The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Mitochondrial respiratory chain inhibitors induce apoptosis
Open accessAbstract
In this paper the specific mitochondrial respiratory chain inhibitors rotenone and antimycin A and the highly specific mitochondrial ATP‐synthase inhibitor oligomycin are shown to induce an apoptotic suicide response in cultured human lymphoblastoid and other mammalian cells within 12–18 h. The mitochondrial inhibitors do not induce apoptosis in cells depleted of mitochondrial DNA and thus lacking an intact mitochondrial respiratory chain. Apoptosis induced by respiratory chain inhibitors is not inhibited by the presence of Bcl‐2. We discuss the possible role of mitochondrial induced apoptosis in the ageing process and age‐associated diseases.
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“, rotenone) (Wolvetang et al., 1994) or by disruption of iron-sulfur clusters in the mitochondrial complexes themselves (Napoli et al.”
Metadata
- Authors
- Wolvetang, E. J., Johnson, K. L., Krauer, K., Ralph, S. J., & Linnane, A. W.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1994-02-14
- Volume
- 339
- Issue
- 1-2
- Pages
- 40-44
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2050365720
- Cited by
- 398
- References
- 20
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Mitochondrial respiratory chain inhibitors induce apoptosis. https://app.cochat.ai/papers/10.1016/0014-5793(94)80380-3
- The paper
- Wolvetang, E. J., Johnson, K. L., Krauer, K., Ralph, S. J., & Linnane, A. W. (1994). Mitochondrial respiratory chain inhibitors induce apoptosis. FEBS Letters. https://doi.org/10.1016/0014-5793(94)80380-3
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
