The fate of psilocin in the rat
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After intravenous [14C]-psilocin in the rat, there was rapid uptake of radioactivity in the brain, followed by substantial biliary elimination.
“After intravenous of [14C]-psilocin in the rat, there was rapid uptake of radioactivity in the brain, followed by substantial biliary elimination [113].”
From Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans. (2021) · cites this paper as [113]
The major eliminated metabolites of [14C]-psilocin in rat were the glucoronate and 4-hydroxyindoleacetic acid.
“Chromatographic analysis indicated that the major eliminated metabolites were the glucoronate and 4-hydroxyindoleacetic acid.”
From Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans. (2021) · cites this paper as [113]
Cited by
Sorted by citations
Psilocybin – Summary of knowledge and new perspectives
Tylš, F., Páleníček, T., & Horáček, J. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.12.006 · Cited by 276 · see citing works
Metabolism of psilocybin and psilocin: clinical and forensic toxicological relevance
Dinis-Oliveira, R. J. (2017) · Drug Metabolism Reviews · doi:10.1080/03602532.2016.1278228 · Cited by 224 · see citing works
Psilocybin in neuropsychiatry: a review of its pharmacology, safety, and efficacy
Dodd, S., Norman, T. R., Eyre, H. A., Stahl, S. M., Phillips, A., Carvalho, A. F., & Berk, M. (2023) · CNS Spectrums · doi:10.1017/s1092852922000888 · Cited by 73 · see citing works
Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans.
Cumming, P., Scheidegger, M., Dornbierer, D., Palner, M., Quednow, B. B., & Martin-Soelch, C. (2021) · Molecules · doi:10.3390/molecules26092451 · Cited by 43 · see citing works
Hopf, A., & Eckert, H. (1969) · Psychopharmacologia · doi:10.1007/bf02456045 · Cited by 17 · see citing works
- Authors
- Kalberer, F., Kreis, W., & Rutschmann, J.
- Affiliations
- Sandoz Group AG (Switzerland) (CH)
- Venue
- Biochemical Pharmacology
- Publisher
- Elsevier BV
- Published
- 1962-04
- Volume
- 11
- Issue
- 4-5
- Pages
- 261-269
- ISSN
- 0006-2952 (ISSN-L)
- OpenAlex
- W2092674780
- Cited by
- 73
- References
- 0
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 6 · 2023: 4 · 2022: 9 · 2021: 2 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 3
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochemical Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Keywords
- psilocin, 14C-labeled compounds, pharmacokinetics, absorption, tissue distribution, excretion, metabolism, rats
- MeSH terms
- Animals, Hallucinogens, Psilocybin, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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