, X., Zhang, X., Chen, S., Wang, Y., Chen, T., Huang, G. J., Gao, Y. F., Tian, Z., & Yang, Z. (2019) · Materials Today Bio · doi:10.1016/j.mtbio.2019.100035 · Cited by 274 · see citing works
Photothermally Controlled Gene Delivery by Reduced Graphene Oxide–Polyethylenimine Nanocomposite
Kim, H., & Kim, W. J. (2013) · Small · doi:10.1002/smll.201202636 · Cited by 274 · see citing works
Graphene-based nanomaterials and their potentials in advanced drug delivery and cancer therapy
Liu, J., Dong, J. Y., Zhang, T., & Peng, Q. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.07.034 · Cited by 273 · see citing works
Yu, J. X., Yang, C., Li, J., Ding, Y., Zhang, L., Yousaf, M. Z., Lin, J., Pang, R., Wei, L., Xu, L., et al. (2014) · Advanced Materials · doi:10.1002/adma.201305811 · Cited by 254 · see citing works
NIR‐Laser‐Switched In Vivo Smart Nanocapsules for Synergic Photothermal and Chemotherapy of Tumors
Meng, Z., Wei, F., Wang, R., Xia, M., Chen, Z., Wang, H.-P., & Zhu, M. (2015) · Advanced Materials · doi:10.1002/adma.201502669 · Cited by 252 · see citing works
Zhang, C., Bu, W., Ni, D., Zuo, C., Cheng, C., Li, Q., Zhang, L., Wang, Z., & Shi, J. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b03375 · Cited by 248 · see citing works
Near-infrared light-responsive inorganic nanomaterials for photothermal therapy
Bao, Z., LIU, X.-R., Liu, Y., Liu, H., & Zhao, K. (2016) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2015.11.123 · Cited by 247 · see citing works
Qi, J., Fang, Y., Kwok, R. T. K., Zhang, X., Hu, X., Lam, J. W. Y., Ding, D., & Tang, B. Z. (2017) · ACS Nano · doi:10.1021/acsnano.7b03062 · Cited by 246 · see citing works
Sun, H., Wu, L. J., Gao, N., Ren, J., & Qu, X. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am3030849 · Cited by 243 · see citing works
Self-citationXing, C., Jing, G., Liang, X. M., Qiu, M., Li, Z., Cao, R., Li, X., Fan, D., & Zhang, H. (2017) · Nanoscale · doi:10.1039/c7nr00663b · Cited by 234 · see citing works
Near-infrared fluorescent probes in cancer imaging and therapy: an emerging field
Yi, X., Wang, F., Qin, W., Yang, X., & Yuan, J. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s60206 · Cited by 233 · see citing works
Self-citationWang, W., Wang, L., Li, Y., Liu, S., Xie, Z., & Jing, X. (2016) · Advanced Materials · doi:10.1002/adma.201602997 · Cited by 232 · see citing works
Li, Y., Feng, L., Shi, X., Wang, X., Yang, Y., Yang, K., Liu, T., Yang, G., & Liu, Z. (2013) · Small · doi:10.1002/smll.201303234 · Cited by 231 · see citing works
Carbon nanostructures as multi-functional drug delivery platforms
Mendes, R. G., Bachmatiuk, A., Büchner, B., Cuniberti, G., & Rümmeli, M. H. (2012) · Journal of Materials Chemistry B · doi:10.1039/c2tb00085g · Cited by 229 · see citing works
Sun, T., Dou, J., Liu, S., Wang, X., Zheng, X., Wang, Y., Pei, J., & Xie, Z. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b01458 · Cited by 222 · see citing works
DNA metallization: principles, methods, structures, and applications.
Chen, Z., Liu, C.-Q., Cao, F.-F., Ren, J.-S., & Qu, X.-G. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00011e · Cited by 118 · see citing works
Self-citationCarbon-based nanozymes for biomedical applications
Ding, H., Hu, B., Zhang, B., Zhang, H., Yan, X., Nie, G., & Liang, M. (2020) · Nano Research · doi:10.1007/s12274-020-3053-9 · Cited by 220 · see citing works
Two-dimensional TiS 2 nanosheets for in vivo photoacoustic imaging and photothermal cancer therapy
Qian, X., Shen, S., Liu, T., Cheng, L., & Liu, Z. (2015) · Nanoscale · doi:10.1039/c5nr00893j · Cited by 219 · see citing works
Availability of the Basal Planes of Graphene Oxide Determines Whether It Is Antibacterial
Hui, L., Piao, J., Auletta, J. T., Hu, K., Zhu, Y., Meyer, T. Y., Liu, H., & Yang, L. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am503070z · Cited by 216 · see citing works
Li, W., Wang, J., Ren, J., & Qu, X. (2013) · Advanced Materials · doi:10.1002/adma.201302810 · Cited by 215 · see citing works
Self-citationBiomedical Applications of Graphene Nanomaterials and Beyond
Ghosal, K., & Sarkar, K. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00376 · Cited by 213 · see citing works
Song, G., Wang, Q., Wang, Y., Lv, G., Li, C., Zou, R., Chen, Z., Qin, Z., Huo, K., Hu, R., et al. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201203317 · Cited by 212 · see citing works
Fluorescent Diagnostic Probes in Neurodegenerative Diseases
Zhou, J., Jangili, P., Son, S., Ji, M. S., Won, M., & Kim, J. S. (2020) · Advanced Materials · doi:10.1002/adma.202001945 · Cited by 203 · see citing works
Functionalization of Graphene Oxide and its Biomedical Applications
Nanda, S. S., Papaefthymiou, G. C., & Yi, D. K. (2015) · Critical reviews in solid state and materials sciences/CRC critical reviews in solid state and materials sciences · doi:10.1080/10408436.2014.1002604 · Cited by 202 · see citing works
Yin, F., Hu, K., Chen, Y., Yu, M., Wang, D., Wang, Q., Yong, K., Lu, F., Liang, Y., & Li, Z. (2017) · Theranostics · doi:10.7150/thno.17841 · Cited by 201 · see citing works
Chen, F., Hableel, G., Zhao, E. R., & Jokerst, J. V. (2018) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2018.02.053 · Cited by 199 · see citing works
Yin, T., Yang, L., Liu, Y., Zhou, X., Sun, J., & Liu, J. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.06.035 · Cited by 198 · see citing works
Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review
Feng, S., Zhang, X., Shi, D., & Wang, Z. (2020) · Frontiers of Chemical Science and Engineering · doi:10.1007/s11705-020-1927-8 · Cited by 197 · see citing works
Ren, C., Hu, X., & Zhou, Q. (2018) · Advanced Science · doi:10.1002/advs.201700595 · Cited by 195 · see citing works
Yang, Q., Yin, H., Xu, T., Zhu, D., Yin, J., Chen, Y., Yu, X., Gao, J., Zhang, C., Chen, Y., et al. (2020) · Small · doi:10.1002/smll.201906814 · Cited by 195 · see citing works
Trusovas, R., Račiukaitis, G., Niaura, G., Barkauskas, J., Valušis, G., & Pauliukaitė, R. (2015) · Advanced Optical Materials · doi:10.1002/adom.201500469 · Cited by 193 · see citing works
Graphene-Based Nanomaterials: Biological and Medical Applications and Toxicity
Tonelli, F. M. P., Goulart, V. A. M., Gomes, K. N., Ladeira, M. S., Santos, A. K., Lorençon, E., Ladeira, L. O., & Resende, R. R. (2015) · Nanomedicine · doi:10.2217/nnm.15.65 · Cited by 191 · see citing works
Mechanism of Photoluminescence from Chemically Derived Graphene Oxide: Role of Chemical Reduction
Gan, Z., Xiong, S., Wu, X., Xu, T., Zhu, X., Gan, X., Guo, J., Shen, J., Sun, L., & Chu, P. K.-H. (2013) · Advanced Optical Materials · doi:10.1002/adom.201300368 · Cited by 188 · see citing works
Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials
Chen, S., Xiong, C., Liu, H., Wan, Q., Hou, J., He, Q., Badu-Tawiah, A. K., & Nie, Z. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2014.282 · Cited by 188 · see citing works
Graphene Oxide as a Quencher for Fluorescent Assay of Amino Acids, Peptides, and Proteins
Li, S., Aphale, A. N., Macwan, I., Patra, P., Gonzalez, W. G., Mikšovská, J., & Leblanc, R. M. (2012) · ACS Applied Materials & Interfaces · doi:10.1021/am302704a · Cited by 186 · see citing works
Wang, C., Ravi, S., Garapati, U. S., Das, M., Howell, M., Mallela, J. P., Alwarappan, S., Mohapatra, S. S., & Mohapatra, S. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20452a · Cited by 183 · see citing works
Nanomaterials for Reducing Amyloid Cytotoxicity
Zhang, M., Mao, X., Yu, Y., Wang, C.-X., Yang, Y., & Wang, C. (2013) · Advanced Materials · doi:10.1002/adma.201301210 · Cited by 183 · see citing works
A review of optical imaging and therapy using nanosized graphene and graphene oxide
Li, J., Tang, B., Yuan, B., Sun, L., & Wang, X.-G. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.08.066 · Cited by 179 · see citing works
Nanotransducers for Near‐Infrared Photoregulation in Biomedicine
Li, J., Duan, H., & Pu, K. (2019) · Advanced Materials · doi:10.1002/adma.201901607 · Cited by 171 · see citing works
Rational Design of Biomaterials to Potentiate Cancer Thermal Therapy
Zhu, Y., Li, Q., Wang, C., Hao, Y., Yang, N., Chen, M., Ji, J., Feng, L., & Liu, Z. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00822 · Cited by 163 · see citing works
Li, A., Li, X., Yu, X., Li, W., Zhao, R., An, X., Cui, D., Chen, X. S., & Li, W. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.10.024 · Cited by 163 · see citing works
Zong, L., Wu, H., Lin, H., & Chen, Y. (2018) · Nano Research · doi:10.1007/s12274-018-2002-3 · Cited by 163 · see citing works
Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease
Li, M., Howson, S. E., Dong, K., Gao, N., Ren, J., Scott, P., & Qu, X. (2014) · Journal of the American Chemical Society · doi:10.1021/ja502789e · Cited by 161 · see citing works
Self-citationPeng, H., Borg, R. E., Dow, L. P., Pruitt, B. L., & Chen, I. A. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1913234117 · Cited by 159 · see citing works
Palmal, S., Maity, A. R., Singh, B. K., Basu, S., Jana, N. R., & Jana, N. R. (2014) · Chemistry - A European Journal · doi:10.1002/chem.201400079 · Cited by 155 · see citing works
Advancements in nanotherapeutics for Alzheimer’s disease: current perspectives
Harilal, S., Jose, J., Parambi, D. G. T., Kumar, R., Mathew, G. E., Uddin, M. S., Kim, H., & Mathew, B. (2019) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13132 · Cited by 157 · see citing works
Pal, K., Asthana, N., Aljabali, A. A. A., Bhardwaj, S. K., Kralj, S., Penkova, A. V., Thomas, S., Zaheer, T., & de Souza, F. G. (2021) · Critical reviews in solid state and materials sciences/CRC critical reviews in solid state and materials sciences · doi:10.1080/10408436.2021.1935717 · Cited by 155 · see citing works
Demeritte, T., Nellore, B. P. V., Kanchanapally, R., Sinha, S. S., Pramanik, A., Chavva, S. R., & Ray, P. C. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b03619 · Cited by 154 · see citing works
The interplay between carbon nanomaterials and amyloid fibrils in bio-nanotechnology
Li, C., & Mezzenga, R. (2013) · Nanoscale · doi:10.1039/c3nr01644g · Cited by 153 · see citing works
Photoluminescent Graphene Nanoparticles for Cancer Phototherapy and Imaging
Nurunnabi, M., Khatun, Z., Reeck, G. R., Lee, D. Y., & Lee, Y.-K. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am504071z · Cited by 151 · see citing works
Debnath, K., Pradhan, N., Singh, B. K., Jana, N. R., & Jana, N. R. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b06510 · Cited by 149 · see citing works
Zhang, X., Liu, S., Song, X., Wang, H., Wang, J., Wang, Y., Huang, J., & Yu, J. (2019) · ACS Sensors · doi:10.1021/acssensors.9b00974 · Cited by 148 · see citing works
Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology
Hajipour, M. J., Santoso, M. R., Rezaee, F., Aghaverdi, H., Mahmoudi, M., & Perry, G. L. (2017) · Trends in biotechnology · doi:10.1016/j.tibtech.2017.06.002 · Cited by 143 · see citing works
Current Strategies for Modulating Aβ Aggregation with Multifunctional Agents
Du, Z., Li, M. C., Ren, J., & Qu, X. (2021) · Accounts of Chemical Research · doi:10.1021/acs.accounts.1c00055 · Cited by 139 · see citing works
Self-citationLi, J., Cai, S., Yu, E., Weng, B., Chen, X., Chen, J., Jia, H., & Xu, Y. (2018) · Applied Catalysis B: Environmental · doi:10.1016/j.apcatb.2018.04.011 · Cited by 136 · see citing works
Multifunctional Graphene Oxide‐based Triple Stimuli‐Responsive Nanotheranostics
Chen, Y., Xu, P., Shu, Z., Wu, M., Wang, L., Zhang, S., Zheng, Y., Chen, H., Wang, J., Li, Y., et al. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201400221 · Cited by 136 · see citing works
Dye-enhanced graphene oxide for photothermal therapy and photoacoustic imaging
Wang, Y., Fu, Y., Peng, Q., Guo, S., Liu, G., Li, J., Yang, H., & Chen, G. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20986e · Cited by 136 · see citing works
Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
Cai, P., Leow, W. R., Wang, X., Wu, Y., & Chen, X. (2017) · Advanced Materials · doi:10.1002/adma.201605529 · Cited by 135 · see citing works
Shao, W., Wei, Q., Wang, S., Li, F., Wu, J., Ren, J., Cao, F., Liao, H., Gao, J., Zhou, M., et al. (2020) · Materials Horizons · doi:10.1039/c9mh00660e · Cited by 134 · see citing works
Self-citationZhang, L., Li, Y., & Yu, J. C. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb21196g · Cited by 133 · see citing works
Sun, J., Wei, C., Liu, Y., Xie, W., Xu, M., Zhou, H., & Liu, J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.12.027 · Cited by 133 · see citing works
Kurapati, R., & Raichur, A. M. (2012) · Chemical Communications · doi:10.1039/c2cc38417e · Cited by 131 · see citing works
Ma, M., Gao, N., Li, X., Liu, Z., Pi, Z., Du, X., Ren, J., & Qu, X. (2020) · ACS Nano · doi:10.1021/acsnano.0c02733 · Cited by 131 · see citing works
Self-citation
- Authors
- Li, M., Yang, X., Ren, J., Qu, K., & Qu, X.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Qu, Xiaogang
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2012-03-07
- Volume
- 24
- Issue
- 13
- Pages
- 1722-1728
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2005626048
- Cited by
- 535
- References
- 49
- Citations by year
- 2026: 6 · 2025: 15 · 2024: 19 · 2023: 34 · 2022: 37 · 2021: 41 · 2020: 49 · 2019: 49 · 2018: 57 · 2017: 58 · 2016: 45 · 2015: 39 · 2014: 45 · 2013: 37 · 2012: 4
- FWCI
- 22.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Materials (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Physical Sciences › Engineering › Biomedical Engineering › Graphene and Nanomaterials Applications
- Keywords
- graphene oxide, near-infrared photothermal therapy, Alzheimer's disease, amyloid fibril formation, thioflavin S, NIR laser irradiation, amyloid plaques
- MeSH terms
- Alzheimer Disease, Amyloid, Animals, Cell Survival, Graphite, Humans, Hyperthermia, Induced, Oxides, Phototherapy, Thiazoles, PC12 Cells, Nanostructures, Mice, Rats, Benzothiazoles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review