The mechanism of hypoproteinemia in patients with regional enteritis and ulcerative colitis
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The half-life of albumin is shortened in some disease states, decreasing total albumin mass.
“The half‐life of albumin has been shown to shorten, decreasing total albumin mass.”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [76]
Turnover time of serum albumin has been found to be shortened in hypertension, acromegaly, nephrotic syndrome, and protein-losing enteropathy.
“This has been rarely measured, but turnover time has been found to be shortened in hypertension, acromegaly, nephrotic syndrome, and protein‐losing enteropathy.65, 74, 75, 76”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [76]
In the Western world, the severity of inflammatory effects of comorbidity, obesity, lifestyle, organ failure, and aging leads to a proportional decrease in serum albumin levels.
“In the Western world, the severity of the inflammatory effects of comorbidity, obesity, lifestyle, organ failure, and aging lead to a proportional decrease in serum albumin levels.23, 76, 101, 102, 103, 104, 105, 106”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [76]
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Hypoalbuminemia: Pathogenesis and Clinical Significance
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- Authors
- Steinfeld, J. L., Davidson, J. D., Gordon, R. S., & Greene, F. E.
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 1960-09
- Volume
- 29
- Issue
- 3
- Pages
- 405-415
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W2006469615
- Cited by
- 136
- References
- 36
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 2
- FWCI
- 15.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Keywords
- hypoproteinemia, Crohn's disease, ulcerative colitis, serum albumin, albumin degradation, intestinal protein loss, albumin synthesis, plasma volume, iodine-131 albumin, protein-bound iodine
- MeSH terms
- Blood Proteins, Colitis, Colitis, Ulcerative, Crohn Disease, Humans, Hypoproteinemia, Ileitis
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