Cited by 67Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors ResearchCancer-related gene regulation

Rat liver nuclear N-acetyltransferases: Separation of two enzymes with both histone and spermidine acetyltransferase activity

Libby, Paul R.·1980·Archives of Biochemistry and Biophysics

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Crossref · 10.1016/0003-9861(80)90190-3

Cites

23 of 23 references verified0 citation errors · 0 not checkable

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  • Spermidine is acetylated at N8 by an N-acetyltransferase in the nucleus and then exported to the cytosol, where it is deacetylated by a metal-dependent N8-acetylspermidine deacetylase (PDAC).

    “Spermidine is acetylated at the N8 position by an N-acetyltransferase in the cell nucleus7 and then exported to the cytosol, where it is deacetylated by a metal-dependent N8-acetylspermidine deacetylase, also known as polyamine deacetylase (PDAC)89.”

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Authors
Libby, P. R.
Affiliations
Roswell Park Comprehensive Cancer Center (US)
Corresponding author
Libby, Paul R.
Venue
Archives of Biochemistry and Biophysics
Publisher
Elsevier BV
Published
1980-08
Volume
203
Issue
1
Pages
384-389
ISSN
0003-9861 (ISSN-L)
OpenAlex
W1978504375
Cited by
67
References
23
Citations by year
2025: 1 · 2024: 1 · 2022: 1 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 1
FWCI
2.67
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Biochemistry and Biophysics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Histone Deacetylase Inhibitors Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer-related gene regulation
Keywords
histone acetyltransferase, N-acetyltransferase, histone H3 acetylation, enzyme purification, Michaelis constant, acetyl-CoA
MeSH terms
Acetylation, Acetyltransferases, Animals, Cell Nucleus, DNA, Female, Histones, Kinetics, Liver, Spermine, Substrate Specificity, Rats

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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