Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology

Neuropathological stageing of Alzheimer-related changes.

Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123 · see citing works

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

Monyer, H., Sprengel, R., Schoepfer, R., Herb, A., Higuchi, M., Lomeli, H., Burnashev, N., Sakmann, B., & Seeburg, P. H. (1992) · Science · doi:10.1126/science.256.5060.1217 · Cited by 2,541 · see citing works

Alzheimer's disease: cell-specific pathology isolates the hippocampal formation.

Hyman, B. T., Van Hoesen, G. W., Damasio, A. R., & Barnes, C. L. (1984) · Science · doi:10.1126/science.6474172 · Cited by 2,268 · see citing works

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

Yankner, B. A., Duffy, L. K., & Kirschner, D. A. (1990) · Science · doi:10.1126/science.2218531 · Cited by 1,975 · see citing works

The physiology of excitatory amino acids in the vertebrate central nervous system

Mayer, M. L., & Westbrook, G. L. (1987) · Progress in Neurobiology · doi:10.1016/0301-0082(87)90011-6 · Cited by 1,705 · see citing works

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

Mattson, M. P., Cheng, B., Davis, D. G., Bryant, K., Lieberburg, I. M., & Rydel, R. E. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-02-00376.1992 · Cited by 1,627 · see citing works

Molecular diversity of the NMDA receptor channel

Kutsuwada, T., Kashiwabuchi, N., Mori, H., Sakimura, K., Kushiya, E., Araki, K., Meguro, H., Hisashi, M., Kumanishi, T., Arakawa, M., et al. (1992) · Nature · doi:10.1038/358036a0 · Cited by 1,346 · see citing works

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

Ishii, T., Moriyoshi, K., Sugihara, H., Sakurada, K., Kadotani, H., Yokoi, M., Akazawa, C., Shigemoto, R., Mizuno, N., & Masu, M. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53849-7 · Cited by 982 · see citing works

N-methyl-D-aspartic acid receptor structure and function

McBain, C. J., & Mayer, M. L. (1994) · Physiological Reviews · doi:10.1152/physrev.1994.74.3.723 · Cited by 976 · see citing works

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

Yankner, B. A., Dawes, L. R., Fisher, S., Villa-Komaroff, L., Oster-Granite, M. L., & Neve, R. L. (1989) · Science · doi:10.1126/science.2474201 · Cited by 907 · see citing works

Functional and Pharmacological Differences Between Recombinant N -Methyl- d -Aspartate Receptors

Vicini, S., Wang, J. F., Li, J. H., Zhu, W. J., Wang, Y. H., Luo, J. H., Wolfe, B. B., & Grayson, D. R. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.2.555 · Cited by 674 · see citing works

Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia: A quantitative study

Ball, M. J. (1977) · Acta Neuropathologica · doi:10.1007/bf00692056 · Cited by 639 · see citing works

β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

Koh, J., Yang, L. L., & Cotman, C. W. (1990) · Brain Research · doi:10.1016/0006-8993(90)91355-k · Cited by 617 · see citing works

The Human Hippocampus

Duvernoy, H. M., Cattin, F., & Risold, P. (2013) · Springer eBooks · doi:10.1007/978-3-642-33603-4 · Cited by 567 · see citing works

Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

Laube, B., Hirai, H., Sturgess, M., Betz, H., & Kuhse, J. (1997) · Neuron · doi:10.1016/s0896-6273(00)81249-0 · Cited by 467 · see citing works

The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B).

Luo, J.-H., Wang, Y.-H., Yasuda, R., Dunah, A., & Wolfe, B. (1997) · Molecular Pharmacology · doi:10.1124/mol.51.1.79 · Cited by 427 · see citing works

Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins

Kuryatov, A. (1994) · Neuron · doi:10.1016/0896-6273(94)90445-6 · Cited by 385 · see citing works

Ionotropic Glutamate Receptors and Expression of N-Methyl- d -Aspartate Receptor Subunits in Subregions of Human Hippocampus: Effects of Schizophrenia

Gao, X.-M., Sakai, K., Roberts, R. C., Conley, R. R., Dean, B., & Tamminga, C. A. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.7.1141 · Cited by 371 · see citing works

Dementia of the Alzheimer's Type: Changes in Hippocampal L‐[ 3 H]Glutamate Binding

Greenamyre, J. T., Penney, J. B., D’Amato, C. J., & Young, A. B. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb04127.x · Cited by 279 · see citing works

Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells.

Priestley, T., Laughton, P., Myers, J., Bourdellès, B. L., Kerby, J., & Whiting, P. J. (1995) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10541-5 · Cited by 262 · see citing works

Functional Neurobiology of Aging

(2001) · Elsevier eBooks · doi:10.1016/b978-0-12-351830-9.x5000-8 · Cited by 246 · see citing works

Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia

Testa, C. M., Friberg, I. K., Weiss, S. W., & Standaert, D. G. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980105)390:1 · Cited by 237 · see citing works

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

Hirai, H., Kirsch, J., Laube, B., Betz, H., & Kuhse, J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.6031 · Cited by 223 · see citing works

Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease

Geddes, J. W., Chang-Chui, H., Cooper, S. M., Lott, I. T., & Cotman, C. W. (1986) · Brain Research · doi:10.1016/0006-8993(86)90611-6 · Cited by 211 · see citing works

Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule.

Chazot, P., Coleman, S., Cik, M., & Stephenson, F. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)51098-5 · Cited by 205 · see citing works

Identification of Amino Acid Residues of the NR2A Subunit That Control Glutamate Potency in Recombinant NR1/NR2A NMDA Receptors

Anson, L. C., Chen, P. E., Wyllie, D. J. A., Colquhoun, D., & Schoepfer, R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-02-00581.1998 · Cited by 200 · see citing works

Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors—an autoradiographic study

Jansen, K. L. R., Faull, R. L. M., Dragunow, M., & Synek, B. J. L. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90246-z · Cited by 197 · see citing works

Characterization of NMDA Receptor Subunit‐Specific Antibodies: Distribution of NR2A and NR2B Receptor Subunits in Rat Brain and Ontogenic Profile in the Cerebellum

Wang, Y., Bosy, T. Z., Yasuda, R. P., Grayson, D. R., Vicini, S., Pizzorusso, T., & Wolfe, B. B. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65010176.x · Cited by 160 · see citing works

N-Methyl-d-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer’s disease

Sze, C., Bi, H., Kleinschmidt-DeMasters, B. K., Filley, C. M., & Martin, L. J. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(00)00467-6 · Cited by 146 · see citing works

β-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus

Wu, J., Anwyl, R., & Rowan, M. J. (1995) · Neuroreport · doi:10.1097/00001756-199511270-00031 · Cited by 128 · see citing works

The Ca2+ influx induced by β‐amyloid peptide 25–35 in cultured hippocampal neurons results from network excitation

Brorson, J. R., Bindokas, V. P., Iwama, T., Marcuccilli, C. J., Chisholm, J. C., & Miller, R. J. (1995) · Journal of Neurobiology · doi:10.1002/neu.480260305 · Cited by 124 · see citing works

Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons

McBain, C. J., & Dingledine, R. J. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.68.1.16 · Cited by 121 · see citing works

Biochemical Evidence for the Co-association of Three N-Methyl-d-aspartate (NMDA) R2 Subunits in Recombinant NMDA Receptors

Hawkins, L. M., Chazot, P. L., & Stephenson, F. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.38.27211 · Cited by 114 · see citing works

Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias.

Penney, J. B., Maragos, W. F., Greenamyre, J. T., Debowey, D. L., Hollingsworth, Z. R., & Young, A. B. (1990) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.53.4.314 · Cited by 98 · see citing works

The messenger RNAs for the N-methyl- d-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain

Rigby, M., Bourdellès, B. L., HEAVENS, R. P., Kelly, S., Smith, D. W., Butler, A., Hammans, R., Hills, R., Xuereb, J. H., Hill, R., et al. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00089-9 · Cited by 92 · see citing works

The Loss of GluR2(3) Immunoreactivity Precedes Neurofibrillary Tangle Formation in the Entorhinal Cortex and Hippocampus of Alzheimer Brains

Ikonomović, M. D., Mizukami, K., Davies, P., Hamilton, R. L., Sheffield, R., & Armstrong, D. M. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199709000-00007 · Cited by 82 · see citing works

Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease

Cowburn, R. F., Hardy, J., Roberts‎, P., & BRIGGS, R. S. J. (1988) · Brain Research · doi:10.1016/0006-8993(88)90048-0 · Cited by 82 · see citing works

Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study

Yasuda, R. P., Ikonomović, M. D., Sheffield, R., Rubín, R. T., Wolfe, B. B., & Armstrong, D. M. (1995) · Brain Research · doi:10.1016/0006-8993(95)00178-s · Cited by 80 · see citing works

N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease

Ułas, J., Brunner, L. C., Geddes, J. W., Choe, W. S., & Cotman, C. W. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90075-d · Cited by 74 · see citing works

Chapter 4 Excitotoxin-mediated neuron death in youth and old age

Olney, J. W. (1990) · Progress in brain research · doi:10.1016/s0079-6123(08)63165-9 · Cited by 60 · see citing works

Amyloid β-protein fragment 25–35 causes activation of cytoplasmic calcium in neurons

Joseph, R., & Han, E. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)80044-0 · Cited by 59 · see citing works

Biochemical analysis of GABAA receptor subunits α1, α5, β1, β2 in the hippocampus of patients with Alzheimer's disease neuropathology

Rissman, R. A., Mishizen-Eberz, A. J., Carter, T. L., Wolfe, B. B., Blas, A. L. D., Miralles, C. P., Ikonomović, M. D., & Armstrong, D. M. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00030-7 · Cited by 59 · see citing works

Is senile dementia of the Alzheimer type associated with hippocampal plasticity?

Represa, A., Duyckaerts, C. J., Tremblay, E. C., Hauw, J., & Ben‐Ari, Y. (1988) · Brain Research · doi:10.1016/0006-8993(88)90706-8 · Cited by 58 · see citing works

Distribution of Glutamate Receptor Subunit NMDAR1 in the Hippocampus of Normal Elderly and Patients with Alzheimer's Disease

Ikonomović, M. D., Mizukami, K., Warde, D., Sheffield, R., Hamilton, R. L., Wenthold, R. J., & Armstrong, D. M. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7196 · Cited by 57 · see citing works

Non-plaque dystrophic dendrites in Alzheimer hippocampus: a new pathological structure revealed by glutamate receptor immunocytochemistry.

Aronica, E., Dickson, D., Kress, Y., Morrison, J. H., & Zukin, R. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00260-1 · Cited by 56 · see citing works

Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain.

Ułas, J., & Cotman, C. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00023-7 · Cited by 54 · see citing works

AMPA‐selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease

Ikonomović, M. D., Sheffield, R., & Armstrong, D. M. (1995) · Hippocampus · doi:10.1002/hipo.450050509 · Cited by 48 · see citing works

Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease

Geddes, J. W., & Cotman, C. W. (1986) · Neuroscience Research · doi:10.1016/0168-0102(86)90062-3 · Cited by 46 · see citing works

Amyloid β-peptide(25-35) changes [Ca2+] in hippocampal neurons

Mogensen, H. S., Beatty, D. M., Morris, S. J., & Jørgensen, O. S. (1998) · Neuroreport · doi:10.1097/00001756-199805110-00057 · Cited by 46 · see citing works

Expression of the NMDA R1 receptor in selected human brain regions

Böckers, T. M., Zimmer, M., Müller, A., Bergmann, M., Brose, N., & Kreutz, M. R. (1994) · Neuroreport · doi:10.1097/00001756-199404000-00028 · Cited by 43 · see citing works

Effects of post-mortem delay on subunits of ionotropic glutamate receptors in human brain

Wang, Y., TesFaye, E., Yasuda, R. P., Mash, D. C., Armstrong, D. M., & Wolfe, B. B. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00111-x · Cited by 38 · see citing works

GABAA receptor β2 and β3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology

Mizukami, K., Grayson, D. R., Ikonomović, M. D., Sheffield, R., & Armstrong, D. M. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00347-1 · Cited by 37 · see citing works

Binding to the glycine site of the NMDA receptor complex in brains of patients with Alzheimer's disease

Bel, E. A. D., & Slater, P. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90340-y · Cited by 17 · see citing works

Glutamate Receptors in Aging and Alzheimer's Disease

Mishizen-Eberz, A. J., Ikonomović, M. D., & Armstrong, D. M. (2001) · Elsevier eBooks · doi:10.1016/b978-012351830-9/50022-6 · Cited by 15 · see citing works

Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Lacor, P. N., Buniel, M. C., Furlow, P. W., Sanz Clemente, A., Velasco, P. T., Wood, M., Viola, K. L., & Klein, W. L. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3501-06.2007 · Cited by 1,188 · see citing works

Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease

Guo, T., Zhang, D., Zeng, Y., Huang, T. Y., Xu, H., & Zhao, Y. (2020) · Molecular Neurodegeneration · doi:10.1186/s13024-020-00391-7 · Cited by 994 · see citing works

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

Bezprozvanny, I., & Mattson, M. P. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.06.005 · Cited by 938 · see citing works

Selective vulnerability in neurodegenerative diseases

Fu, H., Hardy, J., & Duff, K. E. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0221-2 · Cited by 585 · see citing works

The Role of NMDA Receptors in Alzheimer’s Disease

Liu, J., Chang, L., Song, Y., Li, H., & Wu, Y. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00043 · Cited by 535 · see citing works

N-Methyl-d-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease

Waxman, E. A., & Lynch, D. R. (2005) · The Neuroscientist · doi:10.1177/1073858404269012 · Cited by 372 · see citing works

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

Xu, Y., Yan, J., Zhou, P., Li, J., Gao, H., Xia, Y., & Wang, Q. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.02.002 · Cited by 303 · see citing works

Dysfunction of NMDA receptors in Alzheimer’s disease

Zhang, Y., Li, P., Feng, J., & Wu, M. (2016) · Neurological Sciences · doi:10.1007/s10072-016-2546-5 · Cited by 282 · see citing works

Amyloid-β as a Modulator of Synaptic Plasticity

Parihar, M. S., & Brewer, G. J. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-101020 · Cited by 249 · see citing works

Dietary n‐3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease

Calon, F., Lim, G. P., Morihara, T., Yang, F., Ubeda, O. J., Salem, N., Frautschy, S. A., & Cole, G. M. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04253.x · Cited by 244 · see citing works

Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer’s Disease and Parkinson’s Disease

Nakajima, A., & Ohizumi, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143380 · Cited by 239 · see citing works

d-serine levels in Alzheimer’s disease: implications for novel biomarker development

Madeira, C., Lourenco, M. V., Vargas-Lopes, C., Suemoto, C. K., Brandão, C. O., Reis, T., Leite, R. E. P., Laks, J., Jacob-Filho, W., Pasqualucci, C. A., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.52 · Cited by 233 · see citing works

Lipid Rafts: Linking Alzheimer′s Amyloid‐βProduction, Aggregation, and Toxicity at Neuronal Membranes

Rushworth, J. V., & Hooper, N. M. (2010) · International Journal of Alzheimer s Disease · doi:10.4061/2011/603052 · Cited by 218 · see citing works

Dysfunctional synapse in Alzheimer's disease – A focus on NMDA receptors

Mota, S. I., Ferreira, I. L., & Rego, A. C. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.08.013 · Cited by 206 · see citing works

Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

Dubal, D. B., Zhu, L., Sanchez, P. E., Worden, K., Broestl, L., Johnson, E. C. B., Ho, K., Yu, G.-Q., Kim, D., Bétourné, A., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.5791-12.2015 · Cited by 192 · see citing works

Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-β-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats

Singh, A. K., Kashyap, M. P., Tripathi, V., Singh, S., Garg, G., & Rizvi, S. I. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0129-3 · Cited by 195 · see citing works

Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

Meftah, S., & Gan, J. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1129036 · Cited by 197 · see citing works

Oxidative Stress Occurs Prior to Amyloid Aβ Plaque Formation and Tau Phosphorylation in Alzheimer’s Disease: Role of Glutathione and Metal Ions

Roy, R. G., Mandal, P. K., & Maroon, J. C. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00486 · Cited by 194 · see citing works

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease

Rissman, R. A., & Mobley, W. C. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07237.x · Cited by 172 · see citing works

Decreased levels of PSD95 and two associated proteins and increased levels of BCl 2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: Insights into their potential roles for loss of synapses and memory, accumulation of Aβ, and neurodegeneration in a prodromal stage of Alzheimer's disease

Rukhsana Sultana, A., Banks, W. A., & Butterfield, D. A. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22227 · Cited by 171 · see citing works

Propargylamine-derived multitarget-directed ligands: fighting Alzheimer’s disease with monoamine oxidase inhibitors

Bolea, I., Gella, A., & Unzeta, M. (2012) · Journal of Neural Transmission · doi:10.1007/s00702-012-0948-y · Cited by 158 · see citing works

New targets for pharmacological intervention in the glutamatergic synapse

Gardoni, F., & Luca, M. D. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.06.022 · Cited by 153 · see citing works

Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies

Tejeda, G., & Díaz-Guerra, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18020268 · Cited by 126 · see citing works

Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain

Revilla, S., Sunol, C. E., García‐Mesa, Y., Giménez‐Llort, L., Sanfeliu, C., & Cristòfol, R. M. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.01.037 · Cited by 127 · see citing works

On the Hypes and Falls in Neuroprotection: Targeting the NMDA Receptor

Villmann, C., & Becker, C. (2007) · The Neuroscientist · doi:10.1177/1073858406296259 · Cited by 119 · see citing works

Susceptibility to calcium dysregulation during brain aging

Kumar, A. (2009) · Frontiers in Aging Neuroscience · doi:10.3389/neuro.24.002.2009 · Cited by 115 · see citing works

c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo

Sclip, A., Tozzi, A., Abaza, A., Cardinetti, D., Colombo, I., Calabresi, P., Salmona, M., Welker, E., & Borsello, T. (2014) · Cell Death and Disease · doi:10.1038/cddis.2013.559 · Cited by 103 · see citing works

Evidence of Aβ‐ and transgene‐dependent defects in ERK‐CREB signaling in Alzheimer’s models

Ma, Q., Harris‐White, M. E., Ubeda, O. J., Simmons, M., Beech, W. K., Lim, G. P., Teter, B., Frautschy, S. A., & Cole, G. M. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04869.x · Cited by 110 · see citing works

Cholinergic and glutamatergic alterations beginning at the early stages of Alzheimer disease: participation of the phospholipase A2 enzyme

Schaeffer, E. L., & Gattaz, W. F. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1092-0 · Cited by 98 · see citing works

The N-methyl-d-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats

Burgdorf, J. S., Zhang, X.-L., Weiss, C., Matthews, E. A., Disterhoft, J. F., Stanton, P. K., & Moskal, J. R. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.04.012 · Cited by 94 · see citing works

Simvastatin Prevents Dopaminergic Neurodegeneration in Experimental Parkinsonian Models: The Association with Anti-Inflammatory Responses

Yan, J., Xu, Y., Zhu, C., Zhang, L., Wu, A., Yang, Y., Xiong, Z., Deng, C., Huang, X., Yenari, M. A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020945 · Cited by 94 · see citing works

Central role for NMDA receptors in redox mediated impairment of synaptic function during aging and Alzheimer’s disease

Foster, T. C., Kyritsopoulos, C., & Kumar, A. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.05.012 · Cited by 92 · see citing works

Susceptibility of hippocampal neurons to Aβ peptide toxicity is associated with perturbation of Ca2+ homeostasis

Resende, R., Pereira, C., Agostinho, P. M., Vieira, A. P., Malva, J. O., & Oliveira, C. R. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.071 · Cited by 92 · see citing works

Pathogenesis of Abeta Oligomers in Synaptic Failure

Sivanesan, S., Tan, A., & Rajadas, J. (2013) · Current Alzheimer Research · doi:10.2174/1567205011310030011 · Cited by 84 · see citing works

NMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease

Huang, Y.-J., Lin, C., Lane, H., & Tsaid, G. E. (2012) · Current Neuropharmacology · doi:10.2174/157015912803217288 · Cited by 85 · see citing works

Excitotoxicity and new antiglutamatergic strategies in Parkinson's disease and Alzheimer's disease

Koutsilieri, E., & Riederer, P. F. (2007) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(08)70025-7 · Cited by 84 · see citing works

Glutamate Metabolizing Enzymes in Prefrontal Cortex of Alzheimer’s Disease Patients

Burbaeva, G. S., Бокша, И. С., Терешкина, Е. Б., Savushkina, O. K., Starodubtseva, L. I., & Turishcheva, M. S. (2005) · Neurochemical Research · doi:10.1007/s11064-005-8654-x · Cited by 79 · see citing works

The dentate gyrus in Alzheimer's disease

Ohm, T. G. (2007) · Progress in brain research · doi:10.1016/s0079-6123(07)63039-8 · Cited by 78 · see citing works

High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: The association with the up-regulation of NMDA receptor binding in the rat brain

Wang, Q., Zengin, A., Deng, C., Li, Y., Newell, K. A., Yang, G., Lü, Y., Wilder-Smith, E. P., Zhao, H., & Huang, X. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.11.016 · Cited by 76 · see citing works

Serum d-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker

Piubelli, L., Pollegioni, L., Rabattoni, V., Mauri, M. F., Cariddi, L. P., Versino, M., & Sacchi, S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01202-3 · Cited by 74 · see citing works

Differentially disrupted functional connectivity of the subregions of the inferior parietal lobule in Alzheimer’s disease

Wang, Z., Xia, M., Dai, Z., Liang, X., Song, H., He, Y., & Li, K. (2015) · Brain Structure and Function · doi:10.1007/s00429-013-0681-9 · Cited by 73 · see citing works

Postsynaptic density–membrane associated guanylate kinase proteins (PSD–MAGUKs) and their role in CNS disorders

Gardoni, F., Marcello, E. E., & Luca, M. D. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.068 · Cited by 71 · see citing works

Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease

Olajide, O. J., Suvanto, M. E., & Chapman, C. A. (2021) · Biology Open · doi:10.1242/bio.056796 · Cited by 71 · see citing works

Retinoic acid normalizes nuclear receptor mediated hypo-expression of proteins involved in β-amyloid deposits in the cerebral cortex of vitamin A deprived rats

Husson, M., Enderlin, V., Delacourte, A., Ghenimi, N., Alfos, S., Pallet, V., & Higueret, P. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.01.008 · Cited by 67 · see citing works

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Tanqueiro, S. R., Ramalho, R. M., Rodrigues, T. M., Lopes, L. V., Sebastião, A. M., & Diógenes, M. J. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00237 · Cited by 67 · see citing works

Post-translational modification of NMDA receptor GluN2B subunit and its roles in chronic pain and memory

Qiu, S., Li, X., & Zhuo, M. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.06.003 · Cited by 65 · see citing works

Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies

Nakajima, A., Ohizumi, Y., & Yamada, K. (2014) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2014.12.2.75 · Cited by 64 · see citing works

Cellular calcium signaling in the aging brain

Remya, C., Kumar, M., Kesavan, L., Jacob, R. S., Gunasekaran, S., Lakshmi, S., Sadasivan, C., & Omkumar, R. V. (2017) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2017.11.008 · Cited by 62 · see citing works

Treatment Guidelines for Alzheimer's Disease

Geldmacher, D. (2007) · The Primary Care Companion to The Journal of Clinical Psychiatry · doi:10.4088/pcc.v09n0205 · Cited by 57 · see citing works

Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus

Mayordomo‐Cava, J., Yajeya, J., Navarro‐López, J. D., & Jiménez‐Díaz, L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0134385 · Cited by 55 · see citing works

Toxicity of β-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-d-aspartate receptor subunits

Domingues, A. M. D. J., Almeida, S., DACRUZESILVA, E., Oliveira, C. R., & Rego, A. C. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.03.001 · Cited by 58 · see citing works

Early Intervention with an Estrogen Receptor β-Selective Phytoestrogenic Formulation Prolongs Survival, Improves Spatial Recognition Memory, and Slows Progression of Amyloid Pathology in a Female Mouse Model of Alzheimer's Disease

Zhao, L., Mao, Z., Chen, S., Schneider, L. S. S., & Brinton, R. D. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-122341 · Cited by 57 · see citing works

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder

Davies, N. W. S., Guillemin, G. J., & Brew, B. J. (2010) · International Journal of Tryptophan Research · doi:10.4137/ijtr.s4321 · Cited by 57 · see citing works

Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease

Ortiz-Sanz, C., Balantzategi, U., Quintela‐López, T., Ruiz, A., Luchena, C., Zuazo-Ibarra, J., Capetillo‐Zarate, E., Matute, C., Zugaza, J. L., & Alberdi, E. M. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04687-y · Cited by 55 · see citing works

Potential Future Neuroprotective Therapies for Neurodegenerative Disorders and Stroke

Tarawneh, R. M., & Galvin, J. E. (2010) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2009.12.003 · Cited by 53 · see citing works

Effects of maternally exposed coloring food additives on receptor expressions related to learning and memory in rats

Ceyhan, B. M., Gültekin, F., Doğuç, D. K., & Kulaç, E. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.02.016 · Cited by 51 · see citing works

Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators

Yao, L., & Zhou, Q. (2017) · Neural Plasticity · doi:10.1155/2017/2875904 · Cited by 48 · see citing works

Multipotent, Permeable Drug ASS234 Inhibits Aβ Aggregation, Possesses Antioxidant Properties and Protects from Aβ-induced Apoptosis In Vitro

Bolea, I., Gella, A., Monjas, L., Pérez, C., Rodrı́guez-Franco, M. I., Marco‐Contelles, J., Samadi, A., & Unzeta, M. (2013) · Current Alzheimer Research · doi:10.2174/15672050113109990151 · Cited by 45 · see citing works

The Role of Reelin Signaling in Alzheimer’s Disease

Yu, N., Tan, M., Yu, J., Xie, A., & Tan, L. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9459-9 · Cited by 44 · see citing works

Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP).

wu, S. O. S.-Z., Basile, A., & Barger, S. (2007) · Current Alzheimer Research · doi:10.2174/156720507781077241 · Cited by 46 · see citing works

Insoluble Aβ overexpression in an App knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, affecting anxiety-related behaviours

Pervolaraki, E., Hall, S. P., Foresteire, D., Saito, T., Saido, T. C., Whittington, M. A., Lever, C., & Dachtler, J. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.040550 · Cited by 42 · see citing works

Simvastatin prevents neuroinflammation by inhibiting N‐methyl‐D‐aspartic acid receptor 1 in 6‐hydroxydopamine‐treated PC12 cells

Yan, J., Sun, J., Huang, L., Fu, Q., & Du, G. (2014) · Journal of Neuroscience Research · doi:10.1002/jnr.23329 · Cited by 41 · see citing works

Trafficking and Targeting of NMDA Receptors

Petralia, R. S., Wenthold, R. J., & Al‐Hallaq, R. A. (2008) · Frontiers in neuroscience · doi:10.1201/9781420044157.ch8 · Cited by 41 · see citing works

Targeting N-Methyl-d-Aspartate Receptors in Neurodegenerative Diseases

Carles, A., Freyssin, A., Perin-Dureau, F., Rubinstenn, G., & Maurice, T. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073733 · Cited by 42 · see citing works

3-Nitropropionic acid toxicity in hippocampus: Protection throughN-methyl-D-aspartate receptor antagonism

Karanian, D. A., Baude, A. S., Brown, Q. B., Parsons, C. G., & Bahr, B. A. (2006) · Hippocampus · doi:10.1002/hipo.20214 · Cited by 39 · see citing works

The Functional and Molecular Properties, Physiological Functions, and Pathophysiological Roles of GluN2A in the Central Nervous System

Sun, Y., Cheng, X., Zhang, L., Hu, J. H., chen, Y., Zhan, L., & Gao, Z. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9715-7 · Cited by 38 · see citing works

Advances on the Understanding of the Origins of Synaptic Pathology in AD

Lacor, P. N. (2007) · Current Genomics · doi:10.2174/138920207783769530 · Cited by 38 · see citing works

Polymodal Regulation of NMDA Receptor-Channels

Kloda, A., Martinac, B., & Adams, D. J. (2007) · Channels · doi:10.4161/chan.5044 · Cited by 38 · see citing works

Genetic findings in sport-related concussions: potential for individualized medicine?

McDevitt, J. K., & Krynetskiy, E. Y. (2017) · Concussion · doi:10.2217/cnc-2016-0020 · Cited by 37 · see citing works

NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

Müller, M., Jacobi, E., Sakimura, K., Malinow, R., & von Engelhardt, J. (2018) · Acta Neuropathologica Communications · doi:10.1186/s40478-018-0611-4 · Cited by 38 · see citing works

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus — Linking NMDA receptors and the reelin pathway

Mota, S. I., Ferreira, I. L., Valero, J., Ferreiro, E. B., Carvalho, A. L., Oliveira, C. R., & Rego, A. C. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.07.023 · Cited by 36 · see citing works

NR2B-Containing NMDA Receptors Expression and Their Relationship to Apoptosis in Hippocampus of Alzheimer’s Disease-Like Rats

Liu, Z., Lv, C., Zhao, W., Song, Y., Pei, D., & Xu, T. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0726-0 · Cited by 36 · see citing works

Neuronal degeneration, synaptic defects, and behavioral abnormalities in tau45-230 transgenic mice

Lang, A. E., Riherd Methner, D. N., & Ferreira, A. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.06.017 · Cited by 35 · see citing works

Pathological Reorganization of NMDA Receptors Subunits and Postsynaptic Protein PSD-95 Distribution in Alzheimer’s Disease

Leuba, G., Vernay, A., Kraftsik, R., Tardif, É., Riederer, B. M., & Savioz, A. (2014) · Current Alzheimer Research · doi:10.2174/15672050113106660170 · Cited by 33 · see citing works

α-Synuclein-induced internalization of NMDA receptors in hippocampal neurons is associated with reduced inward current and Ca2+ influx upon NMDA stimulation

Chen, Y., Yang, W., Li, X., Li, X., Yang, H., Xu, Z., & Yu, S. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.05.035 · Cited by 34 · see citing works

N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APPSw,Ind Mice

Franco, R., Aguinaga, D., Reyes‐Resina, I., Canela, E. I., Lillo, J., Tarutani, A., Hasegawa, M., del Ser‐Badia, A., del Rı́o, J. A., Kreutz, M. R., et al. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00273 · Cited by 32 · see citing works

Plasticity of Glutamate and GABAA Receptors in the Hippocampus of Patients with Alzheimer's Disease

Armstrong, D. M., Sheffield, R., Mishizen-Eberz, A. J., Carter, T. L., Rissman, R. A., Mizukami, K., & Ikonomović, M. D. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1025063811290 · Cited by 32 · see citing works

Auditory Memory Decay as Reflected by a New Mismatch Negativity Score Is Associated with Episodic Memory in Older Adults at Risk of Dementia

Laptinskaya, D., Thurm, F., Küster, O. C., Fissler, P., Schlee, W., Kolassa, S., von Arnim, C. A. F., & Kolassa, I.-T. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00005 · Cited by 31 · see citing works

Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients

Escamilla, S., Badillos-Rodríguez, R., Comella, J. X., Solé, M., Pérez‐Otaño, I., Sanchez-Mut, J. V., Sáez‐Valero, J., & Cuchillo‐Ibáñez, I. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.14125 · Cited by 31 · see citing works

Adult‐Onset Hypothyroidism Induces the Amyloidogenic Pathway of Amyloid Precursor Protein Processing in the Rat Hippocampus

Ghenimi, N., Alfos, S., Redonnet, A., Higueret, P., Pallet, V., & Enderlin, V. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.02002.x · Cited by 31 · see citing works

Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors

Pietro, O. D., Alencar, N., Esteban, G., Viayna, E., Szałaj, N., Vázquez, J., Juárez‐Jiménez, J., Sola, I., Pérez, B., Solé, M., et al. (2016) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2016.06.045 · Cited by 30 · see citing works

Design, synthesis, and biological evaluation of novel N-Benzyl piperidine derivatives as potent HDAC/AChE inhibitors for Alzheimer’s disease

Qin, P., Ran, Y., Xie, F., Liu, Y., Wei, C., Luan, X., & Wu, J. (2023) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2023.117178 · Cited by 30 · see citing works

Unraveling the Neuroprotective Effect of Tinospora cordifolia in a Parkinsonian Mouse Model through the Proteomics Approach

Birla, H., Keswani, C., Singh, S. S., Zahra, W., Dilnashin, H., Rathore, A. S., Singh, R., Rajput, M., Keshri, P., & Singh, S. P. (2021) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.1c00481 · Cited by 28 · see citing works

Modulation of hippocampal calcium signalling and plasticity by serine/threonine protein phosphatases

Koss, D. J., Hindley, K. P., Riedel, G., & Platt, B. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04579.x · Cited by 28 · see citing works

Alterations of some membranetransportproteins in Alzheimer's disease: role of amyloid β-peptide

Rukhsana Sultana, A., & Butterfield, D. A. (2007) · Molecular BioSystems · doi:10.1039/b715278g · Cited by 28 · see citing works

Enhancement of Morphological Plasticity in Hippocampal Neurons by a Physically Modified Saline via Phosphatidylinositol-3 Kinase

Roy, A., Modi, K. K., Khasnavis, S., Ghosh, S., Watson, R. L., & Pahan, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101883 · Cited by 27 · see citing works

Differential Regulation of N-Methyl-D-Aspartate Receptor Subunits is An Early Event in the Actions of Soluble Amyloid-β1-40 Oligomers on Hippocampal Neurons

Chang, L., Zhang, Y., Liu, J., Song, Y., Lv, A., Li, Y., Zhou, W., Yan, Z., Almeida, O. F. X., & Wu, Y. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150942 · Cited by 27 · see citing works

Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease

Haseena, P. A., Basavaraju, N., Chandran, M., Jaleel, A., Bennett, D. A., & Kommaddi, R. P. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01558-w · Cited by 25 · see citing works

Transcriptional Regulation of NMDA Receptor Expression

Bai, G., & Hoffman, P. W. (2008) · Frontiers in neuroscience · doi:10.1201/9781420044157.ch5 · Cited by 25 · see citing works

Beta-amyloid oligomers induce early loss of presynaptic proteins in primary neurons by caspase-dependent and proteasome-dependent mechanisms

Jang, B.-G., In, S., Choi, B., & Kim, M.-J. (2014) · Neuroreport · doi:10.1097/wnr.0000000000000260 · Cited by 24 · see citing works

Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein

Rajão‐Saraiva, J., Dunot, J., Ribera, A., Temido‐Ferreira, M., Coelho, J. E., König, S., Moréno, S., Enguita, F. J., Willem, M., Kins, S., et al. (2023) · Aging Cell · doi:10.1111/acel.13778 · Cited by 23 · see citing works

Cinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement

Modi, K. K., Rangasamy, S. B., Dasarathi, S., Roy, A., & Pahan, K. (2016) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-016-9693-6 · Cited by 22 · see citing works

Sustained metabolic inhibition induces an increase in the content and phosphorylation of the NR2B subunit of N-methyl-d-aspartate receptors and a decrease in glutamate transport in the rat hippocampus in vivo

Camacho‐Morales, A., Montiel, T., & Massieu, L. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.12.069 · Cited by 21 · see citing works

NMDARs in Alzheimer’s Disease: Between Synaptic and Extrasynaptic Membranes

Escamilla, S., Sáez‐Valero, J., & Cuchillo‐Ibáñez, I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251810220 · Cited by 21 · see citing works

NMDA receptor/amyloid precursor protein interactions: A comparison between wild-type and amyloid precursor protein mutations associated with familial Alzheimer's disease

Innocent, N., Cousins, S. L., & Stephenson, F. A. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.03.029 · Cited by 19 · see citing works

Estradiol and lithium chloride specifically alter NMDA receptor subunit NR1 mRNA and excitotoxicity in primary cultures

Valdés, J. J., & Weeks, O. I. (2009) · Brain Research · doi:10.1016/j.brainres.2009.02.066 · Cited by 19 · see citing works

Neuroprotective effect of lovastatin by inhibiting NMDA receptor1 in 6-hydroxydopamine treated PC12 cells.

Yan, J., Ma, Y., Sun, J., Bai, S.-F., & Huang, L. (2014) · PubMed Central · Cited by 19 · see citing works

Acute and Chronic Sleep Deprivation-Related Changes in N-methyl-D-aspartate Receptor—Nitric Oxide Signalling in the Rat Cerebral Cortex with Reference to Aging and Brain Lateralization

Krištofiková, Z., Šírová, J., Klaschka, J., & Ovsepian, S. V. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133273 · Cited by 18 · see citing works

A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer’s disease

Catania, M., Colombo, L., Sorrentino, S., Cagnotto, A., Lucchetti, J., Barbagallo, M., Vannetiello, I., Vecchi, E. R., Favagrossa, M., Costanza, M., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01745-x · Cited by 18 · see citing works

A Single Dose of Pirfenidone Attenuates Neuronal Loss and Reduces Lipid Peroxidation after Kainic Acid-Induced Excitotoxicity in the Pubescent Rat Hippocampus

Castro-Torres, R. D., Chaparro-Huerta, V., Flores-Soto, M. E., Bañuelos‐Pineda, J., Camins, A., Orozco-Suárez, S. A., Armendáriz‐Borunda, J., & Beas‐Zárate, C. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-0121-6 · Cited by 17 · see citing works

NMDA glutamate receptors in Alzheimer's disease

Mishizen-Eberz, A. J., & Armstrong, D. M. (2001) · doi:10.17918/00009291

Differential expression of N‐methyl‐d‐aspartate receptor NR2 isoforms in Alzheimer's disease

Hynd, M., Scott, H., & Dodd, P. R. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02548.x · Cited by 118 · see citing works

N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease

Bi, H., & Sze, C. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00087-4 · Cited by 111 · see citing works

Expressions of NMDA receptor subunits NR2B and NR2A and their relationship with apoptosis in the hippocampus of Alzheimer′s disease-like rats

Zhao, W. (2011) · Journal of Shandong University

Selective loss of NMDA receptor NR1 subunit isoforms in Alzheimer's disease

Hynd, M., Scott, H., & Dodd, P. R. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2003.02330.x · Cited by 56 · see citing works