Interpretation of the meridional X-ray diffraction pattern from collagen fibrils in corneal stroma
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There are about 70 microfibrils within each corneal collagen fibril, tilted by about 15° to the fibril long axis, and this reduces the usual 67 nm axial periodicity seen in tendon and sclera to closer to 65 nm.
“There are about 70 microfibrils within each fibril (Holmes and Kadler, 2005) which are tilted by about 15° to the fibril long axis (Holmes et al., 2001) and this reduces the usual 67 nm axial periodicity seen in tendon and sclera, to closer to 65 nm (Meek et al., 1981, Marchini et al., 1986, Yamamoto et al., 2000).”
From Corneal structure and transparency (2015) · cites this paper as Meek et al., 1981
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Corneal structure and transparency
Meek, K. M., & Knupp, C. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.07.001 · Cited by 853 · see citing works
Self-citation
- Authors
- Meek, K. M., Elliott, G. F., Sayers, Z., Whitburn, S. B., & Koch, M. H. J.
- Affiliations
- The Open University (GB)
- European Molecular Biology Laboratory (DE)
- Venue
- Journal of Molecular Biology
- Publisher
- Elsevier BV
- Published
- 1981-07
- Volume
- 149
- Issue
- 3
- Pages
- 477-488
- ISSN
- 0022-2836 (ISSN-L)
- OpenAlex
- W1991024256
- Cited by
- 48
- References
- 0
- Citations by year
- 2023: 1 · 2020: 1 · 2019: 1 · 2016: 1 · 2015: 3 · 2014: 1
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Desy publication database (The Deutsches Elektronen-Synchrotron) (submittedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Corneal surgery and disorders
- Physical Sciences › Materials Science › Materials Chemistry › Enzyme Structure and Function
- Keywords
- corneal stroma, collagen fibrils, low-angle X-ray diffraction, meridional reflections, electron density profile, corneal lamellae, tendon collagen, hydroxylysine, sugar-binding site, cornea
- MeSH terms
- Animals, Cattle, Collagen, Cornea, Microscopy, Electron, X-Ray Diffraction, Rats
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