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Cited by 328

The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.

A Review on Nano-Based Drug Delivery System for Cancer Chemoimmunotherapy

Open access
Mu, Weiwei, Chu, Qihui, Liu, Yongjun, Zhang, Na·2020·Nano-Micro Letters

Abstract

Although notable progress has been made on novel cancer treatments, the overall survival rate and therapeutic effects are still unsatisfactory for cancer patients. Chemoimmunotherapy, combining chemotherapeutics and immunotherapeutic drugs, has emerged as a promising approach for cancer treatment, with the advantages of cooperating two kinds of treatment mechanism, reducing the dosage of the drug and enhancing therapeutic effect. Moreover, nano-based drug delivery system (NDDS) was applied to encapsulate chemotherapeutic agents and exhibited outstanding properties such as targeted delivery, tumor microenvironment response and site-specific release. Several nanocarriers have been approved in clinical cancer chemotherapy and showed significant improvement in therapeutic efficiency compared with traditional formulations, such as liposomes (Doxil®, Lipusu®), nanoparticles (Abraxane®) and micelles (Genexol-PM®). The applications of NDDS to chemoimmunotherapy would be a powerful strategy for future cancer treatment, which could greatly enhance the therapeutic efficacy, reduce the side effects and optimize the clinical outcomes of cancer patients. Herein, the current approaches of cancer immunotherapy and chemoimmunotherapy were discussed, and recent advances of NDDS applied for chemoimmunotherapy were further reviewed.

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Metadata

Authors
Mu, W., Chu, Q., Liu, Y., & Zhang, N.
Venue
Nano-Micro Letters
Published
2020-07-05
Volume
12
Issue
1
Pages
142-142
ISSN
  • 2150-5551 (ISSN-L)
  • 2311-6706
OpenAlex
W3038795195
Cited by
328
References
158
FWCI
9.29
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: A Review on Nano-Based Drug Delivery System for Cancer Chemoimmunotherapy. https://app.cochat.ai/papers/10.1007/s40820-020-00482-6
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Mu, W., Chu, Q., Liu, Y., & Zhang, N. (2020). A Review on Nano-Based Drug Delivery System for Cancer Chemoimmunotherapy. Nano-Micro Letters. https://doi.org/10.1007/s40820-020-00482-6

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