The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Antioxidant system in rat testicular cells
Abstract
The activity of the enzymes involved in the antioxidant defence — superoxide dismutase (SOD), glutathione peroxidase (GPx), reductase (GR) S‐transferase (GST) — as well as the glutathione (GSH) levels were measured in different rat testicular cell populations. A differential distribution of these components among testicular cell types was clearly observed. Sertoli and peritubular cells had elevated SOD and GSH‐dependent enzyme activities associated with a high GSH content. Compared with the somatic cells, pachytene spermatocytes (PS) round spermatids (RS) presented a different antioxidant system characterized by higher SOD activity and GSH content associated with very low GSH‐dependent enzyme activity. Spermatozoa exhibited the same enzymatic system as PS and RS but were devoid of GSH. Interstitial tissue displayed high GSH content, moderate SOD and GSH‐related enzyme activity except for GPx which was very elevated. It is concluded that the different categories of testicular cells probably display a highly variable susceptibility to oxidative stress.
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Cites
Modification of DNA bases in mammalian chromatin by radiation-generated free radicals
Gajewski, E., Rao, G., Nackerdien, Z., & Dizdaroglu, M. (1990) · Biochemistry · doi:10.1021/bi00486a014 · Cited by 258
Cited by
Role of oxidative stress in germ cell apoptosis induced by di(2-ethylhexyl)phthalate
KASAHARA, E., SATO, E. F., MIYOSHI, M., KONAKA, R., HIRAMOTO, K., SASAKI, J., TOKUDA, M., NAKANO, Y., & INOUE, M. (2002) · Biochemical Journal · doi:10.1042/bj20020254 · Cited by 313
Paul, C., & Robaire, B. (2013) · Nature Reviews Urology · doi:10.1038/nrurol.2013.18 · Cited by 109
Metadata
- Authors
- Bauché, F., Fouchard, M.-H., & Jégou, B.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1994-08-08
- Volume
- 349
- Issue
- 3
- Pages
- 392-396
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1970384337
- Cited by
- 297
- References
- 1
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bauché, F., Fouchard, M.-H., & Jégou, B. (1994). Antioxidant system in rat testicular cells. FEBS Letters. https://doi.org/10.1016/0014-5793(94)00709-8
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
