The DOI matches its Crossref record.
Direct activation of GTP‐binding regulatory proteins (G‐proteins) by substance P and compound 48/80
Abstract
The neuropeptide substance P and the polyamine compound , both known to activate mast cell secretory processes, increased the rate of GTP γ S binding to G‐proteins purified from calf brain (G o/G i mixture). The GTPase activity of G‐proteins was also increased by substance P and compound in a dose‐dependent and Mg 2+‐dependent way. These effects were similar to those of the wasp venom peptide rnastoparan, another histamine releaser of rat peritoneal and human skin mast cells. This suggests that the secretory property of compound and substance P is not due to a receptor‐mediated process but, like mastoparan, results from a direct activation of G‐proteins.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
G Protein-Coupled Receptor Allosterism and Complexing
Christopoulos, A., & Kenakin, T. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.2.323 · Cited by 931
Neuronal Control of Skin Function: The Skin as a Neuroimmunoendocrine Organ
Roosterman, D., Goerge, T., Schneider, S. W., Bunnett, N. W., & Steinhoff, M. (2006) · Physiological Reviews · doi:10.1152/physrev.00026.2005 · Cited by 665
Mast cells differentially express and release active high molecular weight neurotrophins
Skaper, S. D., Pollock, M., & Facci, L. (2001) · Molecular Brain Research · doi:10.1016/s0169-328x(01)00314-x · Cited by 99
Bradesi, S., Eutamene, H., Fioramonti, J., & Bueno, L. (2002) · Gut · doi:10.1136/gut.50.3.349 · Cited by 34
Metadata
- Authors
- Mousli, M., Bronner, C., Landry, Y., Bockaert, J., & Rouot, B.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1990-01
- Volume
- 259
- Issue
- 2
- Pages
- 260-262
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2045917231
- Cited by
- 299
- References
- 0
- FWCI
- 9.48
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Direct activation of GTP‐binding regulatory proteins (G‐proteins) by substance P and compound 48/80. https://app.cochat.ai/papers/10.1016/0014-5793(90)80023-c
- The paper
- Mousli, M., Bronner, C., Landry, Y., Bockaert, J., & Rouot, B. (1990). Direct activation of GTP‐binding regulatory proteins (G‐proteins) by substance P and compound 48/80. FEBS Letters. https://doi.org/10.1016/0014-5793(90)80023-c
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
