Cerebellar lamellar bodies in two strains of murine scrapie
Abstract
Lamellar inclusion bodies have been described by other authors in the granular layer of the cerebellum of people suffering from the unconventional slow-virus disease of kuru and were thought to be associated with the disease. In this study, these bodies were also found in mice infected with scrapie, which belongs to the same group of diseases, as well as their age-matched controls.
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Peat and Field reported cytoplasmic lamellar bodies, which were subsequently shown to be normal cell constituents.
“Peat and Field (82) reported on “cytoplasmic lamellar bodies,” which subsequently were shown to be perfectly normal cell constituents (83).”
From Kuru (2012) · cites this paper as [83]
Cites
An unusual structure in Kuru brain
Peat, A., & Field, E. J. (1970) · Acta Neuropathologica · doi:10.1007/bf00686775 · Cited by 13 · see citing works
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Liberski, P. P., Sikorska, B., Lindenbaum, S., Goldfarb, L. G., McLean, C., Hainfellner, J. A., & Brown, P. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3182444efd · Cited by 50 · see citing works
“Peat and Field (82) reported on ‘‘cytoplasmic lamellar bodies,’’ which subsequently were shown to be perfectly normal cell constituents (83).”
BackgroundSelf-citation
- Authors
- Liberski, P. P., & Gibson, P. H.
- Affiliations
- Medical University of Lodz (PL)
- ORCID
- Liberski, P.P.
- Venue
- Journal of Comparative Pathology
- Publisher
- Elsevier BV
- Published
- 1987-07
- Volume
- 97
- Issue
- 4
- Pages
- 491-493
- ISSN
- 0021-9975 (ISSN-L)
- OpenAlex
- W1973111135
- Cited by
- 5
- References
- 1
- Citations by year
- 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Comparative Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Prion Diseases and Protein Misfolding
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Amyloidosis: Diagnosis, Treatment, Outcomes
- Keywords
- scrapie, cerebellum, lamellar bodies, granular layer, kuru, slow viruses, prion disease
- MeSH terms
- Animals, Cerebellum, Inclusion Bodies, Viral, Mice, Inbred C3H, Microscopy, Electron, Scrapie, Mice
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