The general adaptation syndrome and the diseases of adaptation
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Selye's alarm reaction was not 'nonspecific' but had important physiologic functions as both a highly specific energy appeal reaction and a specific water retention reaction.
“Today we can say that Selye’s alarm reaction was not “nonspecific” but rather had important physiologic functions as both, a highly specific energy appeal reaction (as described earlier [9, 10]) as well as a specific water retention reaction.”
From Evolutionary medicine and chronic inflammatory state—known and new concepts in pathophysiology (2012) · cites this paper as [36]
Cites
A Syndrome produced by Diverse Nocuous Agents
Selye, H. (1936) · Nature · doi:10.1038/138032a0 · Cited by 3,967 · see citing works
Self-citationTHE GENERAL ADAPTATION SYNDROME AND THE DISEASES OF ADAPTATION1
Selye, H. (1946) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-6-2-117 · Cited by 2,296 · see citing works
Self-citationThymus and Adrenals in the Response of the Organism to Injuries and Intoxications
Selye, H. (1936) · PubMed Central · Cited by 384 · see citing works
Self-citationSelye, H. (1937) · Endocrinology · doi:10.1210/endo-21-2-169 · Cited by 382 · see citing works
Self-citationParticipation of Adrenal Cortex in Pathogenesis of Arthritis
Selye, H. (1949) · BMJ · doi:10.1136/bmj.2.4637.1129 · Cited by 175 · see citing works
Self-citationHORMONAL PRODUCTION OF ARTHRITIS
Selye, H. (1944) · JAMA · doi:10.1001/jama.1944.02850040001001 · Cited by 80 · see citing works
Self-citationSelye, H., & Fortier, C. (1949) · PubMed · Cited by 63 · see citing works
Self-citationSelye, H. (1951) · BMJ · doi:10.1136/bmj.1.4701.263 · Cited by 52 · see citing works
Self-citationRôle of the Hypophysis in the Pathogenesis of the Diseases of Adaptation.
Selye, H. (1944) · PubMed · Cited by 30 · see citing works
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Neurosteroids in the context of stress: implications for depressive disorders
Girdler, S. S., & Klatzkin, R. (2007) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2007.05.006 · Cited by 148 · see citing works
Evolutionary medicine and chronic inflammatory state—known and new concepts in pathophysiology
Straub, R. H. (2012) · Journal of Molecular Medicine · doi:10.1007/s00109-012-0861-8 · Cited by 105 · see citing works
- Authors
- Selye, H.
- Corresponding author
- Selye, Hans
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 1951-05
- Volume
- 10
- Issue
- 5
- Pages
- 549-555
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W2003374987
- Cited by
- 158
- References
- 9
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 24 · 2022: 3 · 2021: 9 · 2020: 6 · 2019: 3 · 2018: 6 · 2017: 5 · 2016: 7 · 2015: 10 · 2014: 1 · 2013: 4 · 2012: 3
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Medicinal Plants and Bioactive Compounds
- Keywords
- general adaptation syndrome, alarm response, endocrine system, hypertension, nephrosclerosis, rheumatic diseases, stress physiology
- MeSH terms
- General Adaptation Syndrome, Humans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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