The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study
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Loss of glutamate receptors typifies the early synaptic stage of neurodegeneration.
“A loss of glutamate receptors is what typifies this early synaptic stage of neurodegeneration (Yasuda et al., 1995; Wakabayashi et al., 1999; Qu et al., 2021)”
From The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease (2022) · cites this paper as Yasuda et al., 1995
The Introduction reports that loss of the GluR2/3 receptor subunit in layer II entorhinal neurons occurs before those neurons are lost, relatively early in Alzheimer’s disease. The Discussion also reports reduced GluR1 and GluR2/3 subunits in the entorhinal cortex. These findings support an early receptor change in a specific disease and region, but not the broader claim that glutamate-receptor loss typifies an early synaptic stage of neurodegeneration generally. (LLM, conf=0.85)
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Cites
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Alternative excitotoxic hypotheses
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Research works printed but not linked: 18
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Synaptic dysfunction in Alzheimer's disease: Mechanisms and therapeutic strategies
Chen, Y., Fu, A. K. Y., & Ip, N. Y. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.11.006 · Cited by 258
Zhao, W.-Q., Santini, F., Breese, R., Ross, D., Zhang, X. D., Stone, D. J., Ferrer, M., Townsend, M., Wolfe, A. L., Seager, M. A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.057182 · Cited by 188
Mishizen-Eberz, A. J., Rissman, R. A., Carter, T. L., Ikonomovic, M. D., Wolfe, B. B., & Armstrong, D. M. (2004) · Neurobiology of Disease · doi:10.1016/j.nbd.2003.09.016 · Cited by 156
Self-citationJürgensen, S., Antonio, L. L., Mussi, G. E. A., Brito-Moreira, J., Bomfim, T. R., De Felice, F. G., Garrido-Sanabria, E. R., Cavalheiro, É. A., & Ferreira, S. T. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.177790 · Cited by 88
Guntupalli, S., Jang, S. E., Zhu, T., Huganir, R. L., Widagdo, J., & Anggono, V. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.774554 · Cited by 70
Kalirin loss results in cortical morphological alterations
Xie, Z., Cahill, M. E., & Penzes, P. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.09.006 · Cited by 56
The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
Qureshi, Y. H., Berman, D. E., Marsh, S. E., Klein, R. L., Patel, V. M., Simoes, S., Kannan, S., Petsko, G. A., Stevens, B., & Small, S. A. (2022) · Cell Reports · doi:10.1016/j.celrep.2021.110262 · Cited by 31
Metadata
- Authors
- Yasuda, R. P., Ikonomovic, M. D., Sheffield, R., Rubin, R. T., Wolfe, B. B., & Armstrong, D. M.
- Venue
- Brain Research
- Publisher
- Elsevier BV
- Published
- 1995-04
- Volume
- 678
- Issue
- 1-2
- Pages
- 161-167
- ISSN
- 0006-8993
- Cited by
- 71
- References
- 3
- Language
- en
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