The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts
Open accessAbstract
Fibronectin (FN) polymorphism is caused by alternative splicing patterns in at least three regions of the primary transcript of a single gene. Using a monoclonal antibody (Mab) specific for an FN segment (ED‐A), that can be included or omitted from the molecule depending on the pattern of splicing, we have examined whether transforming growth factor β (TGF‐β) and dexamethasone, which are both known to increase the level of total FN, regulate the levels of different FN isoforms. We found that, while dexamethasone does not significantly change the ratio between the total FN and the ED‐A containing FN, TGF‐β preferentially increases the expression of the FN isoform containing the ED‐A sequence.
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Cites
Ignotz, R. A., & Massagué, J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35666-1 · Cited by 2,492
Cited by
Serini, G., Bochaton-Piallat, M.-L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L., & Gabbiani, G. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.3.873 · Cited by 847
Self-citationDedifferentiation and Proliferation of Surviving Epithelial Cells in Acute Renal Failure
Bonventre, J. V. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000067652.51441.21 · Cited by 593
Lampi, M. C., & Reinhart-King, C. A. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aao0475 · Cited by 551
New insights into form and function of fibronectin splice variants
White, E., Baralle, F., & Muro, A. (2008) · The Journal of Pathology · doi:10.1002/path.2388 · Cited by 323
Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model.
Wolf, Y. G., Rasmussen, L. M., & Ruoslahti, E. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117070 · Cited by 304
Metadata
- Authors
- Balza, E., Borsi, L., Allemanni, G., & Zardi, L.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1988-02-08
- Volume
- 228
- Issue
- 1
- Pages
- 42-44
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2048055673
- Cited by
- 182
- References
- 1
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Balza, E., Borsi, L., Allemanni, G., & Zardi, L. (1988). Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts. FEBS Letters. https://doi.org/10.1016/0014-5793(88)80580-5
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
