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Cited by 180

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes

Open access
Goris, Jozef, Hermann, Jacques, Hendrix, Peter, Ozon, René, Merlevede, Wilfried·1989·FEBS Letters

Abstract

Micro‐injection of, or incubation with okadaic acid (OA), a specific phosphatase inhibitor, can induce formation of maturation‐promoting factor (MPF) and germinal vesicle breakdown (GVBD) in Xenopus laevis oocytes. Comparison of the dose‐response curves of OA on maturation, isolated enzymes and phosphatase activities in crude oocyte preparations suggests that inhibition of both polycation‐stimulated (PCS) and ATP,Mg‐dependent (AMD) phosphatases is sufficient but requires that a critical phosphorylation level is attained of one or several of their substrates, resulting in the formation of active MPF and meiotic maturation.

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Metadata

Authors
Goris, J., Hermann, J., Hendrix, P., Ozon, R., & Merlevede, W.
Venue
FEBS Letters
Publisher
Wiley
Published
1989-03-13
Volume
245
Issue
1-2
Pages
91-94
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W1992529920
Cited by
180
References
1
FWCI
30.29
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes. https://app.cochat.ai/papers/10.1016/0014-5793(89)80198-x
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Goris, J., Hermann, J., Hendrix, P., Ozon, R., & Merlevede, W. (1989). Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes. FEBS Letters. https://doi.org/10.1016/0014-5793(89)80198-x

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