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Strategies and engineering aspects on the scale-up of bioreactors for different bioprocesses
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Geometric parameters of the bioreactor-height, diameter, tube compression, and useful volume-exert a decisive influence on light exposure, gas transfer, and homogeneity of the medium.
“Additionally, the geometric parameters of the bioreactor—such as height, diameter, tube compression, and useful volume—exert a decisive influence on several critical aspects of the process, such as efficient light exposure, gas transfer (CO2 and O2), and homogeneity of the medium (de Mello et al., 2024).”
From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as de Mello et al., 2024
Citations
The citation lists haven’t been fetched yet
References 137 · Cited by 117
Research works printed but not linked: 4
- Yang Y, Sha M. A beginner’s guide to bioprocess modes-batch, fed-batch, and continuous fermentation. Eppendorf. 2019;408:1–16.
- Behl M, Thakar S, Ghai H, et al. Basic biotechniques for bioprocess and chapter 21 - fundamentals of fermentation technology. Academic Press; 2023. p. 1–2.
- Yu H, Tan Z. New correlations of volumetric liquid-phase mass transfer coefficients in gas-inducing agitated tank reactors. Int J Chem Reactor Eng. 2012;10:8–10. https://doi.org/10.1515/1542-6580.1. · DOI
- Elsayed EA, Othman NZ, El Enshasy HA. Bioprocess optimization of Xanthan production by Xanthomonas campestris using semi-defined medium in batch and fed-batch culture. Pharm Lett. 2016;8:288–96.
Metadata
- Authors
- de Mello, A. F. M., de Souza Vandenberghe, L. P., Herrmann, L. W., Letti, L. A. J., Burgos, W. J. M., Scapini, T., Manzoki, M. C., de Oliveira, P. Z., & Soccol, C. R.
- Affiliations
- Universidade Federal do Paraná (BR)
- ORCID
- Venue
- Systems Microbiology and Biomanufacturing
- Published
- 2023-10-10
- Volume
- 4
- Issue
- 2
- Pages
- 365-385
- ISSN
- 2662-7655 (ISSN-L)
- 2662-7663
- OpenAlex
- W4387503770
- Cited by
- 117
- References
- 137
- Citations by year
- 2026: 43 · 2025: 53 · 2024: 20 · 2023: 1
- FWCI
- 9.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Systems Microbiology and Biomanufacturing (publishedVersion)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES-PROEX)
- Topics
- Physical Sciences › Chemical Engineering › Fluid Flow and Transfer Processes › Fluid Dynamics and Mixing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Viral Infectious Diseases and Gene Expression in Insects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- bioreactor scale-up, scale-up strategies, geometric similarity, agitation, aeration, submerged fermentation, solid-state fermentation, photobioreactors, power consumption, process transfer, cell growth
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