The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Sensitive substrates for human leukocyte and porcine pancreatic elastase: A study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The KM for MeOSuc-AAPV-pNA was found to be 0.152 mM compared to a previously published value of 0.14 mM [29].”
From Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase (2021) · cites this paper as [29]
Citations
Cites
Ellman, G. L. (1959) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(59)90090-6 · Cited by 26,824
The preparation and properties of two new chromogenic substrates of trypsin
Erlanger, B. F., Kokowsky, N., & Cohen, W. (1961) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(61)90145-x · Cited by 3,346
Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine
Grassetti, D. R., & Murray, J. F. (1967) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(67)90426-2 · Cited by 988
The synthesis and analytical use of a highly sensitive and convenient substrate of elastase
Bieth, J. G., Spiess, B., & Wermuth, C. G. (1974) · Biochemical Medicine · doi:10.1016/0006-2944(74)90134-3 · Cited by 732
Nakajima, K., Powers, J. C., Ashe, B. M., & Zimmerman, M. D. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50690-6 · Cited by 595
Self-citationNew Fluorogenic Substrates for α-Thrombin, Factor Xa, Kallikreins, and Urokinase1
Morita, T., Kato, H., Iwanaga, S., Takada, K., Kimura, T., & Sakakibara, S. (1977) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a131840 · Cited by 382
Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates
Zimmerman, M. D., Ashe, B. M., Yurewicz, E. C., & Patel, G. F. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90006-9 · Cited by 264
Self-citationPowers, J. C., Gupton, B. F., Harley, A. D., Nishino, N., & Whitley, R. J. (1977) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(77)90203-0 · Cited by 223
Self-citationA new fluorogenic substrate for chymotrypsin
Zimmerman, M., Yurewicz, E. C., & Patel, G. F. (1976) · Analytical Biochemistry · doi:10.1016/s0003-2697(76)80066-8 · Cited by 187
Self-citationMcDonald, J. K., & Ellis, S. (1975) · Life Sciences · doi:10.1016/0024-3205(75)90137-x · Cited by 165
Research works printed but not linked: 8
- Hance, 1975, Amer. Rev. Resp. Dis, 112, 656
- Zimmerman, 1977, 75, 750
- Yurewicz, 1975, 34, 234
- Powers, 1977, Vol. 46, 208
- Lehninger, 1957, Vol. 3, 886
- Palgar, 1972, Acta Biochim. Biophys. Acad. Sci. Hung, 7, 319
- Hirohara, 1974, 71, 1643
- Geneste, 1969, 64, 683
Cited by
Sorted by citations
Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases
Korkmaz, B., Horwitz, M. S., Jenne, D. E., & Gauthier, F. (2010) · Pharmacological Reviews · doi:10.1124/pr.110.002733 · Cited by 898
Replacement Therapy for Alpha1-Antitrypsin Deficiency Associated with Emphysema
Wewers, M. D., Casolaro, M. A., Sellers, S. E., Swayze, S. C., McPhaul, K. M., Wittes, J. T., & Crystal, R. G. (1987) · New England Journal of Medicine · doi:10.1056/nejm198704233161704 · Cited by 631
Matrix Metalloproteinase Expression and Production by Alveolar Macrophages in Emphysema
Finlay, G. A., O’Driscoll, L., RUSSELL, K. J., D'ARCY, E. M., Masterson, J., FitzGerald, M. X., & O'CONNOR, C. M. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.1.9612018 · Cited by 437
Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates
Barrett, A. J. (1980) · Biochemical Journal · doi:10.1042/bj1870909 · Cited by 404
Wu, Q., Martin, R. J., Rino, J. G., Breed, R., Torres, R. M., & Chu, H. W. (2006) · Microbes and Infection · doi:10.1016/j.micinf.2006.10.012 · Cited by 301
Metadata
- Authors
- Castillo, M. J., Nakajima, K., Zimmerman, M., & Powers, J. C.
- Affiliations
- Georgia Institute of Technology (US)
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Corresponding author
- Powers, James C.
- Venue
- Analytical Biochemistry
- Publisher
- Elsevier BV
- Published
- 1979-10
- Volume
- 99
- Issue
- 1
- Pages
- 53-64
- ISSN
- 0003-2697 (ISSN-L)
- OpenAlex
- W2059777229
- Cited by
- 268
- References
- 28
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 6 · 2016: 3 · 2015: 1 · 2014: 4 · 2013: 3 · 2012: 3
- FWCI
- 5.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Analytical Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Peptidase Inhibition and Analysis
- Keywords
- elastase, neutrophil elastase, porcine pancreatic elastase, fluorogenic substrates, chromogenic substrates, 4-methylcoumarin, Ellman's reagent, 4,4'-dithiodipyridine, enzyme kinetics, substrate sensitivity
- MeSH terms
- Amino Acid Sequence, Animals, Humans, Indicators and Reagents, Kinetics, Leukocytes, Oligopeptides, Pancreas, Pancreatic Elastase, Peptide Hydrolases, Serine, Spectrometry, Fluorescence, Substrate Specificity, Swine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
