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Cited by 14

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Structures and fatty acid compositions of neutral glycosphingolipids of human plasma

Kościelak, J., Maśliński, W., Zieleński, J., Zdebska, E., Brudzyński, T., Miller-Podraza, H., Cedergren, B.·1978·Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Abstract

Major neutral glycosphingolipids were isolated from human plasma and their structures and fatty acid compositions studied. The four neutral glycosphingolipids of plasma were characterized as Glc beta(1 leads to 1)ceramide, Gal beta(1 leads to 1)- ceramide, Gal beta(1 leads to 4) Glc beta (1 leads to 1)ceramide, Gal alpha(1 leads to 4) Gal beta(1 leads to 4) Glc beta(1 leads to 1)ceramide and GalNAc beta(1 leads to 3) Gal (1 leads to 4) Gal (1 leads to 4) Glc beta(1 leads to 1)-ceramide. The glycosphingolipids contained mostly short chain fatty acids of which most prominent was C16. Erythrocyte glucosylceramide and lactosylceramide exhibited similar fatty acid compositions as their plasma counterparts. Triglycosylceramide and globoside of erythrocytes contained almost exclusively long-chain fatty acids. In lactosylceramide obtained from "p" erythrocytes, an accumulation of long-chain fatty acids was found; this accumulation was not observed, however, in lactosylceramide isolated from "p" plasma. It was concluded that plasma and erythrocyte glycosphingolipids are synthesized at separate sites where short- and long-chain fatty acids, respectively, are available. Plasma and erythrocyte glucosylceramide, and probably a fraction of lactosylceramide, exchange between plasma and erythrocyte pools. The latter conclusion is discussed in the light of the relative roles of carbohydrate and lipid moieties of the glycosphingolipids in maintaining their association with erythrocyte membrane…

Overview

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Registry

Crossref · 10.1016/0005-2760(78)90158-3

Cites

22 of 22 references verified0 citation errors · 0 not checkable

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Citations

Cites

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Research works printed but not linked: 2

  1. Ando, 1976, Biochim. Biophys. Acta, 424, 18
  2. Marcus, 1976, 73, 3263

Cited by

Metadata

Authors
Kościelak, J., Maśliński, W., Zieleński, J., Zdebska, E., Brudzyński, T., Miller-Podraza, H., & Cedergren, B.
Venue
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
Publisher
Elsevier BV
Published
1978-09
Volume
530
Issue
3
Pages
385-393
ISSN
0005-2760
Cited by
14
References
22
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.