The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The circadian blood pressure pattern in ambulatory normal subjects
Abstract
Ambulatory blood pressure (BP) monitoring using a portable noninvasive device capable of automatically measuring and recording BP every 7.5 minutes during a 24-hour study period was performed in 34 normal volunteers on 2 separate occasions, 2 to 8 weeks apart, to test the consistency of the whole-day blood pressure pattern. The average of all systolic BPs measured during the second study day was within 10 mm Hg of that measured during the first study day in 79% of the subjects, and the respective diastolic BP averages were within 5 mm Hg of each other in 65% of the subjects; 53% satisfied both of these criteria. The reproducibility of the circadian pattern of the BP was tested by dividing the 24-hour day into 12 consecutive 2-hour BP averages. When the corresponding 2-hour periods on the 2 study days were matched, there were strong correlations (r greater than 0.70) within most subjects for both the systolic and diastolic BP averages of the 2-hour periods (76% and 68% of subjects) and for the relative rank values of the periods (62% and 56%). Moreover, there were no significant differences between the averages (for all subjects together) on the 2 study days of the highest and lowest systolic and diastolic 2-hour BP values; similarly, the times at which these extreme values occurred on the 2 study days corresponded closely. Thus, in normal subjects there is a strong tendency for the circadian pattern and the actual levels of BP to be consistent between 24-hour study periods.
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“Almost all cardiovascular (CV) variables that have been assessed at different times of day and night in humans have been found to have a day/night pattern, including blood pressure (BP) (1-3), heart rate (HR) (3), circulating catecholamines (4), blood coagulation markers (5), and vascular endothelial function (6).”
From Role of the circadian system in cardiovascular disease (2018) · cites this paper as [1]
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Metadata
- Authors
- Weber, M. A., Drayer, J. I. M., Nakamura, D. K., & Wyle, F. A.
- Affiliations
- United States Department of Veterans Affairs (US)
- University of California, Irvine (US)
- ORCID
- Weber, Michael A.
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1984-07
- Volume
- 54
- Issue
- 1
- Pages
- 115-119
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2006629690
- Cited by
- 128
- References
- 12
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 6 · 2019: 1 · 2018: 1 · 2017: 2
- FWCI
- 4.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- circadian blood pressure rhythm, ambulatory blood pressure monitoring, reproducibility, normal subjects, 24-hour ambulatory blood pressure, systolic blood pressure, diastolic blood pressure, day-night blood pressure variation
- MeSH terms
- Adult, Blood Pressure, Circadian Rhythm, Diastole, Heart, Humans, Male, Middle Aged, Systole
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