Cited by 128Blood Pressure and Hypertension StudiesNon-Invasive Vital Sign MonitoringCardiovascular Health and Disease Prevention

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The circadian blood pressure pattern in ambulatory normal subjects

Weber, Michael A., Drayer, Jan I.M., Nakamura, Dina K., Wyle, Frederic A.·1984·The American Journal of Cardiology

DOI 10.1016/0002-9149(84)90314-x

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Abstract

Ambulatory blood pressure (BP) monitoring using a portable noninvasive device capable of automatically measuring and recording BP every 7.5 minutes during a 24-hour study period was performed in 34 normal volunteers on 2 separate occasions, 2 to 8 weeks apart, to test the consistency of the whole-day blood pressure pattern. The average of all systolic BPs measured during the second study day was within 10 mm Hg of that measured during the first study day in 79% of the subjects, and the respective diastolic BP averages were within 5 mm Hg of each other in 65% of the subjects; 53% satisfied both of these criteria. The reproducibility of the circadian pattern of the BP was tested by dividing the 24-hour day into 12 consecutive 2-hour BP averages. When the corresponding 2-hour periods on the 2 study days were matched, there were strong correlations (r greater than 0.70) within most subjects for both the systolic and diastolic BP averages of the 2-hour periods (76% and 68% of subjects) and for the relative rank values of the periods (62% and 56%). Moreover, there were no significant differences between the averages (for all subjects together) on the 2 study days of the highest and lowest systolic and diastolic 2-hour BP values; similarly, the times at which these extreme values occurred on the 2 study days corresponded closely. Thus, in normal subjects there is a strong tendency for the circadian pattern and the actual levels of BP to be consistent between 24-hour study periods.

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Authors: Weber, M. A., Drayer, J. I. M., Nakamura, D. K., & Wyle, F. A.
Affiliations: United States Department of Veterans Affairs (US)
University of California, Irvine (US)
ORCID: Weber, Michael A.
Venue: The American Journal of Cardiology
Publisher: Elsevier BV
Published: 1984-07
Volume: 54
Issue: 1
Pages: 115-119
ISSN: 0002-9149 (ISSN-L)
DOI: 10.1016/0002-9149(84)90314-x
OpenAlex: W2006629690
Cited by: 128
References: 12
Citations by year: 2026: 1 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 6 · 2019: 1 · 2018: 1 · 2017: 2
FWCI: 4.01
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The American Journal of Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Keywords: circadian blood pressure rhythm, ambulatory blood pressure monitoring, reproducibility, normal subjects, 24-hour ambulatory blood pressure, systolic blood pressure, diastolic blood pressure, day-night blood pressure variation
MeSH terms: Adult, Blood Pressure, Circadian Rhythm, Diastole, Heart, Humans, Male, Middle Aged, Systole

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The circadian blood pressure pattern in ambulatory normal subjects

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