The lipid compositionof human bile
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Microbial conversion of choline into TMA likely accounts for a significant portion of TMAO production in subjects regardless of diet.
“Given the abundance of the choline moiety in both bile31 and common dietary staples (e.g. eggs, meat/fish, and some fruits/vegetables), microbial conversion of choline into TMA likely accounts for a significant portion of TMAO production in subjects, regardless of diet.”
From Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential (2018) · cites this paper as [31]
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- Authors
- Phillips, G. B.
- Affiliations
- NewYork–Presbyterian Hospital (US)
- Corresponding author
- Phillips, Gerald B.
- Venue
- Biochimica et Biophysica Acta
- Publisher
- Elsevier BV
- Published
- 1960-07
- Volume
- 41
- Issue
- 2
- Pages
- 361-363
- ISSN
- 0006-3002 (ISSN-L)
- OpenAlex
- W2031479075
- Cited by
- 64
- References
- 1
- Citations by year
- 2021: 1 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 1
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochimica et Biophysica Acta (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Keywords
- bile lipid composition, bile formation, cholestasis, progressive familial intrahepatic cholestasis, drug-induced cholestasis, bile salt export pump, MDR3, biliary phospholipid secretion, drug-induced liver injury, hepatocytes
- MeSH terms
- Bile, Humans, Lipids
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