The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
A general method applicable to the search for similarities in the amino acid sequence of two proteins
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Citations
Cites
Bryson, V., & Vogel, H. J. (1965) · Science · doi:10.1126/science.147.3653.68 · Cited by 1,343
The Amino Acid Sequence of Egg White Lysozyme
Canfield, R. E. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67888-3 · Cited by 739
The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations
Smyth, D. G., Stein, W. H., & Moore, S. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83984-4 · Cited by 567
Amino-Acid Sequence of Sperm Whale Myoglobin
Edmundson, A. B. (1965) · Nature · doi:10.1038/205883a0 · Cited by 396
Meisel, P. (1971) · Food / Nahrung · doi:10.1002/food.19710150234 · Cited by 346
An improved method of testing for evolutionary homology
Fitch, W. M. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80258-9 · Cited by 313
Fine Structure of RNA Codewords Recognized by Bacterial, Amphibian, and Mammalian Transfer RNA
Marshall, R. E., Caskey, C. T., & Nirenberg, M. W. (1967) · Science · doi:10.1126/science.155.3764.820 · Cited by 147
The Structure of Human Hemoglobin
Konigsberg, W. H., & Hill, R. (1962) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50137-x · Cited by 115
The Structure of Human Hemoglobin
Konigsberg, W. H., Goldstein, J., & Hill, R. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67936-0 · Cited by 76
A Comparison of the Amino Acid Sequences of the Cytochrome c of Several Vertebrates.
Margoliash, E., Needleman, S. B., Stewart, J. W., & Takahashi, M. T. (1963) · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · doi:10.3891/acta.chem.scand.17s-0250 · Cited by 25
Self-citation
Research works printed but not linked: 1
- Needleman, 1969, 63, 1127
Cited by
Sorted by citations
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Altschul, S. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.17.3389 · Cited by 73,302
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617
MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform
Katoh, K. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf436 · Cited by 17,027
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
Brooks, B., Bruccoleri, R., Olafson, B. D., States, D., Swaminathan, S., & Karplus, M. (1983) · Journal of Computational Chemistry · doi:10.1002/jcc.540040211 · Cited by 13,736
Metadata
- Authors
- Needleman, S. B., & Wunsch, C. D.
- Affiliations
- Northwestern University (US)
- Venue
- Journal of Molecular Biology
- Publisher
- Elsevier BV
- Published
- 1970-03
- Volume
- 48
- Issue
- 3
- Pages
- 443-453
- ISSN
- 0022-2836 (ISSN-L)
- OpenAlex
- W2074231493
- Cited by
- 11,288
- References
- 11
- Citations by year
- 2026: 212 · 2025: 270 · 2024: 379 · 2023: 369 · 2022: 358 · 2021: 420 · 2020: 415 · 2019: 356 · 2018: 403 · 2017: 359 · 2016: 380 · 2015: 383 · 2014: 436 · 2013: 441 · 2012: 423
- FWCI
- 4.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fractal and DNA sequence analysis
- Physical Sciences › Mathematics › Theoretical Computer Science › Algorithms and Data Compression
- Keywords
- protein sequence comparison, amino acid sequence similarity, protein homology, protein evolution, dynamic programming, two-dimensional arrays, computational algorithms
- MeSH terms
- Amino Acid Sequence, Computers, Hemoglobins, Methods, Muramidase, Myoglobin, Probability, Ribonucleases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
