Cited by 25Blood Pressure and Hypertension StudiesCardiac Health and Mental HealthTreatment of Major Depression

Systemic hypertension associated with tricyclic antidepressant treatment in patients with panic disorder

Louie, Alan K., Louie, Eric K., Lannon, Richard A.·1992·The American Journal of Cardiology

Abstract

In a sample of 114 patients, 6 patients developed hypertension while taking tricyclic antidepressants. All these patients were diagnosed as having panic disorder, with or without major depression. Half of the 6 patients had a previous diagnosis of hypertension, which had been well controlled by antihypertensive drugs for years. A comparison group of patients with major depression, who had never had panic attacks, had no cases of hypertension induced by these antidepressants. These findings raise the possibility that patients who have panic disorder may experience cardiovascular disregulation that increases their risk for antidepressant-induced hypertension.

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Registry

Crossref · 10.1016/0002-9149(92)90766-r

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19 of 19 references verified0 citation errors · 0 not checkable

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Authors
Louie, A. K., Louie, E. K., & Lannon, R. A.
Affiliations
Loyola University Medical Center (US)
Corresponding author
Louie, Alan K.
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1992-11
Volume
70
Issue
15
Pages
1306-1309
ISSN
0002-9149 (ISSN-L)
OpenAlex
W2000502229
Cited by
25
References
19
Citations by year
2020: 1 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 1
FWCI
1.46
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5k11mh000582-02)
  • National Institute of Mental Health (MH-00582)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
tricyclic antidepressants, hypertension, panic disorder, cardiovascular dysregulation, major depressive disorder, adverse drug reactions
MeSH terms
Adult, Antidepressive Agents, Tricyclic, Female, Humans, Hypertension, Male, Panic Disorder

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