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Cited by 28Body Composition Measurement TechniquesGestational Diabetes Research and ManagementObesity, Physical Activity, Diet

Body Composition During Pregnancy: Longitudinal Changes and Method Comparisons

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Bosaeus, Marja, Andersson-Hall, Ulrika, Andersson, Louise, Karlsson, Therese, Ellegård, Lars, Holmäng, Agneta·2020·Reproductive Sciences
DOI 10.1007/s43032-020-00141-6PMC PMC7272490
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Abstract

Abstract The Pregnancy Obesity Nutrition and Child Health study is a longitudinal study of reproductive health. Here we analyzed body composition of normal-weight and obese Swedish women by three methods during each trimester of pregnancy. Cross-sectional and longitudinal fat mass estimates using quantitative magnetic resonance (QMR) and bioelectrical impedance analysis (BIA) (Tanita MC-180MA-III) were compared with fat mass determined by air displacement plethysmography (ADP) in pregnancy weeks 8–12, 24–26, and 35–37 in normal-weight women (n = 122, BMI = 22.1 ± 1.6 kg/m2) and obese women (n = 29, BMI = 34.6 ± 3.6 kg/m2). ADP results were calculated from pregnancy-adjusted fat-free mass densities. Mean fat mass by QMR and ADP were similar in obese women, although with wide limits of agreement. In normal-weight women, QMR overestimated mean fat mass in all trimesters, with systematic overestimation at low fat mass values in trimesters 1 and 3. In obese women, fat mass by BIA was grossly underestimated and imprecise in all trimesters, especially at higher values in trimester 2. In normal-weight women, fat mass by BIA was moderately lower than by ADP in trimester 1, similar in trimester 2, and moderately higher in trimester 3. QMR and ADP assessed fat mass changes similarly in obese women, whereas BIA overestimated fat mass changes in normal-weight women. Mean fat mass and fat mass changes by QMR and pregnancy-adjusted ADP were similar in pregnant obese women. Mean fat mass by QMR and fat mass changes by BIA were higher than corresponding values determined by pregnancy-adjusted ADP in normal-weight women.

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  • Compared to prior longitudinal BIA studies in healthy pregnant cohorts, which were often limited by small single-center sample sizes or lacked rigorous post hoc complication screening, the multicenter design and strict exclusion criteria ensured that these curves reflected a highly reliable physiological baseline.

    “Compared to prior longitudinal BIA studies in healthy pregnant cohorts, which were often limited by small single-center sample sizes or lacked rigorous post hoc complication screening [25-27], our multicenter design and strict exclusion criteria ensured that these curves reflected a highly reliable physiological baseline.”

    From Trimester-Specific Bioelectrical Impedance Reference Curves in Physiological Pregnancy: Mapping Maternal Body Composition and Hydration Trajectories (2026) · cites this paper as [27]

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Authors
Bosaeus, M., Andersson-Hall, U., Andersson, L., Karlsson, T., Ellegård, L., & Holmäng, A.
Affiliations
  • University of Gothenburg (SE)
  • Sahlgrenska University Hospital (SE)
Corresponding author
Andersson-Hall, Ulrika
ORCID
Venue
Reproductive Sciences
Publisher
Springer Science and Business Media LLC
Published
2020-01-28
Volume
27
Issue
7
Pages
1477-1489
ISSN
  • 1933-7191 (ISSN-L)
  • 1933-7205
DOI
10.1007/s43032-020-00141-6
PMC
PMC7272490
OpenAlex
W3005115363
Cited by
28
References
35
Citations by year
2026: 4 · 2025: 6 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 7 · 2020: 3
FWCI
2.26
Type
journal article
Language
en
Open access
Licence
Locations
  • Reproductive Sciences (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
University of Gothenburg
Topics
  • Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
body composition, pregnancy, fat mass, fat-free mass, maternal obesity, quantitative MRI, bioelectrical impedance analysis, air displacement plethysmography, method comparison, trimester changes, normal-weight women
MeSH terms
Adipose Tissue, Adult, Body Composition, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Longitudinal Studies, Middle Aged, Nutritional Status, Obesity, Pregnancy, Sweden, Absorptiometry, Photon, Body Mass Index, Electric Impedance, Young Adult

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