The DOI matches its Crossref record.
An algorithm accounting for plating efficiency in estimating spontaneous mutation rates
Abstract
An algorithm is described for calculating the probability distribution of the number of mutant colonies arising in a Luria-Delbrück fluctuation experiment subject to a plating efficiency of less than 100%. A table is constructed to facilitate the estimation of spontaneous mutation rates taking into account the plating efficiency.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Delayed phenotypic expression of a mutant phenotype has the biggest impact on the lower tail of mutant distribution [5,10,33], and this fact is reflected in the shapes of empirical CDFs in Figure 4.”
From Efficient, robust, and versatile fluctuation data analysis using MLE MUtation Rate calculator (mlemur) (2023) · cites this paper as [33]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 10
- Luria, 1943, Mutations of bacteria from virus sensitivity to virus resistance, Genetics, 28, 491, 10.1093/genetics/28.6.491 · DOI · Paper page
- Lea, 1949, The distribution of the numbers of mutants in bacterial populations, J. Genet., 49, 264, 10.1007/BF02986080 · DOI · Paper page
- Featherstone, 1987, Problems and pitfalls in assessing human T-lymphocyte mutant frequencies, Mutat. Res., 179, 215, 10.1016/0027-5107(87)90312-5 · DOI
- Kendal, 1988, Pitfalls and practice of Luria-Delbrück fluctuation analysis: a review, Cancer Res., 48, 1060
- Feller, 1968, Vol. 1, 264
- Knuth, 1981, Vol. 2, 25
- Press, 1986, 194
- Capizzi, 1973, A table for the estimation of the spontaneous mutation rate of cells in culture, Mutat. Res., 17, 147, 10.1016/0027-5107(73)90265-0 · DOI
- Armitage, 1952, The statistical theory of bacterial populations subject to mutation, J. R. statist. Soc., B14, 1, 10.1111/j.2517-6161.1952.tb00098.x · DOI · Paper page
- Li, 1987, Evaluation of methods for the estimation of mutation rates in cultured mammalian cell populations, Mutat. Res., 190, 281, 10.1016/0165-7992(87)90010-8 · DOI
Cited by
Sorted by citations
Łazowski, K. (2023) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2023.111816 · Cited by 9
Metadata
- Authors
- Jones, M. E.
- Affiliations
- Flinders University (AU)
- Corresponding author
- Jones, Michael E.
- ORCID
- Jones, Michael E.
- Venue
- Computers in Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 1993-11
- Volume
- 23
- Issue
- 6
- Pages
- 455-461
- ISSN
- 0010-4825 (ISSN-L)
- OpenAlex
- W2013963802
- Cited by
- 8
- References
- 0
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Computers in Biology and Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Physical Sciences › Mathematics › Statistics and Probability › Probability and Statistical Research
- Keywords
- plating efficiency, spontaneous mutation rate, probability distributions, mutation rate estimation, bacterial mutagenesis
- MeSH terms
- Algorithms, Cells, Cultured, Clone Cells, Models, Genetic, Mutation, Probability, Selection, Genetic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: An algorithm accounting for plating efficiency in estimating spontaneous mutation rates. https://app.cochat.ai/papers/10.1016/0010-4825(93)90093-g
- The paper
- Jones, M. E. (1993). An algorithm accounting for plating efficiency in estimating spontaneous mutation rates. Computers in Biology and Medicine. https://doi.org/10.1016/0010-4825(93)90093-g
