Ancylostoma caninum: Adult worm removal, corticosteroid treatment, and resumed development of arrested larvae in dogs
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In A. caninum infection, arrested somatic larvae continuously migrate to the small intestine where they develop to the adult stage, a phenomenon known as "larval leak".
“An interesting biological feature of A. caninum infection is the phenomenon known as “larval leak”, where arrested somatic larvae continuously migrate to the small intestine where they develop to the adult stage [9, 19].”
From Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat? (2019) · cites this paper as [19]
In older dogs, most A. caninum larvae penetrate peripheral somatic tissues such as muscle or gut wall, where they enter an arrested state and can survive for several years.
“rather than the lungs, most of the larvae penetrate peripheral organs (somatic tissues) such as muscle (M.D. Little, unpublished observations) or gut wall [18], where they enter into an arrested state and are capable of surviving for several years [19].”
From Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat? (2019) · cites this paper as [19]
Cites
Parasitology for veterinarians
Georgi, J. R. (1974) · Medical Entomology and Zoology · Cited by 340 · see citing works
Arrested Development of Nematodes and some Related Phenomena
Michel, J. F. (1974) · Advances in Parasitology/Advances in parasitology · doi:10.1016/s0065-308x(08)60390-5 · Cited by 198 · see citing works
Parasitology for Veterinarians
Armour, J. (1981) · Journal of Small Animal Practice · doi:10.1111/j.1748-5827.1981.tb01392.x · Cited by 64 · see citing works
The Role of Arrested Development in the Regulation of Nematode Populations
Schad, G. A. (1977) · Elsevier eBooks · doi:10.1016/b978-0-12-241750-4.50009-0 · Cited by 58 · see citing works
Self-citationStoye, M. (1973) · PubMed · Cited by 47 · see citing works
Stoye, M. (1973) · Zentralblatt für Veterinärmedizin Reihe B · doi:10.1111/j.1439-0450.1973.tb01098.x · Cited by 45 · see citing works
Kelly, J. D., & Dineen, J. K. (1973) · PubMed · Cited by 44 · see citing works
Necator americanus: Behaviour in hamsters
Sen, H. G. (1972) · Experimental Parasitology · doi:10.1016/0014-4894(72)90006-9 · Cited by 43 · see citing works
Ancylostoma duodenale: Maintenance through six generations in helminth-naive pups
Schad, G. A. (1979) · Experimental Parasitology · doi:10.1016/0014-4894(79)90077-8 · Cited by 39 · see citing works
Self-citationRegulation of Parasite Populations
(1977) · Elsevier eBooks · doi:10.1016/b978-0-12-241750-4.x5001-7 · Cited by 31 · see citing works
The Biology of Hookworms in Their Hosts
Scott, J. A. (1930) · The Quarterly Review of Biology · doi:10.1086/394353 · Cited by 7 · see citing works
Proceedings of the British Society for Parasitology
(1974) · Parasitology · doi:10.1017/s0031182000048101 · Cited by 1 · see citing works
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Sorted by citations
Barker, I. K., & Dreumel, A. A. V. (1985) · Elsevier eBooks · doi:10.1016/b978-0-12-391602-0.50007-4 · Cited by 309 · see citing works
Immune Responses in Hookworm Infections
Loukas, A. C., & Prociv, P. (2001) · Clinical Microbiology Reviews · doi:10.1128/cmr.14.4.689-703.2001 · Cited by 230 · see citing works
Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?
Jimenez Castro, P. D., Howell, S. B., Schaefer, J. J., Avramenko, R. W., Gilleard, J. S., & Kaplan, R. M. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3828-6 · Cited by 192 · see citing works
Prociv, P., & Croese, J. (1996) · Acta Tropica · doi:10.1016/s0001-706x(96)00016-2 · Cited by 156 · see citing works
Hypobiosis in Parasitic Nematodes—An Update
Gibbs, H. C. (1986) · Advances in Parasitology/Advances in parasitology · doi:10.1016/s0065-308x(08)60343-7 · Cited by 145 · see citing works
Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans daf-c paradigm
Hotez, P. J., Hawdon, J. M., & Schad, G. A. (1993) · Parasitology Today · doi:10.1016/0169-4758(93)90159-d · Cited by 135 · see citing works
Self-citationBarker, I. K., Dreumel, A. A. V., & PALMER, N. (1993) · Elsevier eBooks · doi:10.1016/b978-0-12-391606-8.50009-0 · Cited by 125 · see citing works
Kitchen, S., Ratnappan, R., Han, S., Leasure, C., Grill, E., Iqbal, Z., Granger, O., O'Halloran, D. M., & Hawdon, J. M. (2019) · International Journal for Parasitology · doi:10.1016/j.ijpara.2018.12.004 · Cited by 105 · see citing works
Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum.
Hotez, P. J., Trang, N. L., McKerrow, J. H., & Cerami, A. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39614-x · Cited by 102 · see citing works
Elsemore, D. A., Geng, J., Cote, J., Hanna, R., Lucio‐Forster, A., & Bowman, D. D. (2017) · Journal of Veterinary Diagnostic Investigation · doi:10.1177/1040638717706098 · Cited by 76 · see citing works
Kopp, S. R., Coleman, G. T., McCarthy, J. S., & Kotze, A. C. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2007.12.020 · Cited by 68 · see citing works
Diapause in parasitic nematodes: a review
Sommerville, R. I., & Davey, K. G. (2002) · Canadian Journal of Zoology · doi:10.1139/z02-163 · Cited by 62 · see citing works
Brand, A., & Hawdon, J. M. (2004) · International Journal for Parasitology · doi:10.1016/j.ijpara.2004.04.003 · Cited by 54 · see citing works
Traub, R. J., Pednekar, R. P., Cuttell, L., Porter, R. B., Rani, P. A. M. A., & Gatne, M. L. (2014) · Veterinary Parasitology · doi:10.1016/j.vetpar.2014.06.037 · Cited by 49 · see citing works
Shepherd, C., Wangchuk, P., & Loukas, A. C. (2018) · Parasites & Vectors · doi:10.1186/s13071-018-2621-2 · Cited by 41 · see citing works
Hawdon, J. M. (1996) · Journal of Parasitology · doi:10.2307/3283794 · Cited by 39 · see citing works
Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum
Brand, A., Varghese, G., Majewski, W., & Hawdon, J. M. (2005) · International Journal for Parasitology · doi:10.1016/j.ijpara.2005.07.004 · Cited by 38 · see citing works
Ancylostoma caninum and Other Canine Hookworms
Hawdon, J. M., & Wise, K. A. (2020) · Parasitology research monographs · doi:10.1007/978-3-030-53230-7_9 · Cited by 37 · see citing works
Coproantigen Detection Augments Diagnosis of Common Nematode Infections in Dogs
Little, S. E., Barrett, A. W., Beall, M. J., Bowman, D. D., Dangoudoubiyam, S., Elsemore, D. A., Liotta, J. L., Lucio‐Forster, A., McCrann, D. J., Snowden, K. F., et al. (2019) · Topics in companion animal medicine · doi:10.1053/j.tcam.2019.04.001 · Cited by 34 · see citing works
Combination Anthelmintic Treatment for Persistent Ancylostoma caninum Ova Shedding in Greyhounds
Hess, L. B., Millward, L. M., Rudinsky, A., Vincent, E., & Marsh, A. (2019) · Journal of the American Animal Hospital Association · doi:10.5326/jaaha-ms-6904 · Cited by 32 · see citing works
Marsh, A. E., & Lakritz, J. (2023) · International Journal for Parasitology Drugs and Drug Resistance · doi:10.1016/j.ijpddr.2023.04.003 · Cited by 29 · see citing works
Arasu, P. (2001) · Journal of Parasitology · doi:10.1645/0022-3395(2001)087[0733:ivroac]2.0.co;2 · Cited by 28 · see citing works
Pathogenesis of Human Hookworm Infection: Insights from a &Isquo;New� Zoonosis
Prociv, P. (1997) · KARGER eBooks · doi:10.1159/000058666 · Cited by 26 · see citing works
Ancylostoma caninum: Reduced glutathione stimulates feeding by third-stage infective larvae
Hawdon, J. M., & Schad, G. A. (1992) · Experimental Parasitology · doi:10.1016/0014-4894(92)90120-y · Cited by 25 · see citing works
Self-citationArasu, P., & Kwak, D. (1999) · Journal of Parasitology · doi:10.2307/3285811 · Cited by 25 · see citing works
Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms
Gao, X., Frank, D. N., & Hawdon, J. M. (2008) · International Journal for Parasitology · doi:10.1016/j.ijpara.2008.09.005 · Cited by 24 · see citing works
Beknazarova, M., Whiley, H., Traub, R. J., & Ross, K. (2020) · Pathogens · doi:10.3390/pathogens9050398 · Cited by 21 · see citing works
Schroeder, N. E., & MacGuidwin, A. E. (2010) · Nematology · doi:10.1163/138855409x12506855979712 · Cited by 21 · see citing works
Vicente, J., Palomares, F., de Ibañez, A. R., & Ortíz, J. M. (2004) · Journal of Helminthology · doi:10.1079/joh2003216 · Cited by 19 · see citing works
Gillespie, S. H. (2004) · Current Infectious Disease Reports · doi:10.1007/s11908-004-0024-3 · Cited by 17 · see citing works
Becskei, C., Thys, M., Kryda, K., Meyer, L. N., Martorell, S., Geurden, T., Dreesen, L., Fernandes, T., & Mahabir, S. P. (2020) · Parasites & Vectors · doi:10.1186/s13071-020-3951-4 · Cited by 15 · see citing works
Krepp, J. M., Gelmedin, V., & Hawdon, J. M. (2010) · International Journal for Parasitology · doi:10.1016/j.ijpara.2010.12.001 · Cited by 13 · see citing works
Niamatali, S., Bhopale, V. M., & Schad, G. A. (1992) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1992.201.09.1385 · Cited by 13 · see citing works
Self-citationDevelopmental arrest of Haemonchus contortus in sheep treated with a corticosteroid
Adams, D. (1986) · International Journal for Parasitology · doi:10.1016/0020-7519(86)90036-6 · Cited by 13 · see citing works
Nielsen, M. K., Kaplan, R. M., Abbas, G., & Jabbar, A. (2023) · Trends in Parasitology · doi:10.1016/j.pt.2023.08.002 · Cited by 12 · see citing works
Bowman, D. D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-54396-5.00013-1 · Cited by 13 · see citing works
Chitwood, D. J. (1992) · AOCS Publishing eBooks · doi:10.1201/9781439821831.ch9 · Cited by 10 · see citing works
Geary, T. G., Drake, J., Gilleard, J. S., Chelladurai, J. R. J. J., Castro, P. D. J., Kaplan, R. M., Marsh, A. E., Reinemeyer, C. R., & Verocai, G. G. (2025) · Veterinary Parasitology · doi:10.1016/j.vetpar.2025.110536 · Cited by 9 · see citing works
dos Santos, B., da Silva, A. N. F., Mora, S. E. V., Neto, V. A. K., Justo, A. A., Pantoja, J. C. F., Schmidt, E. M. D. S., & Takahira, R. K. (2020) · Veterinary Parasitology Regional Studies and Reports · doi:10.1016/j.vprsr.2020.100452 · Cited by 9 · see citing works
Hookworm infection: molecular mechanisms of disease and targets for control
Jones, B. F., & Cappello, M. (2004) · Drug Discovery Today Disease Mechanisms · doi:10.1016/j.ddmec.2004.10.004 · Cited by 8 · see citing works
Bowman, D. D., Lucio‐Forster, A., & Lee, A. C. Y. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-50934-3.00113-0 · Cited by 7 · see citing works
Arasu, P., & Heller, A. (1999) · Veterinary Immunology and Immunopathology · doi:10.1016/s0165-2427(99)00081-1 · Cited by 7 · see citing works
Immunity mediates host specificity in the human hookworm Ancylostoma ceylanicum
Langeland, A., McKean, E. L., O’Halloran, D. M., & Hawdon, J. M. (2023) · Parasitology · doi:10.1017/s0031182023001208 · Cited by 6 · see citing works
Watkins, A. R. J., & Fernando, M. A. (1986) · International Journal for Parasitology · doi:10.1016/0020-7519(86)90064-0 · Cited by 6 · see citing works
Evason, M. D., DeBess, E. E., Culwell, N., Ogeer, J., & Leutenegger, C. M. (2024) · Journal of the American Animal Hospital Association · doi:10.5326/jaaha-ms-7366 · Cited by 5 · see citing works
Charles, S. D., Wiseman, S., Savadelis, M. D., Nichols, E. C., & Young, L. (2025) · Parasites & Vectors · doi:10.1186/s13071-025-06932-7 · Cited by 3 · see citing works
Nezami, R., Otis, C., Boyer, A., Blanchard, J., Moreau, M., Pelletier, J., Martel‐Pelletier, J., Godoy, P., & Troncy, É. (2024) · Veterinary Parasitology Regional Studies and Reports · doi:10.1016/j.vprsr.2024.101036 · Cited by 3 · see citing works
Epidemiology and molecular characterization of human and canine hookworm
Mudenda, N. B. (2013) · doi:10.31390/gradschool_dissertations.1209 · Cited by 2 · see citing works
Jackson, C. A., McKean, E. L., & Hawdon, J. M. (2024) · PubMed Central · doi:10.17912/micropub.biology.001360 · Cited by 1 · see citing works
Drug repurposing to combat multidrug-resistant hookworm
McKean, E. L., Jackson, C. A., Dowd, A. L., Hawdon, J. M., & O’Halloran, D. M. (2026) · Biology Open · doi:10.1242/bio.062380 · Cited by 1 · see citing works
Jackson, C. A., McKean, E. L., & Hawdon, J. M. (2025) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed10070181
McKean, E. L., Jackson, C. A., O’Halloran, D. M., & Hawdon, J. M. (2026) · Journal of Parasitology · doi:10.1645/25-80
- Authors
- Schad, G. A., & Page, M. R.
- Affiliations
- University of Pennsylvania (US)
- Venue
- Experimental Parasitology
- Publisher
- Elsevier BV
- Published
- 1982-12
- Volume
- 54
- Issue
- 3
- Pages
- 303-309
- ISSN
- 0014-4894 (ISSN-L)
- OpenAlex
- W2034920704
- Cited by
- 52
- References
- 12
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 3 · 2023: 3 · 2021: 2 · 2020: 4 · 2019: 4 · 2018: 1 · 2017: 1 · 2014: 1 · 2013: 1
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental Parasitology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Keywords
- Ancylostoma caninum, hookworm, hypobiosis, larval dormancy, dichlorvos, prednisolone, lymphocyte transformation, beagle dogs, canine hookworm infection
- MeSH terms
- Ancylostoma, Ancylostomiasis, Animals, Anthelmintics, Dichlorvos, Dog Diseases, Dogs, Feces, Larva, Nitrophenols, Prednisolone
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