The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Potent selective inhibitors of protein kinase C
Open accessAbstract
A series of potent, selective inhibitors of protein kinase C has been derived from the structural lead provided by the microbial broth products, staurosporine and K252a. Our inhibitors block PCK in intact cells (platelets and T cells), and prevent the proliferation of mononuclear cells in response to interleukin 2 (IL2).
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Citations
Cites
1 retracted
Meyer, T., Regenass, U., Fabbro, D., Alteri, E., Röusel, J., Möller, M., Caravatti, G., & Matter, A. (1989) · International Journal of Cancer · doi:10.1002/ijc.2910430519 · Cited by 407
RetractedThe role of protein kinase C in cell surface signal transduction and tumour promotion
Nishizuka, Y. (1984) · Nature · doi:10.1038/308693a0 · Cited by 7,454
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
Nishizuka, Y. (1988) · Nature · doi:10.1038/334661a0 · Cited by 4,171
Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase
Tamaoki, T., Nomoto, H., Takahashi, I., Kato, Y., Morimoto, M., & Tomita, F. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(86)90008-2 · Cited by 2,452
Kikkawa, U., Takai, Y., Minakuchi, R., Inohara, S., & Nishizuka, Y. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33453-7 · Cited by 1,003
Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A., & Kaneko, M. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)90293-2 · Cited by 938
Takai, Y., Kishimoto, A., Kikkawa, U., Mori, T., & Nishizuka, Y. (1979) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(79)91197-5 · Cited by 731
Burt, C. T., Glonek, T., & Bárány, M. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33527-5 · Cited by 339
Goldenring, J. R., Gonzalez, B., McGuire, J. S., & DeLorenzo, R. J. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44223-2 · Cited by 338
Molecular cloning and expression of the major protein kinase C substrate of platelets
Tyers, M., Rachubinski, R. A., Stewart, M. I., Varrichio, A. M., Shorr, R. G. L., Haslam, R. J., & Harley, C. B. (1988) · Nature · doi:10.1038/333470a0 · Cited by 255
Cited by
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
Wilkinson, S. E., Parker, P. J., & Nixon, J. S. (1993) · Biochemical Journal · doi:10.1042/bj2940335 · Cited by 522
Self-citationWeinstein, S. L., Sanghera, J. S., Lemke, K., DeFranco, A. L., & Pelech, S. L. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42133-3 · Cited by 396
Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages.
Weinstein, S. L., Gold, M. R., & DeFranco, A. L. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.10.4148 · Cited by 311
Enzastaurin: A lesson in drug development
Bourhill, T., Narendran, A., & Johnston, R. N. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.02.003 · Cited by 55
Metadata
- Authors
- Davis, P. D., Hill, C. H., Keech, E., Lawton, G., Nixon, J. S., Sedgwick, A. D., Wadsworth, J., Westmacott, D., & Wilkinson, S. E.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1989-12-18
- Volume
- 259
- Issue
- 1
- Pages
- 61-63
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2015648136
- Cited by
- 477
- References
- 14
- FWCI
- 9.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Potent selective inhibitors of protein kinase C. https://app.cochat.ai/papers/10.1016/0014-5793(89)81494-2
- The paper
- Davis, P. D., Hill, C. H., Keech, E., Lawton, G., Nixon, J. S., Sedgwick, A. D., Wadsworth, J., Westmacott, D., & Wilkinson, S. E. (1989). Potent selective inhibitors of protein kinase C. FEBS Letters. https://doi.org/10.1016/0014-5793(89)81494-2
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
