CoChat
Sign Up
Cited by 210Cardiovascular Function and Risk FactorsBariatric Surgery and OutcomesCardiovascular Disease and Adiposity

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Effect of weight loss on cardiac chamber size, wall thickness and left ventricular function in morbid obesity

Alpert, Martin A., Terry, Boyd E., Kelly, Diana L.·1985·The American Journal of Cardiology
DOI 10.1016/0002-9149(85)90156-0
Open this paper in CoChat — free account

Abstract

To determine cardiac chamber size, wall thickness and left ventricular (LV) systolic function in morbidly obese patients, M-mode and cross-sectional echocardiography was performed in 62 patients whose body weight was greater than or equal to twice their ideal weight but who were free from underlying organic heart disease and systemic hypertension. The initial clinical protocol consisted of a medical history, physical examination, electrocardiogram at rest, chest x-ray and echocardiogram. Thereafter, each patient underwent gastric restriction. Thirty-four patients returned for follow-up echocardiography 4.3 +/- 0.3 months after substantial weight loss was achieved. For the whole group (n = 62) and LV internal dimension in diastole was enlarged in 24 (39%), the right ventricular internal dimension was enlarged in 20 (32%), the left atrial dimension was enlarged in 25 (40%) and the ventricular septal and LV posterior wall thickness was increased in 35 (56%). In the 34 patients who returned for follow-up, mean body weight decreased significantly, from 135 +/- 8 to 79 +/- 6 kg (73 +/- 4% of the amount over ideal body weight). In the subgroup with low preoperative LV fractional shortening (n = 13), mean LV fractional shortening increased from 22 +/- 2% to 31 +/- 2% (p less than 0.01). This was accompanied by a significant decrease in the mean LV internal dimension in diastole and mean blood pressure. The results indicate that cardiac chamber enlargement, LV hypertrophy and LV systolic dysfunction occur frequently in morbidly obese patients and that LV systolic dysfunction in such persons may improve following substantial weight loss.

Overview

Integrity signals

Registry

Crossref · 10.1016/0002-9149(85)90156-0

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 27 references

Research works printed but not linked: 1

  1. Woodward, 1978, Pathogenesis of myocardial dysfunction in extreme obesity, Circulation, 58, II

Cited by

Sorted by citations

Items 101–200 of 210

Related

See all

Metadata

Authors
Alpert, M. A., Terry, B. E., & Kelly, D. L.
Affiliations
University of Missouri (US)
Corresponding author
Alpert, Martin A.
ORCID
Alpert, Martin A.
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1985-03
Volume
55
Issue
6
Pages
783-786
ISSN
0002-9149 (ISSN-L)
DOI
10.1016/0002-9149(85)90156-0
OpenAlex
W2034351482
Cited by
210
References
27
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 7 · 2018: 5 · 2017: 3 · 2016: 10 · 2015: 7 · 2014: 9 · 2013: 11 · 2012: 5
FWCI
4.17
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords
morbid obesity, weight loss, left ventricular systolic function, left ventricular hypertrophy, cardiac chamber enlargement, left atrial enlargement, right ventricular dilatation, gastric restriction, blood pressure reduction
MeSH terms
Adult, Body Weight, Cardiac Volume, Echocardiography, Female, Follow-Up Studies, Heart, Heart Ventricles, Humans, Male, Myocardial Contraction, Myocardium, Obesity

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review