Membrane fluidizing effects of the general anesthetic methoxyflurane elicit an acclimation response in Tetrahymena
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Volatile anesthetics act on species across the evolutionary tree, not only on human patients.
“However, volatile anesthetics exert actions not only on human patients, but on species spanning the evolutionary tree of life [1–8] (Figure 1).”
From The Biology of General Anesthesia from Paramecium to Primate (2019) · cites this paper as [3]
Cites
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751 · see citing works
The Membrane Actions of Anesthetics and Tranquilizers
Seeman, P. M. (1972) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06931-5 · Cited by 2,253 · see citing works
Drug Tolerance in Biomembranes: A Spin Label Study of the Effects of Ethanol
Chin, J. H., & Goldstein, D. B. (1977) · Science · doi:10.1126/science.193186 · Cited by 516 · see citing works
Some Physical Mechanisms in Narcosis.
Mullins, L. J. (1954) · Chemical Reviews · doi:10.1021/cr60168a003 · Cited by 344 · see citing works
Hamburger, K. (1957) · Experimental Cell Research · doi:10.1016/0014-4827(57)90074-5 · Cited by 172 · see citing works
The effect of two inhalation anesthetics of the order of spin-labeled phospholipid vesicles
Trudell, J. R., Hubbell, W. L., & Cohen, E. N. (1973) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(73)90485-9 · Cited by 169 · see citing works
Martin, C. E., Hiramitsu, K., Kitajima, Y., et al. (1976) · Biochemistry · doi:10.1021/bi00669a004 · Cited by 168 · see citing works
Self-citationThe Proton Relaxation of Benzyl Alcohol in Erythrocyte Membranes
Metcalfe, J. C., Seeman, P. M., & Burgen, A. S. V. (1968) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)12585-6 · Cited by 150 · see citing works
Speth, V., & Wunderlich, F. T. (1973) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(73)90467-7 · Cited by 149 · see citing works
Cell Membranes: Biochemistry, Cell Biology and Pathology
Birbeck, M. S. C. (1976) · Journal of Clinical Pathology · doi:10.1136/jcp.29.4.366-b · Cited by 145 · see citing works
Fukushima, H., Martin, C. E., Hisaya, I., et al. (1976) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(76)90271-x · Cited by 138 · see citing works
Studies on Tetrahymena membranes:
Nozawa, Y., Iida, H., Fukushima, H., et al. (1974) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(74)90038-8 · Cited by 126 · see citing works
General anaesthetics can selectively perturb lipid bilayer membranes
Miller, K. W., & Pang, K.-Y. Y. (1976) · Nature · doi:10.1038/263253a0 · Cited by 124 · see citing works
Interaction of general anesthetics with phospholipid vesicles and biological membranes
Vanderkooi, J. M., Landesberg, R., Selick, H. E., et al. (1977) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(77)90366-2 · Cited by 116 · see citing works
General anesthetics expand cell membranes at surgical concentrations.
Seeman, P., & Roth, S. (1972) · Biochimica et Biophysica Acta · doi:10.1016/0005-2736(72)90019-3 · Cited by 105 · see citing works
Wunderlich, F. T., Speth, V., Batz, W., et al. (1973) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(73)90007-2 · Cited by 104 · see citing works
Kasai, R., Kitajima, Y., Martin, C. E., et al. (1976) · Biochemistry · doi:10.1021/bi00669a005 · Cited by 104 · see citing works
Self-citationCurran, M., & Seeman, P. M. (1977) · Science · doi:10.1126/science.887931 · Cited by 82 · see citing works
Effect of sterol replacement in vivo on the fatty acid composition of Tetrahymena.
Ferguson, K. A., Davis, F. M., Conner, R. L., et al. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)41031-4 · Cited by 63 · see citing works
Kitajima, Y., & Thompson, G. A. (1977) · The Journal of Cell Biology · doi:10.1083/jcb.72.3.744 · Cited by 43 · see citing works
Self-citationThe effect of temperature on the fatty acid composition of Tetrahymena pyriformis WH-14.
Conner, R. L., & Stewart, B. Y. (1976) · PubMed · Cited by 24 · see citing works
The Effect of Temperature on the Fatty Acid Composition of Tetrahymena pyriformis WH‐14
Conner, R. L., & Stewart, B. Y. (1976) · The Journal of Protozoology · doi:10.1111/j.1550-7408.1976.tb05269.x · Cited by 23 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The Biology of General Anesthesia from Paramecium to Primate
Kelz, M. B., & Mashour, G. A. (2019) · Current Biology · doi:10.1016/j.cub.2019.09.071 · Cited by 151 · see citing works
Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
Eger, E. I., Raines, D. E., Shafer, S. L., Hemmings, H. C., & Sonner, J. M. (2008) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e318182aedb · Cited by 119 · see citing works
A hypothesis on the origin and evolution of the response to inhaled anesthetics
Sonner, J. M. (2008) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e31817ee684 · Cited by 63 · see citing works
- Authors
- Nandini-Kishore, S. G., Kitajima, Y., & Thompson, G. A.
- Affiliations
- The University of Texas at Austin (US)
- ORCID
- Kitajima, Yasuo
- Venue
- Biochimica et Biophysica Acta (BBA) - Biomembranes
- Publisher
- Elsevier BV
- Published
- 1977-11
- Volume
- 471
- Issue
- 1
- Pages
- 157-161
- ISSN
- 0005-2736 (ISSN-L)
- OpenAlex
- W2072196656
- Cited by
- 36
- References
- 22
- Citations by year
- 2019: 1 · 2012: 1
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochimica et Biophysica Acta (BBA) - Biomembranes (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Health Sciences › Medicine › Physiology › Erythrocyte Function and Pathophysiology
- Keywords
- methoxyflurane, general anesthetics, membrane fluidity, Tetrahymena pyriformis, fatty acid desaturase, thermal acclimation
- MeSH terms
- Acclimatization, Animals, Cell Membrane, Fatty Acids, Methoxyflurane, Phospholipids, Temperature, Tetrahymena pyriformis, Fatty Acid Desaturases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review