The DOI matches its Crossref record.
The human 32‐kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase
Abstract
Exposure of HeLa and HL60 cells to sodium arsenite or cadmium chloride led to marked increases in cellular heme oxygenase activity. SDS‐polyacrylamide gel clectrophoresis of [35S]methionine‐labeled cellular proteins indicated that these treatments also resulted in the induction of a 32‐kDa protein. Immunoblot analysis further showed that the 32‐kDa protein reacted with anti‐bovine heme oxygenase antibodies. Treatment of the cells with cobaltic chloride or heat induced neither the 32‐kDa protein nor heme oxygenase activity. It is concluded that the 32‐kDa stress protein induced by arsenite and cadmium ions in these human cells is heme oxygenase.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Oxidative mechanisms in the toxicity of metal ions
Stohs, S. J., & Bagchi, D. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00159-h · Cited by 4,219
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
Ryter, S. W., Alam, J., & Choi, A. M. K. (2006) · Physiological Reviews · doi:10.1152/physrev.00011.2005 · Cited by 2,307
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
Yachie, A., Niida, Y., Wada, T., Igarashi, N., Kaneda, H., Toma, T., Ohta, K., Kasahara, Y., & Koizumi, S. (1999) · Journal of Clinical Investigation · doi:10.1172/jci4165 · Cited by 1,255
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene
Sun, J., Hoshino, H., Takaku, K., Nakajima, O., Muto, A., Suzuki, H., Tashiro, S., Takahashi, S., Shibahara, S., Alam, J., et al. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf516 · Cited by 637
Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts.
Vile, G. F., Basu-Modak, S., Waltner, C., & Tyrrell, R. M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.7.2607 · Cited by 517
Metadata
- Authors
- Taketani, S., Kohno, H., Yoshinaga, T., & Tokunaga, R.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1989-03-13
- Volume
- 245
- Issue
- 1-2
- Pages
- 173-176
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2078349020
- Cited by
- 164
- References
- 0
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The human 32‐kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase. https://app.cochat.ai/papers/10.1016/0014-5793(89)80215-7
- The paper
- Taketani, S., Kohno, H., Yoshinaga, T., & Tokunaga, R. (1989). The human 32‐kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase. FEBS Letters. https://doi.org/10.1016/0014-5793(89)80215-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
