Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment
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Class Ic and Ia drugs cause use-dependent slowing of conduction, and class III drugs prolong refractoriness at His-Purkinje tissue more than in the ventricular myocardium.
“Class Ic and Ia drugs cause use-dependent slowing of conduction, and class III drugs prolong refractoriness at His-Purkinje tissue more than in the ventricular myocardium.54,55”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [55]
Class Ic and Ia drugs and class III drugs can both result in atypical BBB morphologies during SVT that mimics VT.
“They can both result in atypical BBB morphologies during SVT that mimics VT.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [55]
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- Authors
- Crijns, H. J., van Gelder, I. C., & Lie, K. I.
- Affiliations
- University Medical Center Groningen (NL)
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1988-12
- Volume
- 62
- Issue
- 17
- Pages
- 1303-1306
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W2033232925
- Cited by
- 120
- References
- 2
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2021: 7 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 3 · 2014: 2 · 2013: 3 · 2012: 4
- FWCI
- 2.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- supraventricular tachycardia, flecainide, wide complex tachycardia, QRS widening, class Ic antiarrhythmic drugs, bundle branch block
- MeSH terms
- Aged, Bundle-Branch Block, Electrocardiography, Female, Flecainide, Humans, Male, Middle Aged, Tachycardia, Tachycardia, Supraventricular
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