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Cited by 146Antifungal resistance and susceptibilityFungal Infections and StudiesYeasts and Rust Fungi Studies

Pulmonary disease caused by Candida species

Masur, Henry, Rosen, P.Peter, Armstrong, Donald·1977·The American Journal of Medicine
DOI 10.1016/0002-9343(77)90546-0
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Abstract

Candida species are often found in sputum specimens. Their role as a possible cause of pulmonary disease is a frequent consideration, particularly in patients receiving immunosuppressive or long-standing antimicrobial therapy. At Memorial Hospital and New York Hospital, 30 patients with histologic evidence of Candida pulmonary infection were identified over a two year period. These infections reached the lungs by hematogenous spread in 10 patients and by aspiration in 16 patients. Most the patients had malignant neoplastic disease. The Candida pulmonary disease appeared to be significant clinical factor in only three cases. Experience from our institutions and from the literature indicates that Candida species rarely cause significant pulmonary disease. When such involvement is extensive, the patient is usually terminally ill from multiple other factors.

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Crossref · 10.1016/0002-9343(77)90546-0

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67 of 67 references verified0 citation errors · 0 not checkable

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  • Rarely, after aspiration of oropharyngeal material, primary pneumonia due to Candida may develop.

    “Rarely, after aspiration of oropharyngeal material, primary pneumonia due to Candida may develop [176, 181,182].”

    From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [182]

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Authors
Masur, H., Rosen, P. P., & Armstrong, D.
Corresponding author
Armstrong, Donald
ORCID
Masur, Henry
Venue
The American Journal of Medicine
Publisher
Elsevier BV
Published
1977-12
Volume
63
Issue
6
Pages
914-925
ISSN
0002-9343 (ISSN-L)
DOI
10.1016/0002-9343(77)90546-0
OpenAlex
W2077170095
Cited by
146
References
67
Citations by year
2024: 1 · 2023: 6 · 2022: 4 · 2021: 4 · 2020: 3 · 2019: 5 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 1
FWCI
0.77
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The American Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
Keywords
pulmonary candidiasis, hematogenous spread, aspiration, immunosuppression, cancer, sputum
MeSH terms
Biopsy, Candida, Candida albicans, Candidiasis, Humans, Leukemia, Lung, Lung Diseases, Fungal, Lymphoma, Sputum

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