Circulating prolactin levels during the menstrual cycle: Episodic release and diurnal variation
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Serum PRL levels are significantly greater in females than in males when a large group of samples is examined, although with marked overlap.
“Although a marked degree of overlap was found, serum PRL levels were significantly greater in females than in males when a large group of samples was examined (6).”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
Before treatment, serum PRL levels in the hypogonadal subjects were comparable to values found in premenopausal women.
“Before treatment, serum PRL levels in this group of hypogonadal subjects were comparable to the values found in premenopausal women (6).”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
A quantitatively greater nocturnal episodic PRL release occurs during midcycle than during other phases of the menstrual cycle.
“Moreover, a quantitatively greater nocturnal episodic PRL release has been seen during midcycle than during other phases of the cycle (6).”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
Meaningful assessment of the physiologic and pharmacologic events of PRL release cannot be established unless frequent sampling at shorter intervals over a period of at least several hours is obtained.
“In view of the recent demonstration of the episodic nature of PRL release (6, 10), meaningful assessment of the physiologic and pharmacologic events cannot be established unless frequent sampling at shorter intervals over a period of at least several hours is obtained.”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
The detailed characterization of this assay in the authors' laboratory has been reported recently.
“The detailed characterization of this assay in our laboratory has been reported recently (6).”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
The lack of an apparent elevation of PRL levels during the preovulatory phase of the cycle need not be inconsistent with the finding of an augmentation of PRL release by estrogen, because those studies were based on daily samples and subtle changes may have escaped a measurable effect.
“The lack of an apparent elevation of PRL levels during the preovulatory phase of the cycle (6, 12) need not be inconsistent with the present finding of an augmentation of PRL release by estrogen since these studies were based on daily samples and since subtle changes may have escaped a measurable effect.”
From Augmentation of prolactin secretion by estrogen in hypogonadal women (1974) · cites this paper as [6]
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References 25 · Cited by 157
- Authors
- Ehara, Y., Siler, T., Van den Berg, G., Sinha, Y. N., & Yen, S. S. C.
- Affiliations
- University of California San Diego (US)
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1973-12
- Volume
- 117
- Issue
- 7
- Pages
- 962-970
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W1529873354
- Cited by
- 157
- References
- 25
- Citations by year
- 2020: 1
- FWCI
- 9.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Keywords
- prolactin, menstrual cycle, diurnal variation, circadian rhythm, luteinizing hormone surge, estrogen, ovulation, luteal phase, follicular phase, neuroendocrine regulation, ovarian function
- MeSH terms
- Adult, Amphetamine, Binding, Competitive, Circadian Rhythm, Estrogens, Female, Follicle Stimulating Hormone, Humans, Luteinizing Hormone, Menstruation, Pregnancy, Progesterone, Prolactin, Radioimmunoassay, Sleep, Stimulation, Chemical, Time Factors, Postpartum Period
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